Investigadores
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Investigadores
Fundación de Investigación Oftalmológica de Asturias (CCST). Oviedo.
Terapia Génica
Terapia de células somáticas y medicina regenerativa
Alvaro Meana Infiesta
Investigador principal
Grupo de Investigación: Fundación de Investigación Oftalmológica de Asturias (CCST). Oviedo.
Angeles Mencia Rodriguez
Investigador colaborador
Grupo de Investigación: Fundación de Investigación Oftalmológica de Asturias (CCST). Oviedo.
Carlos Leon Canseco
Investigador colaborador
Grupo de Investigación: Fundación de Investigación Oftalmológica de Asturias (CCST). Oviedo.
FERNANDO LARCHER LAGUZZI
Investigador colaborador
Grupo de Investigación: Fundación de Investigación Oftalmológica de Asturias (CCST). Oviedo.
Lucía Martínez Santamaría
Investigador colaborador
Grupo de Investigación: Fundación de Investigación Oftalmológica de Asturias (CCST). Oviedo.
Manuel Chacón Rodríguez
Investigador colaborador
Grupo de Investigación: Fundación de Investigación Oftalmológica de Asturias (CCST). Oviedo.
Marcela del Río Nechaevsky
Investigador colaborador
Grupo de Investigación: Fundación de Investigación Oftalmológica de Asturias (CCST). Oviedo.
María José Escámez Toledano
Investigador colaborador
Grupo de Investigación: Fundación de Investigación Oftalmológica de Asturias (CCST). Oviedo.
Marta Carretero Trillo
Investigador colaborador
Grupo de Investigación: Fundación de Investigación Oftalmológica de Asturias (CCST). Oviedo.
MARTA GARCIA DIEZ
Investigador colaborador
Grupo de Investigación: Fundación de Investigación Oftalmológica de Asturias (CCST). Oviedo.
MARTA PEVIDA LÓPEZ
Investigador colaborador
Grupo de Investigación: Fundación de Investigación Oftalmológica de Asturias (CCST). Oviedo.
RODOLFO MURILLAS ANGOITI
Investigador colaborador
Grupo de Investigación: Fundación de Investigación Oftalmológica de Asturias (CCST). Oviedo.
Sara Gómez Llames
Investigador colaborador
Grupo de Investigación: Fundación de Investigación Oftalmológica de Asturias (CCST). Oviedo.
Sara Guerrero Aspizua
Investigador colaborador
Grupo de Investigación: Fundación de Investigación Oftalmológica de Asturias (CCST). Oviedo.
Alcalde I., Sánchez-Fernández C., Azpeitia Á., Vázquez N., Chacón M., Martín C., Merayo-Lloves J.. In vitro model of reconstructed human corneal epithelium for the evaluation of ocular surface desiccation and protection with vitamin A enriched ophthalmic ointment. Journal of Pharmaceutical Sciences. February 2025. DOI: 10.1016/j.xphs.2024.11.022.
Impacto: 3.7. Cuartil: Q2
Gallego L., Harvey K., Pevida M., García-Consuegra L., García-Suárez O., Meana Á., Alvarez-Viejo M., Junquera L.. From Waste to Innovation: A Circular Economy Approach for Tissue Engineering by Transforming Human Bone Waste into Novel Collagen Membranes. Biomolecules. January 2025. DOI: 10.3390/biom15010132.
Impacto: 4.8. Cuartil: Q1
Jover I., Ramos M.C., Escámez M.J., Lozoya E., Tormo J.R., de Prado-Verdún D., Mencía Á., Pont M., Puig C., Larraufie M.H., Gutiérrez-Caballero C., Reyes F., Trincado J.L., García-González V., Cerrato R., Andrés M., Crespo M., Vicente F., Godessart N., Genilloud O., Larcher F., Nueda A.. Identification of novel small molecule-based strategies of COL7A1 upregulation and readthrough activity for the treatment of recessive dystrophic epidermolysis bullosa. Scientific Reports. December 2024. DOI: 10.1038/s41598-024-67398-8.
Impacto: 3.8. Cuartil: Q1
Pleguezuelos-Beltrán P., Herráiz-Gil S., Martínez-Moreno D., Medraño-Fernandez I., León C., Guerrero-Aspizua S.. Regenerative Cosmetics: Skin Tissue Engineering for Anti-Aging, Repair, and Hair Restoration. Cosmetics. August 2024. DOI: 10.3390/cosmetics11040121.
Quintana-Castanedo L., Sánchez-Ramón S., Maseda R., Illera N., Pérez-Conde I., Molero-Luis M., Butta N., Arias-Salgado E.G., Monzón-Manzano E., Zuluaga P., Martínez-Santamaría L., Fernández-Arquero M., Llames S.G., Meana Á., de Lucas R., del Río M., Vicente Á., Escámez M.J., Sacedón R.. Unveiling the value of C-reactive protein as a severity biomarker and the IL4/IL13 pathway as a therapeutic target in recessive dystrophic epidermolysis bullosa: A multiparametric cross-sectional study. Experimental Dermatology. August 2024. DOI: 10.1111/exd.15146.
Impacto: 3.5. Cuartil: Q1
Lara-Sáez I., Mencía Á., Recuero E., Li Y., García M., Oteo M., Gallego M.I., Enguita A.B., de Prado-Verdún D., Sigen A., Wang W., García-Escudero R., Murillas R., Santos M.. Nonviral CRISPR/Cas9 mutagenesis for streamlined generation of mouse lung cancer models. Proceedings of the National Academy of Sciences of the United States of America. 9 July 2024. DOI: 10.1073/pnas.2322917121.
Impacto: 9.4. Cuartil: Q1
Chacón M., Vázquez N., Alonso-Alonso S., Llames S., Pevida M., Alcalde I., Merayo-Lloves J., Meana . Evaluating the QileX-RhE skin corrosion test for chemical subcategorization in accordance with OECD TG 431. Toxicology in Vitro. June 2024. DOI: 10.1016/j.tiv.2024.105816.
Impacto: 2.6. Cuartil: Q3
Alonso-Alonso S., Vázquez N., Chacón M., Caballero-Sánchez N., Del Olmo-Aguado S., Suárez C., Alfonso-Bartolozzi B., Fernández-Vega-Cueto L., Nagy L., Merayo-Lloves J., Meana A.. An effective method for culturing functional human corneal endothelial cells using a xenogeneic free culture medium. Scientific Reports. December 2023. DOI: 10.1038/s41598-023-46590-2.
Impacto: 3.8. Cuartil: Q1
Sacedón R., de Arriba M.C., Martínez-Santamaría L., Maseda R., Herráiz-Gil S., Jiménez E., Rosales I., Quintana L., Illera N., García M., Butta N., Fernández-Bello I., Lwin S.M., Fernández-Arquero M., León C., McGrath J.A., Vicente M.Á., del Río M., de Lucas R., Sánchez-Ramón S., Escámez M.J.. Gluten-sensitive enteropathy in recessive dystrophic epidermolysis bullosa. British Journal of Dermatology. December 2023. DOI: 10.1093/bjd/ljad313.
Impacto: 11.0. Cuartil: Q1
(1er decil)
Reyes M.A.C., Cabrera H.S., Canseco C.L.. MicroRNA Expression Profiling of Pancreatic Cancer Histological Subtypes in the Identification of Potential Biomarkers for Diagnosis and Tumor Prognosis. ACM International Conference Proceeding Series. 22 September 2023. DOI: 10.1145/3632047.3632057.
Herráiz-Gil S., del Carmen de Arriba M., Escámez M.J., León C.. Multi-omic data integration in food science and analysis. Current Opinion in Food Science. August 2023. DOI: 10.1016/j.cofs.2023.101049.
Impacto: 8.9. Cuartil: Q1
(1er decil)
Marcos A., León C., Moreno-Fernández M., Castro-Rubio F., Garrido-Matilla L., Nozal L., Ambrosio E., Crego A.L.. Untargeted metabolomic study by liquid chromatography–mass spectrometry in brain tissues on the effects of combined cocaine and ethanol self-administration in male and female young rats. Journal of Chromatography A. 5 July 2023. DOI: 10.1016/j.chroma.2023.464047.
Impacto: 3.8. Cuartil: Q1
Huidobro-López B., León C., López-Heras I., Martínez-Hernández V., Nozal L., Crego A.L., de Bustamante I.. Untargeted metabolomic analysis to explore the impact of soil amendments in a non-conventional wastewater treatment. Science of the Total Environment. 20 April 2023. DOI: 10.1016/j.scitotenv.2023.161890.
Impacto: 8.2. Cuartil: Q1
(1er decil)
Chacón M., Vázquez N., Alonso-Alonso S., Persinal-Medina M., Llames S., Pevida M., Alcalde I., Merayo-Lloves J., Meana Á.. Improved Tool for Predicting Skin Irritation on Reconstructed Human Epidermis Models Based on Electrochemical Impedance Spectroscopy. Biosensors. February 2023. DOI: 10.3390/bios13020162.
Impacto: 4.9. Cuartil: Q1
Prieto-Fernandez L., Villaronga M.d.l.A., Hermida-Prado F., Hijazi M., Montoro-Jimenez I., Pevida M., Llames S., Rodrigo J.P., Cutillas P., Calvo F., Garcia-Pedrero J.M., Alvarez-Teijeiro S.. Driving role of head and neck cancer cell secretome on the invasion of stromal fibroblasts: Mechanistic insights by phosphoproteomics. Biomedicine and Pharmacotherapy. February 2023. DOI: 10.1016/j.biopha.2022.114176.
Impacto: 6.9. Cuartil: Q1
(1er decil)
Ma T., Méndez-Merino D., Uría-Regojo G., Sánchez-Fernández C., Giner-Sánchez L., Guerrero-Aspizua S., Quílez-López C., Rodríguez-Patón A.. BioBlocksLab: A portable DIY Bio Lab using BioBlocks language. Methods. February 2023. DOI: 10.1016/j.ymeth.2023.01.001.
Impacto: 4.2. Cuartil: Q1
Lozano Í., Bangueses R., Rodríguez I., Pevida M., Rodríguez-Aguilar R., Rodríguez D., Espasandín-Arias M., Llames S., Meana Á., Suárez A., Rodríguez-Carrio J.. In-stent restenosis is associated with proliferative skin healing and specific immune and endothelial cell profiles: results from the RACHEL trial. Frontiers in Immunology. 2023. DOI: 10.3389/fimmu.2023.1138247.
Impacto: 5.7. Cuartil: Q1
García M., Bonafont J., Martínez-Palacios J., Xu R., Turchiano G., Svensson S., Thrasher A.J., Larcher F., Del Rio M., Hernández-Alcoceba R., Garín M.I., Mencía Á., Murillas R.. Preclinical model for phenotypic correction of dystrophic epidermolysis bullosa by in vivo CRISPR-Cas9 delivery using adenoviral vectors. Molecular Therapy Methods and Clinical Development. 8 December 2022. DOI: 10.1016/j.omtm.2022.09.005.
Martín C., Ordiales H., Vázquez F., Pevida M., Rodríguez D., Merayo J., Vázquez F., García B., Quirós L.M.. Bacteria associated with acne use glycosaminoglycans as cell adhesion receptors and promote changes in the expression of the genes involved in their biosynthesis. BMC Microbiology. December 2022. DOI: 10.1186/s12866-022-02477-2.
Impacto: 4.2. Cuartil: Q2
Segura-Bedmar I., Camino-Perdones D., Guerrero-Aspizua S.. Exploring deep learning methods for recognizing rare diseases and their clinical manifestations from texts. BMC Bioinformatics. December 2022. DOI: 10.1186/s12859-022-04810-y.
Impacto: 3.0. Cuartil: Q2
Fernández-Vega-Cueto L., Persinal-Medina M., Vázquez N., Chacón M., Alfonso-Bartolozzi B., Alonso-Alonso S., Sánchez T., Berisa-Prado S., Martínez-López L.M., Merayo-Lloves J., Meana Á.. A Simple, Safe, and Effective Method for Preparing Autologous Bio-Based Fibrin Glue for Ophthalmic Use. Pharmaceutics. November 2022. DOI: 10.3390/pharmaceutics14112325.
Impacto: 5.4. Cuartil: Q1
Bort A., G. Sánchez B., León C., Nozal L., Mora-Rodríguez J.M., Castro F., Crego A.L., Díaz-Laviada I.. Metabolic fingerprinting of chemotherapy-resistant prostate cancer stem cells. An untargeted metabolomic approach by liquid chromatography-mass spectrometry. Frontiers in Cell and Developmental Biology. 17 October 2022. DOI: 10.3389/fcell.2022.1005675.
Impacto: 5.5. Cuartil: Q1
Bischof J., March O.P., Liemberger B., Haas S.A., Hainzl S., Petković I., Leb-Reichl V., Illmer J., Korotchenko E., Klausegger A., Hoog A., Binder H.M., Garcia M., Duarte B., Strunk D., Larcher F., Reichelt J., Guttmann-Gruber C., Wally V., Hofbauer J.P., Bauer J.W., Cathomen T., Kocher T., Koller U.. Paired nicking-mediated COL17A1 reframing for junctional epidermolysis bullosa. Molecular Therapy. 3 August 2022. DOI: 10.1016/j.ymthe.2022.04.020.
Impacto: 12.4. Cuartil: Q1
(1er decil)
Chacón-Solano E., León C., Carretero M., García M., Sánchez-Domínguez R., Quero F., Méndez-Jiménez E., Bonafont J., Ruiz-Mezcua B., Escámez M.J., Larcher F., del Río M.. Mechanistic interrogation of mutation-independent disease modulators of RDEB identifies the small leucine-rich proteoglycan PRELP as a TGF-β antagonist and inhibitor of fibrosis. Matrix Biology. August 2022. DOI: 10.1016/j.matbio.2022.06.007.
Impacto: 6.9. Cuartil: Q1
de Arriba M.d.C., Fernández G., Chacón-Solano E., Mataix M., Martínez-Santamaría L., Illera N., Carrión-Marchante R., Martín M.E., Larcher F., González V.M., Del Río M., Carretero M.. FPR2 DNA Aptamers for Targeted Therapy of Wound Repair. Journal of Investigative Dermatology. August 2022. DOI: 10.1016/j.jid.2021.12.026.
Impacto: 6.5. Cuartil: Q1
(1er decil)
Chacón M., Vázquez N., Persinal-Medina M., Alonso-Alonso S., Alcalde I., Merayo-Lloves J., Meana Á.. In-house performance assessment of 3D QobuR-Reconstructed Human Cornea-Like Epithelium (RhCE) for the evaluation of eye hazard. Toxicology in Vitro. August 2022. DOI: 10.1016/j.tiv.2022.105390.
Impacto: 3.2. Cuartil: Q2
Chacón M., Sánchez M., Vázquez N., Persinal-Medina M., Alonso-Alonso S., Baamonde B., Alfonso J.F., Fernández-Vega-Cueto L., Merayo-Lloves J., Meana Á.. Impedance-based non-invasive assay for ocular damage prediction on in vitro 3D reconstructed human corneal epithelium. Bioelectrochemistry. August 2022. DOI: 10.1016/j.bioelechem.2022.108129.
Impacto: 5.0. Cuartil: Q1
Gostyński A., Diercks G.F.H., Escamez M.J., Chandran N.S., de Lucas R., Garcia-Martin A., Del Rio M., Bremer J., Bolling M.C., Meana A., Llames S.G., Schmidt E., Ludwig R., Jonkman M.F., Pas H.H., Pasmooij A.M.G.. Natural Occurrence of Autoantibodies against Basement Membrane Proteins in Epidermolysis Bullosa. Journal of Investigative Dermatology. July 2022. DOI: 10.1016/j.jid.2021.10.030.
Impacto: 6.5. Cuartil: Q1
(1er decil)
Ordiales H., Vázquez-López F., Pevida M., Vázquez-Losada B., Vázquez F., Quirós L.M., Martín C.. Adherence of Candida albicans and Malassezia Species to Skin Cells Induces Changes in the Expression of Genes Responsible for Heparan and Chondroitin Sulfate Chain Synthesis. Actas Dermo-Sifiliograficas. 1 July 2022. DOI: 10.1016/j.ad.2021.11.010.
Salinas F., Robla D., Meana Á., Pevida M., Martinez Magide G., Sánchez Nuño C., Martín Suárez L., Astudillo González A., García E., Junquera L.. Novel technique of development of human derived acellular dermal matrix. Cell and Tissue Banking. June 2022. DOI: 10.1007/s10561-021-09954-4.
Impacto: 1.5. Cuartil: Q4
Luque J., Mendes I., Gómez B., Morte B., López de Heredia M., Herreras E., Corrochano V., Bueren J., Gallano P., Artuch R., Fillat C., Pérez-Jurado L.A., Montoliu L., Carracedo Á., Millán J.M., Webb S.M., Palau F., Aguado C., Aguado C., Aguilera P., Albiñana V., Alías L., Almoguera B., Alonso J., Alonso-Ferreira V., Alvarez-Mora M.I., Antiñolo G., Arbones M.L., Arenas J., Arjona E., Armangue T., Armstrong J., Arnedo M., Masó A.A., Avila-Fernandez A., Ayuso C., Badell I., Badenas C., Baeza M.L., Baiget M., Balcells S., Ballesta-Martínez M.J., Barahona M.J., Barros F., Bartoccioni P.C., Pilar Bayona-Bafaluy M., Benito Sanz S., Bernabéu C., Bernal S., Blanco-Kelly F., Blázquez A., Bodoy S., Bogliolo M., Borralleras C., Borrego S., Botella L.M., Bou de Pieri F., Bovolenta P., Bravo-Gil N., Brea A., Bueno-Lozano G., Bueren J., Bustamante A., Caballero T., Camacho-Macorra C., Cámara Y., Camats-Tarruella N., Campos Barros Á., Campuzano V., Cantarero L., Cantó J., Caparrós-Martín J., Cardellach F., Carmona R., Carrera C., Carretero M., Casado M., Casado J., Casasnovas C., Cascón A., Casino P., Castaño L., Castilla-Vallmanya L., Catala A., Luisa Cayuela M., Cediel R., Cervera J., Codina-Solà M., Contreras J., Cormand B., Corominas R., Corral J., Cortés-Rodríguez A., Corton M., Costa-Roger M., Cozar M., Crespo I., Crispi F.. CIBERER: Spanish national network for research on rare diseases: A highly productive collaborative initiative. Clinical Genetics. 01 May-June 2022. DOI: 10.1111/cge.14113.
Impacto: 3.5. Cuartil: Q2
Persinal‐medina M., Llames S., Chacón M., Vázquez N., Pevida M., Alcalde I., Alonso‐alonso S., Martínez‐lópez L.M., Merayo‐lloves J., Meana Á.. Polymerizable Skin Hydrogel for Full Thickness Wound Healing. International Journal of Molecular Sciences. May-1 2022. DOI: 10.3390/ijms23094837.
Impacto: 5.6. Cuartil: Q1
Martínez-Santamaría L., Maseda R., De Arriba M.D.C., Membrilla J.A., Sigüenza A.I., Mascías J., García M., Quintana L., Esteban-Rodríguez I., Hernández-Fernández C.P., Illera N., Duarte B., Guerrero-Aspizúa S., Woodley D.T., Del Río M., De Lucas R., Larcher F., Escámez M.J.. Evaluation of Systemic Gentamicin as Translational Readthrough Therapy for a Patient With Epidermolysis Bullosa Simplex With Muscular Dystrophy Owing to PLEC1 Pathogenic Nonsense Variants. JAMA Dermatology. April 2022. DOI: 10.1001/jamadermatol.2022.0112.
Impacto: 10.9. Cuartil: Q1
(1er decil)
O’Keeffe Ahern J., Lara-Sáez I., Zhou D., Murillas R., Bonafont J., Mencía Á., García M., Manzanares D., Lynch J., Foley R., Xu Q., Sigen A., Larcher F., Wang W.. Non-viral delivery of CRISPR–Cas9 complexes for targeted gene editing via a polymer delivery system. Gene Therapy. April 2022. DOI: 10.1038/s41434-021-00282-6.
Impacto: 5.1. Cuartil: Q1
Almeida J.I., Tenreiro M.F., Martinez-Santamaria L., Guerrero-Aspizua S., Gisbert J.P., Alves P.M., Serra M., Baptista P.M.. Hallmarks of the human intestinal microbiome on liver maturation and function. Journal of Hepatology. March 2022. DOI: 10.1016/j.jhep.2021.10.015.
Impacto: 25.7. Cuartil: Q1
(1er decil)
Ballester A., Guijarro A., Bravo B., Hernández J., Murillas R., Gallego M.I., Ballester S.. Hedgehog Signalling Modulates Immune Response and Protects against Experimental Autoimmune Encephalomyelitis. International Journal of Molecular Sciences. March-2 2022. DOI: 10.3390/ijms23063171.
Impacto: 5.6. Cuartil: Q1
Romano V., Kazaili A., Pagano L., Gadhvi K.A., Titley M., Steger B., Fernández-Vega-Cueto L., Meana A., Merayo-Lloves J., Diego P., Akhtar R., Levis H.J., Ferrari S., Kaye S.B., Parekh M.. Eye bank versus surgeon prepared DMEK tissues: Influence on adhesion and re-bubbling rate. British Journal of Ophthalmology. 1 February 2022. DOI: 10.1136/bjophthalmol-2020-317608.
Impacto: 4.1. Cuartil: Q1
Martínez-deMiguel C., Segura-Bedmar I., Chacón-Solano E., Guerrero-Aspizua S.. The RareDis corpus: A corpus annotated with rare diseases, their signs and symptoms. Journal of Biomedical Informatics. January 2022. DOI: 10.1016/j.jbi.2021.103961.
Impacto: 4.5. Cuartil: Q2
Ramos-Espinosa O., Mata-Espinosa D., Francisco-Cruz A., López-Torres M.O., Hernández-Bazán S., Barrios-Payán J., Marquina-Castillo B., Carretero M., del Río M., Hernández-Pando R.. Immunotherapeutic effect of adenovirus encoding antimicrobial peptides in experimental pulmonary tuberculosis. Journal of Leukocyte Biology. November 2021. DOI: 10.1002/JLB.4MA0920-627R.
Impacto: 6.011. Cuartil: Q2
Maseda Pedrero R., Quintana Castanedo L., Pérez Conde I., Jiménez González M., Escámez Toledano M.J., de Lucas Laguna R.. Epidermolysis Bullosa in Spain: Observational Study of a Cohort of Patients Treated in a National Referral Center. Actas Dermo-Sifiliograficas. October 2021. DOI: 10.1016/j.ad.2021.04.006.
Potrony M., Haddad T.S., Tell-Martí G., Gimenez-Xavier P., Leon C., Pevida M., Mateu J., Badenas C., Carrera C., Malvehy J., Aguilera P., Llames S., Escámez M.J., Puig-Butillé J.A., del Río M., Puig S.. DNA Repair and Immune Response Pathways Are Deregulated in Melanocyte-Keratinocyte Co-cultures Derived From the Healthy Skin of Familial Melanoma Patients. Frontiers in Medicine. 1 October 2021. DOI: 10.3389/fmed.2021.692341.
Impacto: 5.058. Cuartil: Q2
Peña G.d.l., Gallego L., Redondo L.M., Junquera L., Doval J.F., Meana Á.. Comparative analysis of plasma-derived albumin scaffold, alveolar osteoblasts and synthetic membrane in critical mandibular bone defects: An experimental study on rats. Journal of Biomaterials Applications. September 2021. DOI: 10.1177/0885328221999824.
Impacto: 2.712. Cuartil: Q3
Berisa-Prado S., Vázquez N., Chacón M., Persinal-Medina M., Alonso-Alonso S., Baamonde B., Alfonso J.F., Fernández-Vega-cueto L., Merayo-Lloves J., Meana Á.. Mini cleanroom for the manufacture of advanced therapy medicinal products (Atmp): Bioengineered corneal epithelium. Pharmaceutics. August 2021. DOI: 10.3390/pharmaceutics13081282.
Impacto: 6.525. Cuartil: Q1
Hugo Montes A., Valle-Garay E., Martin G., Collazos J., Alvarez V., Meana A., Pérez-Is L., Carton J.A., Taboada F., Asensi V.. The TNF-α (–238 G/A) polymorphism could protect against development of severe sepsis. Innate Immunity. July 2021. DOI: 10.1177/17534259211036186.
Impacto: 2.951. Cuartil: Q3
Ordiales H., Vázquez-López F., Pevida M., Vázquez-Losada B., Vázquez F., Quirós L.M., Martín C.. Glycosaminoglycans Are Involved in the Adhesion of Candida albicans and Malassezia Species to Keratinocytes But Not to Dermal Fibroblasts. Actas Dermo-Sifiliograficas. July 2021. DOI: 10.1016/j.ad.2021.02.001.
Bonafont J., Mencía A., Chacón-Solano E., Srifa W., Vaidyanathan S., Romano R., Garcia M., Hervás-Salcedo R., Ugalde L., Duarte B., Porteus M.H., Del Rio M., Larcher F., Murillas R.. Correction of recessive dystrophic epidermolysis bullosa by homology-directed repair-mediated genome editing. Molecular Therapy. 2 June 2021. DOI: 10.1016/j.ymthe.2021.02.019.
Impacto: 12.91. Cuartil: Q1
(1er decil)
Sánchez-ávila R.M., Vázquez N., Chacón M., Persinal-Medina M., Brea-Pastor A., Berisa-Prado S., Fernández-Vega-cueto L., Anitua E., Meana Á., Merayo-Lloves J.. Fibrin-plasma rich in growth factors membrane for the treatment of a rabbit alkali-burn lesion. International Journal of Molecular Sciences. 1 June 2021. DOI: 10.3390/ijms22115564.
Impacto: 6.208. Cuartil: Q1
Somolinos F.J., León C., Guerrero-Aspizua S.. Drug repurposing using biological networks. Processes. June 2021. DOI: 10.3390/pr9061057.
Impacto: 3.352. Cuartil: Q2
Nogacka A.M., de los Reyes-Gavilán C.G., Martínez-Faedo C., Ruas-Madiedo P., Suarez A., Mancabelli L., Ventura M., Cifuentes A., León C., Gueimonde M., Salazar N.. Impact of Extreme Obesity and Diet-Induced Weight Loss on the Fecal Metabolome and Gut Microbiota. Molecular Nutrition and Food Research. March 2021. DOI: 10.1002/mnfr.202000030.
Impacto: 6.575. Cuartil: Q1
Segura-Bedmar I., Ruz L., Guerrero-Aspizua S.. Evaluation of a transformer model applied to the task of text summarization in different domains. Procesamiento del Lenguaje Natural. 1 March 2021. DOI: 10.26342/2021-66-2.
Persinal-Medina M., Llames S., Vázquez N., Chacón M., Acebes-Huerta A., Uribe E., Alonso-Alonso S., Fernández-Vega González C., Baamonde B., Quirós L., Merayo-Lloves J., Meana . Xeno-free approach for the expansion of human adipose derived mesenchymal stem cells for ocular therapies. Experimental Eye Research. January 2021. DOI: 10.1016/j.exer.2020.108358.
Impacto: 3.77. Cuartil: Q2
Leon C., Garda-Garda F., Llames S., Garda-Perez E., Carretero M., Del Carmen Arriba M., Dopazo J., Del Rfo M., Jose Escamez M., Martrnez-Santamaria L.. Transcriptomic analysis of a diabetic skin-humanized mouse model dissects molecular pathways underlying the delayed wound healing response. Genes. January 2021. DOI: 10.3390/genes12010047.
Impacto: 4.141. Cuartil: Q2
Maseda R., Martínez-Santamaría L., Sacedón R., Butta N., Arriba M.d.C.d., García-Barcenilla S., García M., Illera N., Pérez-Conde I., Carretero M., Jiménez E., Melen G., Borobia A.M., Jiménez-Yuste V., Vicente Á., del Río M., de Lucas R., Escámez M.J.. Beneficial Effect of Systemic Allogeneic Adipose Derived Mesenchymal Cells on the Clinical, Inflammatory and Immunologic Status of a Patient With Recessive Dystrophic Epidermolysis Bullosa: A Case Report. Frontiers in Medicine. 26 November 2020. DOI: 10.3389/fmed.2020.576558.
Leon C.. Introduction to Omics Data Treatment, System Biology and Foodomics. Comprehensive Foodomics. 12 November 2020. DOI: 10.1016/B978-0-12-816395-5.00004-6.
Aguado T., García M., García A., Ferrer-Mayorga G., Martínez-Santamaría L., Del Río M., Botella L.M., Sánchez-Puelles J.M.. Raloxifene and n-Acetylcysteine Ameliorate TGF-Signalling in Fibroblasts from Patients with Recessive Dominant Epidermolysis Bullosa. Cells. 16 September 2020. DOI: 10.3390/cells9092108.
Impacto: 6.6. Cuartil: Q2
Gálvez V., Chacón-Solano E., Bonafont J., Mencía Á., Di W.L., Murillas R., Llames S., Vicente A., Del Rio M., Carretero M., Larcher F.. Efficient CRISPR-Cas9-Mediated Gene Ablation in Human Keratinocytes to Recapitulate Genodermatoses: Modeling of Netherton Syndrome. Molecular Therapy Methods and Clinical Development. 11 September 2020. DOI: 10.1016/j.omtm.2020.05.031.
Impacto: 6.698. Cuartil: Q1
Zambrano-Andazol I., Vázquez N., Chacón M., Sánchez-Avila R.M., Persinal M., Blanco C., González Z., Menéndez R., Sierra M., Fernández-Vega Á., Sánchez T., Merayo-Lloves J., Meana Á.. Reduced graphene oxide membranes in ocular regenerative medicine. Materials Science and Engineering C. September 2020. DOI: 10.1016/j.msec.2020.111075.
Impacto: 7.328. Cuartil: Q1
Martínez-Santamaría L., Cárcamo C., García-Pardo L., García-Arranz M., Melen G., Guerrero-Aspizua S., Llanos L., Río M.D., García-Olmo D., Escámez M.J.. Combined adipose mesenchymal stromal cell advanced therapy resolved a recalcitrant leg ulcer in an 85-year-old patient. Regenerative Medicine. September 2020. DOI: 10.2217/rme-2020-0139.
Impacto: 3.806. Cuartil: Q2
Nicolás-Sáenz L., Guerrero-Aspizua S., Pascau J., Muñoz-Barrutia A.. Nonlinear image registration and pixel classification pipeline for the study of tumor heterogeneity maps. Entropy. September 2020. DOI: 10.3390/E22090946.
Impacto: 2.524. Cuartil: Q2
Guerrero-Aspizua S., Carretero M., Conti C.J., Del Río M.. The importance of immunity in the development of reliable animal models for psoriasis and atopic dermatitis. Immunology and Cell Biology. 1 September 2020. DOI: 10.1111/imcb.12365.
Impacto: 5.126. Cuartil: Q2
Gallego L., Junquera L., Garciá-Consuegra L., Martinez A., Meana Á.. Regeneration of mandibular osteoradionecrosis with autologous cross-linked serum albumin scaffold. Regenerative Medicine. July 2020. DOI: 10.2217/rme-2020-0042.
Impacto: 3.806. Cuartil: Q2
Chacón M., Vázquez N., Persinal-Medina M., Alonso-Alonso S., Pevida M., Llames S., Baamonde B., Quiros L., Merayo-Lloves J., Meana Á.. Development of an in-house reconstructed human epidermis model as an alternative method in skin corrosion assessment. Toxicology in Vitro. June 2020. DOI: 10.1016/j.tiv.2020.104779.
Impacto: 3.5. Cuartil: Q2
Moreno-Oyervides A., Aguilera-Morillo M.C., Larcher F., Krozer V., Acedo P.. Advanced Statistical Techniques for Noninvasive Hyperglycemic States Detection in Mice Using Millimeter-Wave Spectroscopy. IEEE Transactions on Terahertz Science and Technology. May 2020. DOI: 10.1109/TTHZ.2020.2967236.
Impacto: 3.274. Cuartil: Q2
Ballesteros-Vivas D., Alvarez-Rivera G., León C., Morantes S.J., Ibánez E., Parada-Alfonso F., Cifuentes A., Valdés A.. Foodomics evaluation of the anti-proliferative potential of Passiflora mollissima seeds. Food Research International. April 2020. DOI: 10.1016/j.foodres.2019.108938.
Impacto: 6.475. Cuartil: Q1
(1er decil)
Guerrero-Aspizua S., González-Masa A., Conti C.J., García M., Chacón-Solano E., Larcher F., Del Río M.. Humanization of tumor stroma by tissue engineering as a tool to improve squamous cell carcinoma xenograft. International Journal of Molecular Sciences. 2 March 2020. DOI: 10.3390/ijms21061951.
Impacto: 5.923. Cuartil: Q1
Has C., Liu L., Bolling M.C., Charlesworth A.V., El Hachem M., Escámez M.J., Fuentes I., Büchel S., Hiremagalore R., Pohla-Gubo G., van den Akker P.C., Wertheim-Tysarowska K., Zambruno G.. Clinical practice guidelines for laboratory diagnosis of epidermolysis bullosa. British Journal of Dermatology. 1 March 2020. DOI: 10.1111/bjd.18128.
Impacto: 9.302. Cuartil: Q1
(1er decil)
Quílez C., de Aranda Izuzquiza G., García M., López V., Montero A., Valencia L., Velasco D.. Bioprinting for Skin. Methods in Molecular Biology. 2020. DOI: 10.1007/978-1-0716-0520-2_14.
León C.. Foodomics evaluation of genetically modified organisms. Chemical Analysis of Food: Techniques and Applications, Second Edition. 1 January 2020. DOI: 10.1016/B978-0-12-813266-1.00015-2.
Sánchez Ibáñez J., Vilarrodona Serrat A., Seoane Pillado T., Rodriguez Aierbe C., Villalba Montoro R., Calvo Benito J., Pevida Lopez M., Fernández Paneque S., Vuelta Lopez E., Martínez Lorenzo M.J., González Romero M., Cañizares Castellanos A., Sauleda Oliveras S.. Evaluation of occult hepatitis B infection in tissue donors: a multicenter analysis in Spain. Cell and Tissue Banking. 1 December 2019. DOI: 10.1007/s10561-019-09784-5.
Impacto: 1.149. Cuartil: Q4
Ballesteros-Vivas D., Alvarez-Rivera G., León C., Morantes S.J., Ibánez E., Parada-Alfonso F., Cifuentes A., Valdés A.. Anti-proliferative bioactivity against HT-29 colon cancer cells of a withanolides-rich extract from golden berry (Physalis peruviana L.) calyx investigated by Foodomics. Journal of Functional Foods. December 2019. DOI: 10.1016/j.jff.2019.103567.
Impacto: 3.701. Cuartil: Q1
Castelo B., Viñal D., Maseda R., Ostios L., Sánchez D., García-Salvatierra B., Escámez M.J., Martínez-Santamaría L., Del Río M., Mora-Rillo M., Vilches Y., Beato M.J., López Gutiérrez J.C., Romero N., Santos C., Miranda J., de Lucas R.. Epidemiology and natural history of cutaneous squamous cell carcinoma in recessive dystrophic epidermolysis bullosa patients: 20 years’ experience of a reference centre in Spain. Clinical and Translational Oncology. 1 November 2019. DOI: 10.1007/s12094-019-02073-3.
Impacto: 2.737. Cuartil: Q3
Pérez-Is L., Ocaña M.G., Montes A.H., Carton J.A., Álvarez V., Meana Á., Fierer J., Valle-Garay E., Asensi V.. The N125S polymorphism in the cathepsin G gene (rs45567233) is associated with susceptibility to osteomyelitis in a Spanish population. PLoS ONE. 1 October 2019. DOI: 10.1371/journal.pone.0220022.
Impacto: 2.74. Cuartil: Q2
Chacón-Solano E., León C., Díaz F., García-García F., García M., Escámez M.J., Guerrero-Aspizua S., Conti C.J., Mencía , Martínez-Santamaría L., Llames S., Pévida M., Carbonell-Caballero J., Puig-Butillé J.A., Maseda R., Puig S., de Lucas R., Baselga E., Larcher F., Dopazo J., del Río M.. Fibroblast activation and abnormal extracellular matrix remodelling as common hallmarks in three cancer-prone genodermatoses. British Journal of Dermatology. 1 September 2019. DOI: 10.1111/bjd.17698.
Impacto: 7.0. Cuartil: Q1
(1er decil)
Guerrero-Aspizua S., Conti C.J., Escamez M.J., Castiglia D., Zambruno G., Youssefian L., Vahidnezhad H., Requena L., Itin P., Tadini G., Yordanova I., Martin L., Uitto J., Has C., Del Rio M.. Assessment of the risk and characterization of non-melanoma skin cancer in Kindler syndrome: study of a series of 91 patients. Orphanet journal of rare diseases. 24 July 2019. DOI: 10.1186/s13023-019-1158-6.
Impacto: 3.523. Cuartil: Q2
Lwin S.M., Syed F., Di W.L., Kadiyirire T., Liu L., Guy A., Petrova A., Abdul-Wahab A., Reid F., Phillips R., Elstad M., Georgiadis C., Aristodemou S., Lovell P.A., McMillan J.R., Mee J., Miskinyte S., Titeux M., Ozoemena L., Pramanik R., Serrano S., Rowles R., Maurin C., Orrin E., Martinez-Queipo M., Rashidghamat E., Tziotzios C., Onoufriadis A., Chen M., Chan L., Farzaneh F., Rio M.D., Tolar J., Bauer J.W., Larcher F., Antoniou M.N., Hovnanian A., Thrasher A.J., Mellerio J.E., Qasim W., McGrath J.A.. Safety and early efficacy outcomes for lentiviral fibroblast gene therapy in recessive dystrophic epidermolysis bullosa. JCI Insight. 6 June 2019. DOI: 10.1172/jci.insight.126243.
Bonafont J., Mencía Á., García M., Torres R., Rodríguez S., Carretero M., Chacón-Solano E., Modamio-Høybjør S., Marinas L., León C., Escamez M.J., Hausser I., Del Río M., Murillas R., Larcher F.. Clinically Relevant Correction of Recessive Dystrophic Epidermolysis Bullosa by Dual sgRNA CRISPR/Cas9-Mediated Gene Editing. Molecular Therapy. 8 May 2019. DOI: 10.1016/j.ymthe.2019.03.007.
Impacto: 8.986. Cuartil: Q1
(1er decil)
Chacón M., Vázquez N., Berisa S., Persinal M., Sánchez M., Baamonde B., Alfonso J.F., Fernández-Vega Cueto L., Merayo-Lloves J., Meana Á.. QobuR – A new in vitro human corneal epithelial model for preclinical drug screening. European Journal of Pharmaceutics and Biopharmaceutics. March 2019. DOI: 10.1016/j.ejpb.2019.01.023.
Impacto: 4.604. Cuartil: Q1
Barreda L., Marcet I., Llames S., Pevida M., García-Pérez E., Meana Á., Rendueles M., Díaz M.. Human plasma gels: Their preparation and rheological characterization for cell culture applications in tissue engineering. Journal of the Mechanical Behavior of Biomedical Materials. January 2019. DOI: 10.1016/j.jmbbm.2018.09.015.
Impacto: 3.372. Cuartil: Q2
Moreno-Oyervides A., Martín-Mateos P., Aguilera-Morillo M.C., Ulisse G., Arriba M.C., Durban M., Del Rio M., Larcher F., Krozer V., Acedo P.. Early, non-invasive sensing of sustained hyperglycemia in mice using millimeter-wave spectroscopy. Sensors (Switzerland). 2019. DOI: 10.3390/s19153347.
Impacto: 3.275. Cuartil: Q1
Martínez-Periñán E., Sánchez-Tirado E., González-Cortés A., Barderas R., Sánchez-Puelles J.M., Martínez-Santamaría L., Campuzano S., Yáñez-Sedeño P., Pingarrón J.M.. Amperometric determination of endoglin in human serum using disposable immunosensors constructed with poly(pyrrolepropionic) acid-modified electrodes. Electrochimica Acta. 1 December 2018. DOI: 10.1016/j.electacta.2018.10.015.
Impacto: 5.383. Cuartil: Q1
Moreno-Overvides A., Martin-Mateos P., Aguilera-Morillo M.C., Ulisse G., Larcher F., Krozer V., Acedo P.. Non-invasive Detection and Monitoring of Sustained Glycemic Fluctuations using Mm-Wave Spectroscopy. 2018 48th European Microwave Conference, EuMC 2018. 20 November 2018. DOI: 10.23919/EuMC.2018.8541413.
Benati D., Miselli F., Cocchiarella F., Patrizi C., Carretero M., Baldassarri S., Ammendola V., Has C., Colloca S., Del Rio M., Larcher F., Recchia A.. CRISPR/Cas9-Mediated In Situ Correction of LAMB3 Gene in Keratinocytes Derived from a Junctional Epidermolysis Bullosa Patient. Molecular Therapy. 7 November 2018. DOI: 10.1016/j.ymthe.2018.07.024.
Impacto: 8.402. Cuartil: Q1
(1er decil)
Fillat C., Del Río M., Martínez-Santamaría L., Bueren J.A.. Advanced therapies for rare diseases. Arbor. July-September 2018. DOI: 10.3989/arbor.2018.789n3009.
Mencía Á., Chamorro C., Bonafont J., Duarte B., Holguin A., Illera N., Llames S.G., Escámez M.J., Hausser I., Del Río M., Larcher F., Murillas R.. Deletion of a Pathogenic Mutation-Containing Exon of COL7A1 Allows Clonal Gene Editing Correction of RDEB Patient Epidermal Stem Cells. Molecular Therapy Nucleic Acids. 1 June 2018. DOI: 10.1016/j.omtn.2018.01.009.
Impacto: 5.919. Cuartil: Q1
Knöpfel N., Noguera-Morel L., Hernández-Martin A., García-Martin A., García M., Mencía Á., Pedrero R.M., de Lucas R., Escámez M.J., Torrelo A.. Identical COL71A1 heterozygous mutations resulting in different dystrophic epidermolysis bullosa phenotypes. Pediatric Dermatology. March/April 2018. DOI: 10.1111/pde.13367.
Impacto: 1.178. Cuartil: Q3
Sánchez-Jimeno C., Escámez M.J., Ayuso C., Trujillo-Tiebas M.J., del Río M.. Genetic diagnosis of epidermolysis bullosa: recommendations from an expert Spanish research group. Actas Dermo-Sifiliograficas. March 2018. DOI: 10.1016/j.ad.2017.08.008.
Chacón-Solano E., Guerrero-Aspizua S., Martínez-Santamaría L., Del Río M., Larcher F.. Organotypic and humanized animal models of genodermatoses. Skin Tissue Models. 2018. DOI: 10.1016/B978-0-12-810545-0.00004-8.
León C., Cifuentes A., Valdés A.. Foodomics Applications. Comprehensive Analytical Chemistry. 1 January 2018. DOI: 10.1016/bs.coac.2018.06.008.
Dornuf F., Martín-Mateos P., Duarte B., Hils B., Bonilla-Manrique O.E., Larcher F., Acedo P., Krozer V.. Classification of skin phenotypes caused by diabetes mellitus using complex scattering parameters in the millimeter-wave frequency range. Scientific Reports. 1 December 2017. DOI: 10.1038/s41598-017-06034-0.
Impacto: 4.122. Cuartil: Q1
Hainzl S., Peking P., Kocher T., Murauer E.M., Larcher F., Del Rio M., Duarte B., Steiner M., Klausegger A., Bauer J.W., Reichelt J., Koller U.. COL7A1 Editing via CRISPR/Cas9 in Recessive Dystrophic Epidermolysis Bullosa. Molecular Therapy. 1 November 2017. DOI: 10.1016/j.ymthe.2017.07.005.
Impacto: 7.008. Cuartil: Q1
(1er decil)
Valdés A., Cifuentes A., León C.. Foodomics evaluation of bioactive compounds in foods. TrAC - Trends in Analytical Chemistry. November 2017. DOI: 10.1016/j.trac.2017.06.004.
Impacto: 7.034. Cuartil: Q1
(1er decil)
Martin-Mateos P., Moreno-Oyervides A., Ulisse G., Duarte B., Dornuf F., Larcher F., Krozer V., Acedo P.. Monitoring the evolution of hyperglycemia in mice using mm-wave spectroscopy. International Conference on Infrared, Millimeter, and Terahertz Waves, IRMMW-THz. 12 October 2017. DOI: 10.1109/IRMMW-THz.2017.8066863.
Prado S.B., Riestra Ayora A.C., Fernández C.L., Rodríguez M.C., Merayo-Lloves J., Alfonso Sánchez J.F.. Topical Tacrolimus for Corneal Subepithelial Infiltrates Secondary to Adenoviral Keratoconjunctivitis. Cornea. 1 September 2017. DOI: 10.1097/ICO.0000000000001279.
Impacto: 2.464. Cuartil: Q2
Peking P., Koller U., Duarte B., Murillas R., Wolf S., Maetzig T., Rothe M., Kocher T., García M., Brachtl G., Schambach A., Larcher F., Reichelt J., Bauer J.W., Murauer E.M.. An RNA-targeted therapy for dystrophic epidermolysis bullosa. Nucleic Acids Research. 1 September 2017. DOI: 10.1093/nar/gkx669.
Impacto: 11.561. Cuartil: Q1
(1er decil)
Vázquez N., Rodríguez-Barrientos C.A., Aznar-Cervantes S.D., Chacón M., Cenis J.L., Riestra A.C., Sánchez-Avila R.M., Persinal M., Brea-Pastor A., Fernández-Vega Cueto L., Meana Á., Merayo-Lloves J.. Silk fibroin films for corneal endothelial regeneration: Transplant in a rabbit descemet membrane endothelial keratoplasty. Investigative Ophthalmology and Visual Science. July 2017. DOI: 10.1167/iovs.17-21797.
Impacto: 3.388. Cuartil: Q1
Latella M.C., Cocchiarella F., De Rosa L., Turchiano G., Gonçalves M.A.F.V., Larcher F., De Luca M., Recchia A.. Correction of Recessive Dystrophic Epidermolysis Bullosa by Transposon-Mediated Integration of COL7A1 in Transplantable Patient-Derived Primary Keratinocytes. Journal of Investigative Dermatology. 1 April 2017. DOI: 10.1016/j.jid.2016.11.038.
Impacto: 6.448. Cuartil: Q1
(1er decil)
Riestra A.C., Vazquez N., Chacon M., Berisa S., Sanchez-Avila R.M., Orive G., Anitua E., Meana A., Merayo-Lloves J.. Autologous method for ex vivo expansion of human limbal epithelial progenitor cells based on plasma rich in growth factors technology. Ocular Surface. 1 April 2017. DOI: 10.1016/j.jtos.2017.01.003.
Impacto: 5.53. Cuartil: Q1
(1er decil)
García M., Barrio R., García-Lavandeira M., Garcia-Rendueles A.R., Escudero A., Díaz-Rodríguez E., Gorbenko Del Blanco D., Fernández A., De Rijke Y.B., Vallespín E., Nevado J., Lapunzina P., Matre V., Hinkle P.M., Hokken-Koelega A.C.S., De Miguel M.P., Cameselle-Teijeiro J.M., Nistal M., Alvarez C.V., Moreno J.C.. The syndrome of central hypothyroidism and macroorchidism: IGSF1 controls TRHR and FSHB expression by differential modulation of pituitary TGFβ and Activin pathways. Scientific Reports. 6 March 2017. DOI: 10.1038/srep42937.
Impacto: 4.122. Cuartil: Q1
Cubo N., Garcia M., Del Cañizo J.F., Velasco D., Jorcano J.L.. 3D bioprinting of functional human skin: Production and in vivo analysis. Biofabrication. March 2017. DOI: 10.1088/1758-5090/9/1/015006.
Impacto: 6.838. Cuartil: Q1
(1er decil)
Chacón-Solano E., Guerrero-Aspizua S., Martínez-Santamaría L., Del Río M., Larcher F.. Organotypic and humanized animal models of genodermatoses. Skin Tissue Models. 1 January 2017. DOI: 10.1016/B978-0-12-810545-0.00004-8.