Investigadores
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Investigadores
Instituto contra la leucemia Josep Carreras (IJC). Barcelona.
Inmunoterapia Celular (células CAR)
Pablo MENÉNDEZ BRUJÁN
Investigador principal
Grupo de Investigación: Instituto contra la leucemia Josep Carreras (IJC). Barcelona.
Alba Rubio Gayarre
Investigador colaborador
Grupo de Investigación: Instituto contra la leucemia Josep Carreras (IJC). Barcelona.
Carla Panisello Aranda
Investigador colaborador
Grupo de Investigación: Instituto contra la leucemia Josep Carreras (IJC). Barcelona.
Clara Bueno Uroz
Investigador colaborador
Grupo de Investigación: Instituto contra la leucemia Josep Carreras (IJC). Barcelona.
LADY GIOVANNA ESPINOSA AROCA
Investigador colaborador
Grupo de Investigación: Instituto contra la leucemia Josep Carreras (IJC). Barcelona.
Maria Belen Lopez Millan
Investigador colaborador
Grupo de Investigación: Instituto contra la leucemia Josep Carreras (IJC). Barcelona.
Mercedes Guerrero Murillo
Investigador colaborador
Grupo de Investigación: Instituto contra la leucemia Josep Carreras (IJC). Barcelona.
Meritxell Vinyoles Vergés
Investigador colaborador
Grupo de Investigación: Instituto contra la leucemia Josep Carreras (IJC). Barcelona.
Néstor Tirado Cabrera
Investigador colaborador
Grupo de Investigación: Instituto contra la leucemia Josep Carreras (IJC). Barcelona.
Pedro Roda Navarro
Investigador colaborador
Grupo de Investigación: Instituto contra la leucemia Josep Carreras (IJC). Barcelona.
Talía Velasco Hernández
Investigador colaborador
Grupo de Investigación: Instituto contra la leucemia Josep Carreras (IJC). Barcelona.
VLADIMIR MULENS ARIAS
Investigador colaborador
Grupo de Investigación: Instituto contra la leucemia Josep Carreras (IJC). Barcelona.
Xu R., Martinez-Bosch N., Rivera-Hueto F., Mulens-Arias V., Rubio-Moscardo F., Javier Conesa J., Navarro P., Vicente R., Rivera-Gil P.. Validation of ZIP4 as a tumour-associated antigen for nanotargeting. Journal of Drug Targeting. 2025. DOI: 10.1080/1061186X.2024.2405711.
Impacto: 4.3. Cuartil: Q1
Petazzi P., Ventura T., Luongo F.P., McClafferty H., May A., Taylor H.A., Shipston M.J., Romanò N., Forrester L.M., Menendez P., Fidanza A.. A novel human pluripotent stem cell gene activation system identifies IGFBP2 as a mediator in the production of haematopoietic progenitors in vitro. eLife. 23 December 2024. DOI: 10.7554/eLife.94884.
Impacto: 6.4. Cuartil: Q1
(1er decil)
Justicia-Lirio P., Tristán-Manzano M., Maldonado-Pérez N., Barbero-Jiménez C., Cortijo-Gutiérrez M., Pavlovic K., Molina-Estevez F.J., Muñoz P., Hinckley-Boned A., Rodriguez-Madoz J.R., Prosper F., Griñán-Lison C., Navarro-Marchal S.A., Panisello C., Muñoz-Ballester J., González-Sierra P.A., Herrera C., Marchal J.A., Martín F.. First-in-class transactivator-free, doxycycline-inducible IL-18-engineered CAR-T cells for relapsed/refractory B cell lymphomas. Molecular Therapy Nucleic Acids. 10 December 2024. DOI: 10.1016/j.omtn.2024.102308.
Impacto: 6.5. Cuartil: Q1
Gómez-Morón Á., Alegre-Gómez S., Ramirez-Muñoz R., Hernaiz-Esteban A., Carrasco-Padilla C., Scagnetti C., Aguilar-Sopeña Ó., García-Gil M., Borroto A., Torres-Ruiz R., Rodriguez-Perales S., Sánchez-Madrid F., Martín-Cófreces N.B., Roda-Navarro P.. Human T-cell receptor triggering requires inactivation of Lim kinase-1 by Slingshot-1 phosphatase. Communications Biology. December 2024. DOI: 10.1038/s42003-024-06605-8.
Impacto: 5.2. Cuartil: Q1
Safi R., Mohsen-Kanson T., Kouzi F., El-Saghir J., Dermesrobian V., Zugasti I., Zibara K., Menéndez P., El Hajj H., El-Sabban M.. Direct Interaction Between CD34<sup>+</sup> Hematopoietic Stem Cells and Mesenchymal Stem Cells Reciprocally Preserves Stemness. Cancers. December 2024. DOI: 10.3390/cancers16233972.
Impacto: 4.5. Cuartil: Q1
Sjövall D., Ghosh S., Fernandez-Fuentes N., Velasco-Hernandez T., Hogmalm A., Menendez P., Hansson J., Guibentif C., Jaako P.. Defective ribosome assembly impairs leukemia progression in a murine model of acute myeloid leukemia. Cell Reports. 26 November 2024. DOI: 10.1016/j.celrep.2024.114864.
Impacto: 7.5. Cuartil: Q1
Guerrero-Murillo M., Rill-Hinarejos A., Trincado J.L., Bataller A., Ortiz-Maldonado V., Benítez-Ribas D., Español-Rego M., González-Navarro E.A., Martínez-Cibrián N., Marchese D., Martín-Martín L., Martín García-Sancho A., Rives S., Heyn H., Juan M., Urbano-Ispizúa Á., Delgado J., Orfao A., Mereu E., Bueno C., Menendez P.. Integrative single-cell multi-omics of CD19-CAR<sup>pos</sup> and CAR<sup>neg</sup> T cells suggest drivers of immunotherapy response in B cell neoplasias. Cell Reports Medicine. 19 November 2024. DOI: 10.1016/j.xcrm.2024.101803.
Impacto: 11.7. Cuartil: Q1
(1er decil)
Lopez-Millan B., Rubio-Gayarre A., Vinyoles M., Trincado J.L., Fraga M.F., Fernandez-Fuentes N., Guerrero-Murillo M., Martinez A., Velasco-Hernandez T., Falgàs A., Panisello C., Valcarcel G., Sardina J.L., López-Martí P., Javierre B.M., Del Valle-Pérez B., García de Herreros A., Locatelli F., Pieters R., Bardini M., Cazzaniga G., Rodríguez-Manzaneque J.C., Hanewald T., Marschalek R., Milne T.A., Stam R.W., Tejedor J.R., Menendez P., Bueno C.. NG2 is a target gene of MLL-AF4 and underlies glucocorticoid resistance in MLLr B-ALL by regulating NR3C1 expression. Blood. 7 November 2024. DOI: 10.1182/blood.2023022050.
Impacto: 21.0. Cuartil: Q1
(1er decil)
Panisello C., Aschero R., Martinez-Moreno A., Roca Ho H., Falgas A., González-Navarro E.A., Carabelli J., Pradenas E., Lázaro-Díez M., Prado J.G., Blanco J., Carrillo J., Juan M., Carcaboso Á.M., Bueno C., Menendez P.. NSGS mice humanized with cord blood mononuclear cells show sustained and functional myeloid-lymphoid representation with limited graft-versus-host disease. Journal for ImmunoTherapy of Cancer. 7 October 2024. DOI: 10.1136/jitc-2024-009198.
Impacto: 10.3. Cuartil: Q1
(1er decil)
Kodali S., Proietti L., Valcarcel G., López-Rubio A.V., Pessina P., Eder T., Shi J., Jen A., Lupión-Garcia N., Starner A.C., Bartels M.D., Cui Y., Sands C.M., Planas-Riverola A., Martínez A., Velasco-Hernandez T., Tomás-Daza L., Alber B., Manhart G., Mayer I.M., Kollmann K., Fatica A., Menendez P., Shishkova E., Rau R.E., Javierre B.M., Coon J., Chen Q., Van Nostrand E.L., Sardina J.L., Grebien F., Di Stefano B.. RNA sequestration in P-bodies sustains myeloid leukaemia. Nature Cell Biology. October 2024. DOI: 10.1038/s41556-024-01489-6.
Impacto: 17.3. Cuartil: Q1
(1er decil)
Bordoy A.E., Vallès X., Fernández-Náger J., Sánchez-Roig M., Fernández-Recio J., Saludes V., Noguera-Julian M., Blanco I., Martró E., Balcázar E.P., Díaz M.R., Encarnación R., Fuentes M., Gallego C., Pale A.M., Puig P., Moreno E.A., Puertolas A., Chouldry G., Sala I., Jiménez A.G., Armenteros B., Alvo J., Gómez S., Guillament M., Martínez D., Martin A., Moruno M.A., Parra N., Puig A., Rodríguez F.J., Sánchez M., Varoucha A.C., Moreno M., Martínez J., Huguet S., Sánchez A., Alonso T., Garcia M., Prat E., Aranda A., Arguelles M.J., Azqueta J., Cruz E., Egido R.M., Galvany R., Garcia B., González M., González V., Infante J.A., Latorre C., Márquez P., Muñoz I., Porras M., Ramos M., Escamilla M., Santalucía J., Riquelme M., Rastrollo L., Pedrerol M., Caraballo V., Fontan J., Verú M., Conill V., Soler L., Panisello Yagüe D., Casañ C., Clarà G., Giménez M., Guerrero-Murillo M., Cardona P.J., Marco A.. Analysis of a Large Severe Acute Respiratory Syndrome Coronavirus 2 (Alpha) Outbreak in a Catalan Prison Using Conventional and Genomic Epidemiology. Journal of Infectious Diseases. 15 August 2024. DOI: 10.1093/infdis/jiae161.
Impacto: 5.0. Cuartil: Q1
Benítez L., Castro-Barquero S., Crispi F., Youssef L., Crovetto F., Fischer U., Kameri E., Bueno C., Camos M., Menéndez P., Heinäniemi M., Borkhardt A., Gratacós E.. Maternal Lifestyle and Prenatal Risk Factors for Childhood Leukemia: A Review of the Existing Evidence. Fetal Diagnosis and Therapy. 1 August 2024. DOI: 10.1159/000539141.
Impacto: 1.6. Cuartil: Q3
Bousquets-Muñoz P., Molina O., Varela I., Álvarez-Eguiluz Á., Fernández-Mateos J., Gómez A., Sánchez E.G., Balbín M., Ruano D., Ramírez-Orellana M., Puente X.S., Menéndez P., Velasco-Hernandez T.. Backtracking NOM1::ETV6 fusion to neonatal pathogenesis of t(7;12) (q36;p13) infant AML. Leukemia. August 2024. DOI: 10.1038/s41375-024-02293-9.
Impacto: 12.8. Cuartil: Q1
(1er decil)
Safi R., Menéndez P., Pol A.. Lipid droplets provide metabolic flexibility for cancer progression. FEBS Letters. May 2024. DOI: 10.1002/1873-3468.14820.
Impacto: 3.0. Cuartil: Q2
Mensurado S., Condeço C., Sánchez-Martínez D., Shirley S., Coelho R.M.L., Tirado N., Vinyoles M., Blanco-Domínguez R., Barros L., Galvão B., Custódio N., Gomes da Silva M., Menéndez P., Silva-Santos B.. CD155/PVR determines acute myeloid leukemia targeting by Delta One T cells. Blood. 11 April 2024. DOI: 10.1182/blood.2023022992.
Impacto: 21.0. Cuartil: Q1
(1er decil)
Velasco-Hernandez T., Trincado J.L., Vinyoles M., Closa A., Martínez-Moreno A., Gutiérrez-Agüera F., Molina O., Rodríguez-Cortez V.C., Ximeno-Parpal P., Fernández-Fuentes N., Petazzi P., Beneyto-Calabuig S., Velten L., Romecin P., Casquero R., Abollo-Jiménez F., de la Guardia R.D., Lorden P., Bataller A., Lapillonne H., Stam R.W., Vives S., Torrebadell M., Fuster J.L., Bueno C., Sarry J.E., Eyras E., Heyn H., Menéndez P.. Integrative single-cell expression and functional studies unravels a sensitization to cytarabine-based chemotherapy through HIF pathway inhibition in AML leukemia stem cells. HemaSphere. February 2024. DOI: 10.1002/hem3.45.
Impacto: 7.6. Cuartil: Q1
Molina O., Ortega-Sabater C., Thampi N., Fernández-Fuentes N., Guerrero-Murillo M., Martínez-Moreno A., Vinyoles M., Velasco-Hernández T., Bueno C., Trincado J.L., Granada I., Campos D., Giménez C., Boer J.M., den Boer M.L., Calvo G.F., Camós M., Fuster J.L., Velasco P., Ballerini P., Locatelli F., Mullighan C.G., Spierings D.C.J., Foijer F., Pérez-García V.M., Menéndez P.. Chromosomal instability in aneuploid acute lymphoblastic leukemia associates with disease progression. EMBO Molecular Medicine. 16 January 2024. DOI: 10.1038/s44321-023-00006-w.
Impacto: 9.0. Cuartil: Q1
(1er decil)
Izquierdo M., Ruiz-Navarro J., Baldari C.T., Roda-Navarro P.. Editorial: Structure and function of the immunological and redirecting artificial synapses and their clinical implications. Frontiers in Immunology. 2024. DOI: 10.3389/fimmu.2024.1497118.
Impacto: 5.7. Cuartil: Q1
Petazzi P., Gutierrez-Agüera F., Roca-Ho H., Castaño J., Bueno C., Alvarez N., Forrester L.M., Sevilla A., Fidanza A., Menendez P.. Generation of an inducible dCas9-SAM human PSC line for endogenous gene activation. Frontiers in Cell and Developmental Biology. 2024. DOI: 10.3389/fcell.2024.1484955.
Impacto: 4.6. Cuartil: Q1
Díez-Alonso L., Falgas A., Arroyo-Ródenas J., Romencín P.A., Martínez A., Gómez-Rosel M., Blanco B., Jiménez-Reinoso A., Mayado A., Pérez-Pons A., Aguilar-Sopeña Ó., Ramírez-Fernández Á., Segura-Tudela A., Perez-Amill L., Tapia-Galisteo A., Domínguez-Alonso C., Rubio-Pérez L., Jara M., Solé F., Hangiu O., Almagro L., Albitre Á., Penela P., Sanz L., Anguita E., Valeri A., García-Ortiz A., Río P., Juan M., Martínez-López J., Roda-Navarro P., Martín-Antonio B., Orfao A., Menéndez P., Bueno C., Álvarez-Vallina L.. Engineered T cells secreting anti-BCMA T cell engagers control multiple myeloma and promote immune memory in vivo. Science Translational Medicine. 2024. DOI: 10.1126/scitranslmed.adg7962.
Impacto: 15.8. Cuartil: Q1
(1er decil)
Dediego M.L., Portilla Y., Daviu N., López-García D., Villamayor L., Vázquez-Utrilla P., Mulens-Arias V., Pérez-Yagüe S., Nogales A., Ovejero J.G., Gallo-Cordova A., Enjuanes L., Veintemillas-Verdaguer S., Morales M.P., Barber D.F.. Biocompatible Iron Oxide Nanoparticles Display Antiviral Activity Against Two Different Respiratory Viruses in Mice. International Journal of Nanomedicine. 2024. DOI: 10.2147/IJN.S475323.
Impacto: 6.6. Cuartil: Q1
(1er decil)
Zhang Y.W., Velasco-Hernandez T., Mess J., Lalioti M.E., Romero-Mulero M.C., Obier N., Karantzelis N., Rettkowski J., Schönberger K., Karabacz N., Jäcklein K., Morishima T., Trincado J.L., Romecin P., Martinez A., Takizawa H., Shoumariyeh K., Renders S., Zeiser R., Pahl H.L., Béliveau F., Hébert J., Lehnertz B., Sauvageau G., Menendez P., Cabezas-Wallscheid N.. GPRC5C drives branched-chain amino acid metabolism in leukemogenesis. Blood Advances. 26 December 2023. DOI: 10.1182/bloodadvances.2023010460.
Impacto: 7.4. Cuartil: Q1
Mensali N., Köksal H., Joaquina S., Wernhoff P., Casey N.P., Romecin P., Panisello C., Rodriguez R., Vimeux L., Juzeniene A., Myhre M.R., Fåne A., Ramírez C.C., Maggadottir S.M., Duru A.D., Georgoudaki A.M., Grad I., Maturana A.D., Gaudernack G., Kvalheim G., Carcaboso A.M., de Alava E., Donnadieu E., Bruland Ø.S., Menendez P., Inderberg E.M., Wälchli S.. ALPL-1 is a target for chimeric antigen receptor therapy in osteosarcoma. Nature Communications. December 2023. DOI: 10.1038/s41467-023-39097-x.
Impacto: 14.7. Cuartil: Q1
(1er decil)
Mulens-Arias V., Portilla Y., Pérez-Yagüe S., Ferreras-Martín R., Martín M.E., González V.M., Barber D.F.. An electrostatically conjugated-functional MNK1 aptamer reverts the intrinsic antitumor effect of polyethyleneimine-coated iron oxide nanoparticles in vivo in a human triple-negative cancer xenograft. Cancer Nanotechnology. December 2023. DOI: 10.1186/s12645-023-00204-8.
Impacto: 4.5. Cuartil: Q1
Tomás-Daza L., Rovirosa L., López-Martí P., Nieto-Aliseda A., Serra F., Planas-Riverola A., Molina O., McDonald R., Ghevaert C., Cuatrecasas E., Costa D., Camós M., Bueno C., Menéndez P., Valencia A., Javierre B.M.. Low input capture Hi-C (liCHi-C) identifies promoter-enhancer interactions at high-resolution. Nature Communications. December 2023. DOI: 10.1038/s41467-023-35911-8.
Impacto: 14.7. Cuartil: Q1
(1er decil)
Bueno C., Torres-Ruiz R., Velasco-Hernandez T., Molina O., Petazzi P., Martinez A., Rodriguez V., Vinyoles M., Cantilena S., Williams O., Vega-Garcia N., Rodriguez-Perales S., Segovia J.C., Quintana-Bustamante O., Roy A., Meyer C., Marschalek R., Smith A.L., Milne T.A., Fraga M.F., Tejedor J.R., Menéndez P.. A human genome editing–based MLL::AF4 ALL model recapitulates key cellular and molecular leukemogenic features. Blood. 16 November 2023. DOI: 10.1182/blood.2023020858.
Impacto: 21.0. Cuartil: Q1
(1er decil)
de Lope-Planelles A., González-Novo R., Madrazo E., Peralta-Carrero G., Cruz Rodríguez M.P., Zamora-Carreras H., Torrano V., López-Menéndez H., Roda-Navarro P., Monroy F., Redondo-Muñoz J.. Mechanical stress confers nuclear and functional changes in derived leukemia cells from persistent confined migration. Cellular and Molecular Life Sciences. November 2023. DOI: 10.1007/s00018-023-04968-5.
Impacto: 6.2. Cuartil: Q1
Velasco-Hernandez T., Menéndez P.. Long non-coding RNAs emerge as a novel prognostic indicator in pediatric acute myeloid leukemia. Translational Pediatrics. October 2023. DOI: 10.21037/tp-23-351.
Impacto: 1.5. Cuartil: Q2
Marin-Bejar O., Romero-Moya D., Rodriguez-Ubreva J., Distefano M., Lessi F., Aretini P., Liquori A., Castaño J., Kozyra E., Kotmayer L., Bueno C., Cervera J., Rodriguez-Gallego J.C., Nomdedeu J.F., Murillo- Sanjuán L., de Heredia C.D., Pérez-Martinez A., López-Cadenas F., Martínez-Laperche C., Dorado-Herrero N., Marco F.M., Prósper F., Menendez P., Valcárcel D., Ballestar E., Bödör C., Bigas A., Catalá A., Wlodarski M.W., Giorgetti A.. Epigenome profiling reveals aberrant DNA methylation signature in GATA2 deficiency. Haematologica. September 2023. DOI: 10.3324/haematol.2022.282305.
Impacto: 8.2. Cuartil: Q1
Velasco P., Bautista F., Rubio A., Aguilar Y., Rives S., Dapena J.L., Pérez A., Ramirez M., Saiz-Ladera C., Izquierdo E., Escudero A., Camós M., Vega-García N., Ortega M., Hidalgo-Gómez G., Palacio C., Menéndez P., Bueno C., Montero J., Romecín P.A., Zazo S., Alvarez F., Parras J., Ortega-Sabater C., Chulián S., Rosa M., Cirillo D., García E., García J., Manzano-Muñoz A., Minguela A., Fuster J.L.. The relapsed acute lymphoblastic leukemia network (ReALLNet): a multidisciplinary project from the spanish society of pediatric hematology and oncology (SEHOP). Frontiers in Pediatrics. 22 August 2023. DOI: 10.3389/fped.2023.1269560.
Impacto: 2.1. Cuartil: Q2
Portilla Y., Mulens-Arias V., Daviu N., Paradela A., Pérez-Yagüe S., Barber D.F.. Interaction of Iron Oxide Nanoparticles with Macrophages Is Influenced Distinctly by “Self” and “Non-Self” Biological Identities. ACS Applied Materials and Interfaces. 2 August 2023. DOI: 10.1021/acsami.3c05555.
Impacto: 8.3. Cuartil: Q1
Bueno C., Martínez A., Romecin P.A., Zanetti S.R., Tirtakusuma R., Genesca E., Camós M., Ramírez-Orellana M., Anguita E., Ballerini P., Locatelli F., Fuster J.L., Menéndez P.. TIM3, a human acute myeloid leukemia stem cell marker, does not enrich for leukemia-initiating stem cells in B-cell acute lymphoblastic leukemia. Haematologica. August 2023. DOI: 10.3324/haematol.2022.282394.
Impacto: 8.2. Cuartil: Q1
Lahera A., Vela-Martín L., López-Nieva P., Salgado R.N., Rodríguez-Perales S., Torres-Ruiz R., López-Lorenzo J.L., Cornago J., Llamas P., Fernández-Navarro P., Sánchez-Domínguez R., Segovia J.C., Sastre I., Cobos-Fernández M., Menéndez P., Santos J., Fernández-Piqueras J., Villa-Morales M.. Comprehensive characterization of a novel, oncogenic and targetable SEPTIN6::ABL2 fusion in T-ALL. British Journal of Haematology. August 2023. DOI: 10.1111/bjh.18901.
Impacto: 5.1. Cuartil: Q1
Meyer C., Larghero P., Almeida Lopes B., Burmeister T., Gröger D., Sutton R., Venn N.C., Cazzaniga G., Corral Abascal L., Tsaur G., Fechina L., Emerenciano M., Pombo-de-Oliveira M.S., Lund-Aho T., Lundán T., Montonen M., Juvonen V., Zuna J., Trka J., Ballerini P., Lapillonne H., Van der Velden V.H.J., Sonneveld E., Delabesse E., de Matos R.R.C., Silva M.L.M., Bomken S., Katsibardi K., Keernik M., Grardel N., Mason J., Price R., Kim J., Eckert C., Lo Nigro L., Bueno C., Menendez P., zur Stadt U., Gameiro P., Sedék L., Szczepański T., Bidet A., Marcu V., Shichrur K., Izraeli S., Madsen H.O., Schäfer B.W., Kubetzko S., Kim R., Clappier E., Trautmann H., Brüggemann M., Archer P., Hancock J., Alten J., Möricke A., Stanulla M., Lentes J., Bergmann A.K., Strehl S., Köhrer S., Nebral K., Dworzak M.N., Haas O.A., Arfeuille C., Caye-Eude A., Cavé H., Marschalek R.. The KMT2A recombinome of acute leukemias in 2023. Leukemia. May 2023. DOI: 10.1038/s41375-023-01877-1.
Impacto: 12.8. Cuartil: Q1
(1er decil)
Campos-Gonzalez G., Martinez-Picado J., Velasco-Hernandez T., Salgado M.. Opportunities for CAR-T Cell Immunotherapy in HIV Cure. Viruses. March 2023. DOI: 10.3390/v15030789.
Impacto: 3.8. Cuartil: Q2
Gómez-Morón A., Requena S., Roda-Navarro P., Martín-Cófreces N.B.. Activation kinetics of regulatory molecules during immunological synapse in T cells. Methods in Cell Biology. January 2023. DOI: 10.1016/bs.mcb.2022.10.014.
Carrasco-Padilla C., Hernaiz-Esteban A., Álvarez-Vallina L., Aguilar-Sopeña O., Roda-Navarro P.. Bispecific Antibody Format and the Organization of Immunological Synapses in T Cell-Redirecting Strategies for Cancer Immunotherapy. Pharmaceutics. January 2023. DOI: 10.3390/pharmaceutics15010132.
Impacto: 4.9. Cuartil: Q1
Carrasco-Padilla C., Aguilar-Sopeña O., Gómez-Morón A., Alegre-Gómez S., Sánchez-Madrid F., Martín-Cófreces N.B., Roda-Navarro P.. T cell activation and effector function in the human Jurkat T cell model. Methods in Cell Biology. January 2023. DOI: 10.1016/bs.mcb.2022.09.012.
Palomero J., Panisello C., Lozano-Rabella M., Tirtakasuma R., Díaz-Gómez J., Grases D., Pasamar H., Arregui L., Dorca Duch E., Guerra Fernández E., Vivancos A., De Andrea C.E., Melero I., Ponce J., Vidal A., Piulats J.M., Matias-Guiu X., Gros A.. Biomarkers of tumor-reactive CD4 + and CD8 + TILs associate with improved prognosis in endometrial cancer.. Journal for ImmunoTherapy of Cancer. 29 December 2022. DOI: 10.1136/jitc-2022-005443.
Jiménez-Reinoso A., Tirado N., Martinez-Moreno A., Díaz V.M., García-Peydró M., Hangiu O., Díez-Alonso L., Albitre Á., Penela P., Toribio M.L., Menéndez P., Álvarez-Vallina L., Sánchez Martínez D.. Efficient preclinical treatment of cortical T cell acute lymphoblastic leukemia with T lymphocytes secreting anti-CD1a T cell engagers. Journal for ImmunoTherapy of Cancer. 23 December 2022. DOI: 10.1136/jitc-2022-005333.
Bordoy A.E., Saludes V., Panisello Yagüe D., Clarà G., Soler L., Paris de León A., Casañ C., Blanco-Suárez A., Guerrero-Murillo M., Rodríguez-Ponga B., Noguera-Julian M., Català-Moll F., Pey I., Armengol M.P., Casadellà M., Parera M., Pluvinet R., Sumoy L., Clotet B., Giménez M., Martró E., Cardona P.J., Blanco I.. Monitoring SARS-CoV-2 variant transitions using differences in diagnostic cycle threshold values of target genes. Scientific Reports. December 2022. DOI: 10.1038/s41598-022-25719-9.
Impacto: 4.6. Cuartil: Q2
Portilla Y., Fernández-Afonso Y., Pérez-Yagüe S., Mulens-Arias V., Morales M.P., Gutiérrez L., Barber D.F.. Different coatings on magnetic nanoparticles dictate their degradation kinetics in vivo for 15 months after intravenous administration in mice. Journal of Nanobiotechnology. December 2022. DOI: 10.1186/s12951-022-01747-5.
DeDiego M.L., Portilla Y., Daviu N., López-García D., Villamayor L., Mulens-Arias V., Ovejero J.G., Gallo-Cordova Á., Veintemillas-Verdaguer S., Morales M.P., Barber D.F.. Iron oxide and iron oxyhydroxide nanoparticles impair SARS-CoV-2 infection of cultured cells. Journal of Nanobiotechnology. December 2022. DOI: 10.1186/s12951-022-01542-2.
Mulens-Arias V., Nicolás-Boluda A., Carn F., Gazeau F.. Cationic Polyethyleneimine (PEI)–Gold Nanocomposites Modulate Macrophage Activation and Reprogram Mouse Breast Triple-Negative MET-1 Tumor Immunological Microenvironment. Pharmaceutics. October 2022. DOI: 10.3390/pharmaceutics14102234.
Impacto: 5.4. Cuartil: Q1
Martínez D.S., Tirado N., Mensurado S., Martínez-Moreno A., Romecín P., Agüera F.G., Correia D.V., Silva-Santos B., Menéndez P.. Generation and proof-of-concept for allogeneic CD123 CAR-Delta One T (DOT) cells in acute myeloid leukemia. Journal for ImmunoTherapy of Cancer. 26 September 2022. DOI: 10.1136/jitc-2022-005400.
Ramos-Muntada M., Trincado J.L., Blanco J., Bueno C., Rodríguez-Cortez V.C., Bataller A., López-Millán B., Schwab C., Ortega M., Velasco P., Blanco M.L., Nomdedeu J., Ramírez-Orellana M., Minguela A., Fuster J.L., Cuatrecasas E., Camós M., Ballerini P., Escherich G., Boer J., DenBoer M., Hernández-Rivas J.M., Calasanz M.J., Cazzaniga G., Harrison C.J., Menéndez P., Molina O.. Clonal heterogeneity and rates of specific chromosome gains are risk predictors in childhood high-hyperdiploid B-cell acute lymphoblastic leukemia. Molecular Oncology. August 2022. DOI: 10.1002/1878-0261.13276.
Impacto: 6.6. Cuartil: Q1
Higuera M., Vargas-Accarino E., Torrens M., Gregori J., Salcedo M.T., Martínez-Campreciós J., Torres G., Bermúdez-Ramos M., Bilbao I., Guerrero-Murillo M., Serres-Créixams X., Merino X., Rodríguez-Frías F., Quer J., Mínguez B.. Ultra Deep Sequencing of Circulating Cell-Free DNA as a Potential Tool for Hepatocellular Carcinoma Management. Cancers. August 2022. DOI: 10.3390/cancers14163875.
Impacto: 5.2. Cuartil: Q2
Bueno C., Barrera S., Bataller A., Ortiz-Maldonado V., Elliot N., O'Byrne S., Wang G., Rovira M., Gutierrez-Agüera F., Trincado J.L., González-González M., Morgades M., Sorigué M., Bárcena P., Zanetti S.R., Torrebadell M., Vega-Garcia N., Rives S., Mallo M., Sole F., Mead A.J., Roberts I., Thongjuea S., Psaila B., Juan M., Delgado J., Urbano-Ispizúa A., Ribera J.M., Orfao A., Roy A., Menendez P.. CD34<sup>+</sup>CD19<sup>−</sup>CD22<sup>+</sup> B-cell progenitors may underlie phenotypic escape in patients treated with CD19-directed therapies. Blood. 7 July 2022. DOI: 10.1182/blood.2021014840.
Impacto: 20.3. Cuartil: Q1
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Zhang Y.W., Mess J., Aizarani N., Mishra P., Johnson C., Romero-Mulero M.C., Rettkowski J., Schönberger K., Obier N., Jäcklein K., Woessner N.M., Lalioti M.E., Velasco-Hernandez T., Sikora K., Wäsch R., Lehnertz B., Sauvageau G., Manke T., Menendez P., Walter S.G., Minguet S., Laurenti E., Günther S., Grün D., Cabezas-Wallscheid N.. Hyaluronic acid–GPRC5C signalling promotes dormancy in haematopoietic stem cells. Nature Cell Biology. July 2022. DOI: 10.1038/s41556-022-00931-x.
Impacto: 21.3. Cuartil: Q1
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Wang-Wang J.H., Bordoy A.E., Martró E., Quesada M.D., Pérez-Vázquez M., Guerrero-Murillo M., Tiburcio A., Navarro M., Castellà L., Sopena N., Casas I., Saludes V., Giménez M., Cardona P.J.. Evaluation of Fourier Transform Infrared Spectroscopy as a First-Line Typing Tool for the Identification of Extended-Spectrum β-Lactamase-Producing Klebsiella pneumoniae Outbreaks in the Hospital Setting. Frontiers in Microbiology. 9 June 2022. DOI: 10.3389/fmicb.2022.897161.
Impacto: 5.2. Cuartil: Q2
García-Cuesta E.M., Rodríguez-Frade J.M., Gardeta S.R., D’Agostino G., Martínez P., Palacios B.S., Cascio G., Wolf T., Mateos N., Ayala-Bueno R., Santiago C.A., Lucas P., Llorente L., Allende L.M., González-Granado L.I., Martín-Cófreces N., Roda-Navarro P., Sallusto F., Sánchez-Madrid F., García-Parajo M.F., Martínez-Muñoz L., Mellado M.. Altered CXCR4 dynamics at the cell membrane impairs directed cell migration in WHIM syndrome patients. Proceedings of the National Academy of Sciences of the United States of America. 24 May 2022. DOI: 10.1073/pnas.2119483119.
Impacto: 11.1. Cuartil: Q1
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Carrasco-Padilla C., Roda-Navarro P.. CRISPR/Cas9-mediated genome editing assists protein dynamics studies in live cells. European Journal of Cell Biology. April 2022. DOI: 10.1016/j.ejcb.2022.151203.
Impacto: 6.6. Cuartil: Q2
Zamora-Perez P., Xiao C., Sanles-Sobrido M., Rovira-Esteva M., Conesa J.J., Mulens-Arias V., Jaque D., Rivera-Gil P.. Multiphoton imaging of melanoma 3D models with plasmonic nanocapsules. Acta Biomaterialia. 1 April 2022. DOI: 10.1016/j.actbio.2022.01.052.
Impacto: 9.7. Cuartil: Q1
(1er decil)
Blanco B., Ramírez-Fernández Á., Bueno C., Argemí-Muntadas L., Fuentes P., Aguilar-Sopeña Ó., Gutierrez-Agüera F., Zanetti S.R., Tapia-Galisteo A., Díez-Alonso L., Segura-Tudela A., Castellá M., Marzal B., Betriu S., Harwood S.L., Compte M., Lykkemark S., Erce-Llamazares A., Rubio-Pérez L., Jiménez-Reinoso A., Domínguez-Alonso C., Neves M., Morales P., Paz-Artal E., Guedan S., Sanz L., Toribio M.L., Roda-Navarro P., Juan M., Menéndez P., Álvarez-Vallina L.. Overcoming CAR-Mediated CD19 Downmodulation and Leukemia Relapse with T Lymphocytes Secreting Anti-CD19 T-cell Engagers. Cancer Immunology Research. April 2022. DOI: 10.1158/2326-6066.CIR-21-0853.
Impacto: 10.1. Cuartil: Q1
Yuan O., Ugale A., de Marchi T., Anthonydhason V., Konturek-Ciesla A., Wan H., Eldeeb M., Drabe C., Jassinskaja M., Hansson J., Hidalgo I., Velasco-Hernandez T., Cammenga J., Magee J.A., Niméus E., Bryder D.. A somatic mutation in moesin drives progression into acute myeloid leukemia. Science Advances. April 2022. DOI: 10.1126/sciadv.abm9987.
Impacto: 13.6. Cuartil: Q1
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Lopez-Millan B., Costales P., Gutiérrez-Agüera F., de la Guardia R.D., Roca-Ho H., Vinyoles M., Rubio-Gayarre A., Safi R., Castaño J., Romecín P.A., Ramírez-Orellana M., Anguita E., Jeremias I., Zamora L., Rodríguez-Manzaneque J.C., Bueno C., Morís F., Menendez P.. The Multi-Kinase Inhibitor EC-70124 Is a Promising Candidate for the Treatment of FLT3-ITD-Positive Acute Myeloid Leukemia. Cancers. March-2 2022. DOI: 10.3390/cancers14061593.
Impacto: 5.2. Cuartil: Q2
Zanetti S.R., Velasco-Hernandez T., Gutierrez-Agüera F., Díaz V.M., Romecín P.A., Roca-Ho H., Sánchez-Martínez D., Tirado N., Baroni M.L., Petazzi P., Torres-Ruiz R., Molina O., Bataller A., Fuster J.L., Ballerini P., Juan M., Jeremias I., Bueno C., Menéndez P.. A novel and efficient tandem CD19- and CD22-directed CAR for B cell ALL. Molecular Therapy. 2 February 2022. DOI: 10.1016/j.ymthe.2021.08.033.
Impacto: 12.4. Cuartil: Q1
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Portilla Y., Mulens-Arias V., Paradela A., Ramos-Fernández A., Pérez-Yagüe S., Morales M.P., Barber D.F.. The surface coating of iron oxide nanoparticles drives their intracellular trafficking and degradation in endolysosomes differently depending on the cell type. Biomaterials. February 2022. DOI: 10.1016/j.biomaterials.2022.121365.
Impacto: 14.0. Cuartil: Q1
(1er decil)
Rodriguez-Cortez V.C., Navarrete-Meneses M.P., Molina O., Velasco-Hernandez T., Gonzalez J., Romecin P., Gutierrez-Aguera F., Roca-Ho H., Vinyoles M., Kowarz E., Marin P., Rodriguez-Perales S., Gomez-Marin C., Perez-Vera P., Cortes-Ledesma F., Bigas A., Terron A., Bueno C., Menendez P.. The insecticides permethrin and chlorpyrifos show limited genotoxicity and no leukemogenic potential in human and murine hematopoietic stem progenitor cells. Haematologica. February 2022. DOI: 10.3324/haematol.2021.279047.
Impacto: 10.1. Cuartil: Q1
(1er decil)
Galindo-Campos M.A., Lutfi N., Bonnin S., Martínez C., Velasco-Hernandez T., García-Hernández V., Martín-Caballero J., Ampurdanés C., Gimeno R., Colomo L., Roué G., Guilbaud G., Dantzer F., Navarro P., Murga M., Fernández-Capetillo O., Bigas A., Menéndez P., Sale J.E., Yélamos J.. Distinct roles for PARP-1 and PARP-2 in c-Myc–driven B-cell lymphoma in mice. Blood. 13 January 2022. DOI: 10.1182/blood.2021012805.
Impacto: 20.3. Cuartil: Q1
(1er decil)
Romecín P.A., Vinyoles M., López-Millán B., De La Guardia R.D., Atucha N.M., Querol S., Bueno C., Benitez R., Gonzalez-Rey E., Delgado M., Menéndez P.. Robust in Vitro and in Vivo Immunosuppressive and Anti-inflammatory Properties of Inducible Caspase-9-mediated Apoptotic Mesenchymal Stromal/Stem Cell. Stem Cells Translational Medicine. January 2022. DOI: 10.1093/stcltm/szab007.
Impacto: 6.0. Cuartil: Q1
Ramírez-Fernández Á., Aguilar-Sopeña Ó., Díez-Alonso L., Segura-Tudela A., Domínguez-Alonso C., Roda-Navarro P., Álvarez-Vallina L., Blanco B.. Synapse topology and downmodulation events determine the functional outcome of anti-CD19 T cell-redirecting strategies. OncoImmunology. 2022. DOI: 10.1080/2162402X.2022.2054106.
Impacto: 7.2. Cuartil: Q1
Petazzi P., Menéndez P., Sevilla A.. CRISPR/Cas9–Mediated Gene Knockout and Knockin Human iPSCs. Methods in Molecular Biology. 2022. DOI: 10.1007/7651_2020_337.
Tapia-Galisteo A., Sánchez Rodríguez Í., Aguilar-Sopeña O., Harwood S.L., Narbona J., Ferreras Gutierrez M., Navarro R., Martín-García L., Corbacho C., Compte M., Lacadena J., Blanco F.J., Chames P., Roda-Navarro P., Álvarez-Vallina L., Sanz L.. Trispecific T-cell engagers for dual tumor-targeting of colorectal cancer. OncoImmunology. 2022. DOI: 10.1080/2162402X.2022.2034355.
Impacto: 7.2. Cuartil: Q1
Molina O., Bataller A., Thampi N., Ribera J., Granada I., Velasco P., Fuster J.L., Menéndez P.. Near-haploidy and low-hypodiploidy in b-cell acute lymphoblastic leukemia: When less is too much. Cancers. January-1 2022. DOI: 10.3390/cancers14010032.
Impacto: 5.2. Cuartil: Q2
Garcia B., Catasus N., Ros A., Rosas I., Negro A., Guerrero-Murillo M., Valero A.M., Duat-Rodriguez A., Becerra J.L., Bonache S., Garcia C.L., Comas C., Bielsa I., Serra E., Hernández-Chico C., Martin Y., Castellanos E., Blanco I.. Neurofibromatosis type 1 families with first-degree relatives harbouring distinct NF1 pathogenic variants. Genetic counselling and familial diagnosis: what should be offered?. Journal of Medical Genetics. 2022. DOI: 10.1136/jmedgenet-2021-108301.
Impacto: 4.0. Cuartil: Q2
Goterris L., Pasic L., Guerrero Murillo M., Kan A., Anton A., Aguilar Company J., Ruiz-Camps I., Meyer W., Martin-Gomez M.T.. Pneumocystis jirovecii genetic diversity in a Spanish tertiary hospital. Medical Mycology. 1 January 2022. DOI: 10.1093/mmy/myab065.
Impacto: 2.9. Cuartil: Q1
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Jaffredo T., Balduini A., Bigas A., Bernardi R., Bonnet D., Canque B., Charbord P., Cumano A., Delwel R., Durand C., Fibbe W., Forrester L., De Franceschi L., Ghevaert C., Gjertsen B., Gottgens B., Graf T., Heidenreich O., Hermine O., Higgs D., Kleanthous M., Klump H., Kouskoff V., Krause D., Lacaud G., Lo Celso C., Martens J.H.A., Méndez-Ferrer S., Menendez P., Oostendorp R., Philipsen S., Porse B., Raaijmakers M., Robin C., Stunnenberg H., Theilgaard-Mönch K., Touw I., Vainchenker W., Corrons J.L.V., Yvernogeau L., Schuringa J.J.. The eha research roadmap: normal hematopoiesis. HemaSphere. 30 December 2021. DOI: 10.1097/HS9.0000000000000669.
Impacto: 8.3. Cuartil: Q1
Bataller A., Guijarro F., Caye-Eude A., Strullu M., Sterin A., Molina O., Chevallier P., Zaliova M., Zuna J., Mozas P., Magnano L., Grardel N., Cornillet-Lefebvre P., Fu J.F., Shih L.Y., Boneva T., Nacheva E., Bea S., Lopez-Guerra M., Bueno C., Menendez P., Esteve J., Larghero P., Meyer C., Marschalek R.. KMT2A-CBL rearrangements in acute leukemias: clinical characteristics and genetic breakpoints. Blood Advances. 28 December 2021. DOI: 10.1182/bloodadvances.2021005736.
Impacto: 7.637. Cuartil: Q1
De La Guardia R.D., Velasco-Hernandez T., Gutiérrez-Agüera F., Roca-Ho H., Molina O., Nombela-Arrieta C., Bataller A., Fuster J.L., Anguita E., Vives S., Zamora L., Nomdedeu J., Gómez-Casares M.T., Ramírez-Orellana M., Lapillonne H., Ramos-Mejia V., Rodríguez-Manzaneque J.C., Bueno C., Lopez-Millan B., Menéndez P.. Engraftment characterization of risk-stratified AML in NSGS mice. Blood Advances. 14 December 2021. DOI: 10.1182/bloodadvances.2020003958.
Impacto: 7.637. Cuartil: Q1
Cortese M.F., González C., Gregori J., Casillas R., Carioti L., Guerrero-Murillo M., Riveiro-Barciela M., Godoy C., Sopena S., Yll M., Quer J., Rando A., Lopez-Martinez R., Pacín Ruiz B., García-García S., Esteban-Mur R., Tabernero D., Buti M., Rodríguez-Frías F.. Sophisticated viral quasispecies with a genotype-related pattern of mutations in the hepatitis B X gene of HBeAg-ve chronically infected patients. Scientific Reports. December 2021. DOI: 10.1038/s41598-021-83762-4.
Impacto: 4.996. Cuartil: Q2
Ribeiro M.L., Reyes-Garau D., Vinyoles M., Pelejà N.P., Santos J.C., Armengol M., Fernández-Serrano M., Mor A.S., Bech-Serra J.J., Blecua P., Musulen E., de la Torre C., Miskin H., Esteller M., Bosch F., Menéndez P., Normant E., Roué G.. Antitumor activity of the novel BTK inhibitor TG-1701 is associated with disruption of ikaros signaling in patients with B-cell non–hodgkin lymphoma. Clinical Cancer Research. 1 December 2021. DOI: 10.1158/1078-0432.CCR-21-1067.
Impacto: 13.801. Cuartil: Q1
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Martin-Cofreces N.B., Sanchez-Madrid F., Roda-Navarro P.. Editorial: Cytoskeleton Dynamics as Master Regulator of Organelle Reorganization and Intracellular Signaling for Cell-Cell Competition. Frontiers in Cell and Developmental Biology. 28 October 2021. DOI: 10.3389/fcell.2021.782559.
Impacto: 6.081. Cuartil: Q1
Manzano-Muñoz A., Alcon C., Menéndez P., Ramírez M., Seyfried F., Debatin K.M., Meyer L.H., Samitier J., Montero J.. MCL-1 Inhibition Overcomes Anti-apoptotic Adaptation to Targeted Therapies in B-Cell Precursor Acute Lymphoblastic Leukemia. Frontiers in Cell and Developmental Biology. 9 September 2021. DOI: 10.3389/fcell.2021.695225.
Impacto: 6.081. Cuartil: Q1
García-Castillo J., Alcaraz-Pérez F., Martínez-Balsalobre E., García-Moreno D., Rossmann M.P., Fernández-Lajarín M., Bernabé-García M., Pérez-Oliva A.B., Rodríguez-Cortez V.C., Bueno C., Adatto I., Agarwal S., Menéndez P., Zon L.I., Mulero V., Cayuela M.L.. Telomerase RNA recruits RNA polymerase II to target gene promoters to enhance myelopoiesis. Proceedings of the National Academy of Sciences of the United States of America. 10 August 2021. DOI: 10.1073/pnas.2015528118.
Impacto: 12.779. Cuartil: Q1
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Tejedor J.R., Bueno C., Vinyoles M., Petazzi P., Agraz-Doblas A., Cobo I., Torres-Ruiz R., Bayón G.F., Pérez R.F., López-Tamargo S., Gutierrez-Agüera F., Santamarina-Ojeda P., Ramírez-Orellana M., Bardini M., Cazzaniga G., Ballerini P., Schneider P., Stam R.W., Varela I., Fraga M.F., Fernández A.F., Menéndez P.. Integrative methylome-transcriptome analysis unravels cancer cell vulnerabilities in infant MLLrearranged B cell acute lymphoblastic leukemia. Journal of Clinical Investigation. July 2021. DOI: 10.1172/JCI138833.
Impacto: 19.456. Cuartil: Q1
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de Barrios O., Galaras A., Trincado J.L., Azagra A., Collazo O., Meler A., Agraz-Doblas A., Bueno C., Ballerini P., Cazzaniga G., Stam R.W., Varela I., De Lorenzo P., Valsecchi M.G., Hatzis P., Menéndez P., Parra M.. HDAC7 is a major contributor in the pathogenesis of infant t(4;11) proB acute lymphoblastic leukemia. Leukemia. July 2021. DOI: 10.1038/s41375-020-01097-x.
Impacto: 12.883. Cuartil: Q1
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Llorens-Revull M., Costafreda M.I., Rico A., Guerrero-Murillo M., Soria M.E., Píriz-Ruzo S., Vargas-Accarino E., Gabriel-Medina P., Rodríguez-Frías F., Riveiro-Barciela M., Perales C., Quer J., Sauleda S., Esteban J.I., Bes M.. Partial restoration of immune response in Hepatitis C patients after viral clearance by direct-acting antiviral therapy. PLoS ONE. July 2021. DOI: 10.1371/journal.pone.0254243.
Impacto: 3.752. Cuartil: Q2
Mulens-Arias V., Rojas J.M., Barber D.F.. The Use of Iron Oxide Nanoparticles to Reprogram Macrophage Responses and the Immunological Tumor Microenvironment. Frontiers in Immunology. 9 June 2021. DOI: 10.3389/fimmu.2021.693709.
Impacto: 8.786. Cuartil: Q1
Gutierrez-Agüera F., Rodriguez-Cortez V., Petazzi P., Bueno C., Menendez P.. A Benchmark Side-by-Side Comparison of Two Well-Established Protocols for in vitro Hematopoietic Differentiation From Human Pluripotent Stem Cells. Frontiers in Cell and Developmental Biology. 21 May 2021. DOI: 10.3389/fcell.2021.636704.
Impacto: 6.081. Cuartil: Q1
Gazeau F., Mulens-Arias V., Nicolás-Boluda A., Pinto A., Balfourier A., Carn F., Silva A.K.A., Pocard M.. Tumor-selective immune-active mild hyperthermia associated with chemotherapy in colon peritoneal metastasis by photoactivation of fluorouracil-gold nanoparticle complexes. ACS Nano. 23 February 2021. DOI: 10.1021/acsnano.0c10276.
Impacto: 18.027. Cuartil: Q1
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Molina O., Abad M.A., Solé F., Menéndez P.. Aneuploidy in Cancer: Lessons from Acute Lymphoblastic Leukemia. Trends in Cancer. January 2021. DOI: 10.1016/j.trecan.2020.08.008.
Impacto: 19.161. Cuartil: Q1
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Godfrey L., Crump N.T., O’Byrne S., Lau I.J., Rice S., Harman J.R., Jackson T., Elliott N., Buck G., Connor C., Thorne R., Knapp D.J.H.F., Heidenreich O., Vyas P., Menendez P., Inglott S., Ancliff P., Geng H., Roberts I., Roy A., Milne T.A.. H3K79me2/3 controls enhancer–promoter interactions and activation of the pan-cancer stem cell marker PROM1/CD133 in MLL-AF4 leukemia cells. Leukemia. January 2021. DOI: 10.1038/s41375-020-0808-y.
Impacto: 12.883. Cuartil: Q1
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Petazzi P., Menendez P.. A NEWral approach for HSC production in vitro?. Blood. 17 December 2020. DOI: 10.1182/blood.2020007864.
Impacto: 22.113. Cuartil: Q1
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Castro-Sánchez P., Hernández-Pérez S., Aguilar-Sopeña O., Ramírez-Muñoz R., Rodríguez-Perales S., Torres-Ruiz R., Roda-Navarro P.. Fast Diffusion Sustains Plasma Membrane Accumulation of Phosphatase of Regenerating Liver-1. Frontiers in Cell and Developmental Biology. 4 December 2020. DOI: 10.3389/fcell.2020.585842.
Impacto: 6.684. Cuartil: Q1
Martinez-Lage M., Torres-Ruiz R., Puig-Serra P., Moreno-Gaona P., Martin M.C., Moya F.J., Quintana-Bustamante O., Garcia-Silva S., Carcaboso A.M., Petazzi P., Bueno C., Mora J., Peinado H., Segovia J.C., Menendez P., Rodriguez-Perales S.. In vivo CRISPR/Cas9 targeting of fusion oncogenes for selective elimination of cancer cells. Nature Communications. 1 December 2020. DOI: 10.1038/s41467-020-18875-x.
Impacto: 14.919. Cuartil: Q1
(1er decil)
Pasic L., Goterris L., Guerrero-Murillo M., Irinyi L., Kan A., Ponce C.A., Vargas S.L., Martin-Gomez M.T., Meyer W.. Consensus multilocus sequence typing scheme for pneumocystis jirovecii. Journal of Fungi. December 2020. DOI: 10.3390/jof6040259.
Impacto: 5.816. Cuartil: Q1
Mulens-Arias V., Balfourier A., Nicolás-Boluda A., Carn F., Gazeau F.. Endocytosis-driven gold nanoparticle fractal rearrangement in cells and its influence on photothermal conversion. Nanoscale. 14 November 2020. DOI: 10.1039/d0nr05886f.
Impacto: 7.79. Cuartil: Q1
Zanetti S.R., Romecin P.A., Vinyoles M., Juan M., Fuster J.L., Cámos M., Querol S., Delgado M., Menendez P.. Bone marrow MSC from pediatric patients with B-ALL highly immunosuppress T-cell responses but do not compromise CD19-CAR T-cell activity. Journal for ImmunoTherapy of Cancer. 31 August 2020. DOI: 10.1136/jitc-2020-001419.
Impacto: 13.751. Cuartil: Q1
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Bueno C., Ballerini P., Varela I., Menendez P., Bashford-Rogers R.. Shared D-J rearrangements reveal cell of origin of TCF3-ZNF384 and PTPN11 mutations in monozygotic twins with concordant BCP-ALL. Blood. 27 August 2020. DOI: 10.1182/blood.2020006604.
Impacto: 22.113. Cuartil: Q1
(1er decil)
Velasco-Hernandez T., Zanetti S.R., Roca-Ho H., Gutierrez-Aguera F., Petazzi P., Sánchez-Martínez D., Molina O., Baroni M.L., Fuster J.L., Ballerini P., Bueno C., Fernandez-Fuentes N., Engel P., Menendez P.. Efficient elimination of primary B-ALL cells in vitro and in vivo using a novel 4-1BB-based CAR targeting a membrane-distal CD22 epitope. Journal for ImmunoTherapy of Cancer. 11 August 2020. DOI: 10.1136/jitc-2020-000896.
Impacto: 13.751. Cuartil: Q1
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Molina O., Vinyoles M., Granada I., Roca-Ho H., Gutierrez-Agüera F., Valledor L., López-López C.M., Rodríguez-González P., Trincado J.L., Menéndez S.T., Pal D., Ballerini P., den Boer M.L., Plensa I., Mar Perez-Iribarne M., Rodríguez-Perales S., Calasanz M.J., Ramírez-Orellana M., Rodríguez R., Camós M., Calvo M., Bueno C., Menéndez P.. Impaired condensin complex and Aurora B kinase underlie mitotic and chromosomal defects in hyperdiploid B-cell ALL. Blood. 16 July 2020. DOI: 10.1182/blood.2019002538.
Impacto: 22.113. Cuartil: Q1
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Beneforti L., Dander E., Bresolin S., Bueno C., Acunzo D., Bertagna M., Ford A., Gentner B., Kronnie G.t., Vergani P., Menéndez P., Biondi A., D’Amico G., Palmi C., Cazzaniga G.. Pro-inflammatory cytokines favor the emergence of ETV6-RUNX1-positive pre-leukemic cells in a model of mesenchymal niche. British Journal of Haematology. 1 July 2020. DOI: 10.1111/bjh.16523.
Impacto: 6.998. Cuartil: Q1
Mirones I., Moreno L., Patiño-García A., Lizeaga G., Moraleda J.M., Toribio M.L., Pérez-Martínez A., Sisinni L., García-Morín M., Anguita J., Ramírez M., Díaz M.Á., González M., Alonso L., Rives S., Alonso M.M., Palomo P., Verdú-Amorós J., Martínez I., Guerra-García P., Fuster J.L., Sánchez-Salinas A., Blanquer M., García-Castro J., van Santen H.M., Menéndez P.. Immunotherapy with CAR-T cells in paediatric haematology-oncology. Anales de Pediatria. July 2020. DOI: 10.1016/j.anpedi.2019.12.014.
Impacto: 1.5. Cuartil: Q4
Baroni M.L., Martinez D.S., Aguera F.G., Ho H.R., Castella M., Zanetti S.R., Hernandez T.V., de la Guardia R.D., Castaño J., Anguita E., Vives S., Nomdedeu J., Lapillone H., Bras A.E., van der Velden V.H.J., Junca J., Marin P., Bataller A., Esteve J., Vick B., Jeremias I., Lopez A., Sorigue M., Bueno C., Menendez P.. 41BB-based and CD28-based CD123-redirected T-cells ablate human normal hematopoiesis in vivo. Journal for ImmunoTherapy of Cancer. 10 June 2020. DOI: 10.1136/jitc-2020-000845.
Impacto: 13.751. Cuartil: Q1
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Petazzi P., Torres-Ruiz R., Fidanza A., Roca-Ho H., Gutierrez-Agüera F., Castaño J., Rodriguez-Perales S., Díaz de la Guardia R., López-Millán B., Bigas A., Forrester L.M., Bueno C., Menéndez P.. Robustness of Catalytically Dead Cas9 Activators in Human Pluripotent and Mesenchymal Stem Cells. Molecular Therapy Nucleic Acids. 5 June 2020. DOI: 10.1016/j.omtn.2020.02.009.
Impacto: 8.886. Cuartil: Q1
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Yll M., Cortese M.F., Guerrero-Murillo M., Orriols G., Gregori J., Casillas R., González C., Sopena S., Godoy C., Vila M., Tabernero D., Quer J., Rando A., Lopez-Martinez R., Esteban R., Riveiro-Barciela M., Buti M., Rodríguez-Friás F.. Conservation and variability of hepatitis B core at different chronic hepatitis stages. World Journal of Gastroenterology. 28 May 2020. DOI: 10.3748/WJG.V26.I20.2584.
Impacto: 5.742. Cuartil: Q2
Mulens-Arias V., Rojas J.M., Barber D.F.. The intrinsic biological identities of iron oxide nanoparticles and their coatings: Unexplored territory for combinatorial therapies. Nanomaterials. May 2020. DOI: 10.3390/nano10050837.
Impacto: 5.076. Cuartil: Q1
Balfourier A., Mulens-Arias V., Gazeau F., Carn F.. Rational Design of Fractal Gold Nanosphere Assemblies with Optimized Photothermal Conversion Using a Quantitative Structure Property Relationship (QSPR) Approach. Journal of Physical Chemistry C. 23 April 2020. DOI: 10.1021/acs.jpcc.0c00384.
Impacto: 4.126. Cuartil: Q2
Aguilar-Sopeña O., Hernández-Pérez S., Alegre-Gómez S., Castro-Sánchez P., Iglesias-Ceacero A., Lazo J.S., Roda-Navarro P.. Effect of pharmacological inhibition of the catalytic activity of phosphatases of regenerating liver in early t cell receptor signaling dynamics and IL-2 production. International Journal of Molecular Sciences. 1 April 2020. DOI: 10.3390/ijms21072530.
Impacto: 5.923. Cuartil: Q1