RED TERAV - Investigadores

Investigadores

Clínica Universidad de Navarra (UNAV). Pamplona.

Terapia Génica

Inmunoterapia Celular (células CAR)

Terapia de células somáticas y medicina regenerativa

Desarrollos Tecnológicos y Terapéuticos

Investigadores
Publicaciones

Felipe Prosper Cardoso

Investigador principal

Grupo de Investigación: Clínica Universidad de Navarra (UNAV). Pamplona.

EMMA MUIÑOS LOPEZ

Investigador colaborador

Grupo de Investigación: Clínica Universidad de Navarra (UNAV). Pamplona.

Froilán Granero Moltó

Investigador colaborador

Grupo de Investigación: Clínica Universidad de Navarra (UNAV). Pamplona.

Juan José Lasarte Sagastibelza

Investigador colaborador

Grupo de Investigación: Clínica Universidad de Navarra (UNAV). Pamplona.

JUAN ROBERTO RODRIGUEZ MADOZ

Investigador colaborador

Grupo de Investigación: Clínica Universidad de Navarra (UNAV). Pamplona.

Susana Inogés Sancho

Investigador colaborador

Grupo de Investigación: Clínica Universidad de Navarra (UNAV). Pamplona.

Oyon D., Lopez-Pascual A., Castello-Uribe B., Uriarte I., Orsi G., Llorente S., Elurbide J., Adan-Villaescusa E., Valbuena-Goiricelaya E., Irigaray-Miramon A., Latasa M.U., Martinez-Perez L.A., Bonetti L.R., Prosper F., Ponz-Sarvise M., Vicent S., Pineda-Lucena A., Ruiz-Clavijo D., Sangro B., Larracoechea U.A., Tian T.V., Casadei-Gardini A., Amat I., Arechederra M., Berasain C., Urman J.M., Avila M.A., Fernandez-Barrena M.G.. Targeting of the G9a, DNMT1 and UHRF1 epigenetic complex as an effective strategy against pancreatic ductal adenocarcinoma. Journal of Experimental and Clinical Cancer Research. December 2025. DOI: 10.1186/s13046-024-03268-5.

Impacto: 11.4. Cuartil: Q1 (1er decil)

Bernasconi-Bisio F., Molina E., Ibarra V., Ibáñez-Sala I., Rochira F., Jauregui P., Rodríguez-Diaz S., Martínez-Turrillas R., Azagra-Barber I., Gómez-Cebrián N., Lasarte J.J., Puchades-Carrasco L., Vanrell L., Rodríguez-Madoz J.R., Prósper F., Pineda-Lucena A.. Discovery and preclinical development of a SdAb-based CAR-T technology for targeting CD33 in AML. Molecular Therapy Oncology. 20 March 2025. DOI: 10.1016/j.omton.2025.200949.

Diez B., Calviño C., Fernández-García M., Rodríguez-Márquez P., Rodríguez-Díaz S., Martínez-Turillas R., Ceballos C., Illarramendi J., Serrano-López J., Miskey C., Navarro-Bailón A., López-Corral L., Llamas P., Redondo M., Sánchez-Guijo F., Rifon J., Alfonso-Piérola A., Ivics Z., Inogés S., López-Díaz de Cerio A., Yanez R., Bueren J.A., Rodríguez-Madoz J.R., Prosper F.. Generation and GMP scale-up of human CAR-T cells using non-viral Sleeping Beauty transposons for B cell malignances. Molecular Therapy Methods and Clinical Development. 13 March 2025. DOI: 10.1016/j.omtm.2025.101425.

Peña-Gutiérrez I., Olalla-Sastre B., Río P., Rodríguez-Madoz J.R.. Beyond precision: evaluation of off-target clustered regularly interspaced short palindromic repeats/Cas9–mediated genome editing. Cytotherapy. March 2025. DOI: 10.1016/j.jcyt.2024.10.010.

Impacto: 3.7. Cuartil: Q1

Gómez-Echarte N., José-Enériz E.S., Carrasco-León A., Barrena N., Miranda E., Garate L., García-Torre B., Alonso-Moreno S., Gimenez-Camino N., Urizar-Compains E., Olaverri-Mendizabal D., Aguirre-Ruiz P., Ariceta B., Tamariz-Amador L.E., Rodriguez-Otero P., Planes F.J., Belver L., Martín-Subero J.I., Prosper F., Agirre X.. BET inhibitors downregulate the expression of the essential lncRNA SMILO in multiple myeloma through regulation of the transcription factor FLI1. Haematologica. February 2025. DOI: 10.3324/haematol.2024.285966.

Impacto: 8.2. Cuartil: Q1

Lamo-Espinosa J.M., Suárez-López del Amo Á., Núñez-Córdoba J.M., Blanco J.F., Sánchez M., Moreno V., Cabrera M., Granero-Moltó F., Muiños E., Mazo M.M., Crespo-Cullell Í., Mora G., Delgado D., Pompei-Fernández O., Aquerreta J.D., Sola M.V., Valentí-Azcárate A., Andreu E.J., López-Parra M., Villarón E.M., Valentí-Nin J.R., Sánchez-Guijo F., Prósper F.. Effect of Hyaluronic Acid Compared to Platelet-Rich Plasma as Adjuvants to Bone Marrow Mesenchymal Stem Cell Treatment of Knee Osteoarthritis: Analysis from Two Clinical Trials. Diagnostics. February 2025. DOI: 10.3390/diagnostics15030309.

Impacto: 3.0. Cuartil: Q1

Lasa M., Notarfranchi L., Agullo C., Gonzalez C., Castro S., Perez J.J., Burgos L., Guerrero C., Calasanz M.J., Flores-Montero J., Oriol A., Bargay J., Rios R., Cabañas V., Cabrera C., Martinez-Martinez R., Encinas C., De Arriba F., Hernandez M.T., Palomera L., Orfao A., Martinez-Lopez J., Mateos M.V., San-Miguel J., Lahuerta J.J., Rosiñol L., Blade J., Cedena M.T., Puig N., Paiva B., Casanova M., Couto C., Carrillo E., González E., González A.P., Sampol A., Suárez A., Montes C., Calle M.D.C., Casado L.F., De Miguel D., Ibáñez Á., Labrador J., García A., Escalante F., Aguilar C., Escoda L., Sureda A.M., Motlló C., González Y., Monreal E., Soler J.A., Granell M., Cabezudo E., Mª Martí J., García A., Gironella M., Dios A., Méndez J.Á., González M.S., Nájera M.J., Peñalver F.J., Bravo P., Hernández J.Á., De Oteyza J.P., Del Barrio R.I., De La Guía A.L., Alegre A., Krsnik I., Ruíz E., Blanchard M.J., Íñigo B., Giménez E., Riaza R., Prieto E., Romera M., Mª Moraleda J., Prósper F., Mª Arguiñano J., Puente M., Gutiérrez X., Teruel A.I., Rivas P., Jarque I., Fernández Á., Santamaría A., Martínez C.. Minimally Invasive Assessment of Peripheral Residual Disease during Maintenance or Observation in Transplant-Eligible Patients with Multiple Myeloma. Journal of Clinical Oncology. 10 January 2025. DOI: 10.1200/JCO.24.00635.

Impacto: 42.1. Cuartil: Q1 (1er decil)

Eckmann J., Fauti T., Biehl M., Zabaleta A., Blanco L., Lelios I., Gottwald S., Rae R., Lechner S., Bayer C., Dekempe Q., Osl F., Carrié N., Kassem S., Lorenz S., Christopeit T., Carpy A., Bujotzek A., Bröske A.M., Dekhtiarenko I., Attig J., Kunz L., Cremasco F., Adelfio R., Fertig G., Dengl S., Gassner C., Bormann F., Kirstenpfad C., Kraft T., Diggelmann S., Knobloch M., Hage C., Feddersen R., Heidkamp G., Pöschinger T., Mayoux M., Bernasconi L., Prosper F., Dumontet C., Martinet L., Leclair S., Xu W., Paiva B., Klein C., Umaña P.. Forimtamig, a novel GPRC5D-targeting T-cell bispecific antibody with a 2+1 format, for the treatment of multiple myeloma. Blood. 9 January 2025. DOI: 10.1182/blood.2024025987.

Impacto: 21.0. Cuartil: Q1 (1er decil)

Silva-Pilipich N., Beloki U., Apaolaza P., Igea A., Salaberry L., Prats-Mari L., Rovira E., Ondiviela M., Gorraiz M., Lasarte J.J., Vanrell L., Smerdou C.. Targeting PD-1<sup>+</sup> T cells with small-format immunocytokines enhances IL-12 antitumor activity. Molecular Therapy. 8 January 2025. DOI: 10.1016/j.ymthe.2024.11.027.

Impacto: 12.1. Cuartil: Q1 (1er decil)

Inés S.M., Celia M.O., Lasarte J.J., Teresa L.. Optimizing protocols for human regulatory T isolation, expansion, and characterization. Methods in Cell Biology. January 2025. DOI: 10.1016/bs.mcb.2024.10.005.

Serrano A., Casares N., Trocóniz I.F., Lozano T., Lasarte J.J., Zalba S., Garrido M.J.. Foxp3 inhibitory peptide encapsulated in a novel CD25-targeted nanoliposome promotes efficient tumor regression in mice. Acta Pharmacologica Sinica. January 2025. DOI: 10.1038/s41401-024-01338-0.

Impacto: 6.9. Cuartil: Q1 (1er decil)

Vicente P., Inocêncio L.R., Ullate-Agote A., Louro A.F., Jacinto J., Gamelas B., Iglesias-García O., Martin-Uriz P.S., Aguirre-Ruiz P., Ríos-Muñoz G.R., Fernández-Santos M.E., van Mil A., Sluijter J.P.G., Prósper F., Vega M.M.M., Alves P.M., Serra M.. Billion-Scale Expansion of Functional hiPSC-Derived Cardiomyocytes in Bioreactors Through Oxygen Control and Continuous Wnt Activation. Advanced Science. 2025. DOI: 10.1002/advs.202410510.

Impacto: 14.3. Cuartil: Q1 (1er decil)

Zabaleta A., Puig N., Cedena M.T., Oliver-Caldes A., Perez J.J., Moreno C., Tamariz-Amador L.E., Rodriguez-Otero P., Prosper F., Gonzalez-Calle V., López-Corral L., Rey-Búa B., Puertas B., Mirás F., Sánchez-Pina J.M., López-Muñoz N., Juan M., González-Navarro E.A., Urbano Á., de Larrea C.F., Blade J., Lahuerta J.J., Martinez-Lopez J., Mateos M.V., San Miguel J.F., Paiva B.. Clinical significance of complete remission and measurable residual disease in relapsed/refractory multiple myeloma patients treated with T-cell redirecting immunotherapy. American Journal of Hematology. January 2025. DOI: 10.1002/ajh.27526.

Impacto: 10.1. Cuartil: Q1 (1er decil)

Justicia-Lirio P., Tristán-Manzano M., Maldonado-Pérez N., Barbero-Jiménez C., Cortijo-Gutiérrez M., Pavlovic K., Molina-Estevez F.J., Muñoz P., Hinckley-Boned A., Rodriguez-Madoz J.R., Prosper F., Griñán-Lison C., Navarro-Marchal S.A., Panisello C., Muñoz-Ballester J., González-Sierra P.A., Herrera C., Marchal J.A., Martín F.. First-in-class transactivator-free, doxycycline-inducible IL-18-engineered CAR-T cells for relapsed/refractory B cell lymphomas. Molecular Therapy Nucleic Acids. 10 December 2024. DOI: 10.1016/j.omtn.2024.102308.

Impacto: 6.5. Cuartil: Q1

San José-Enériz E., Gimenez-Camino N., Rabal O., Garate L., Miranda E., Gómez-Echarte N., García F., Charalampopoulou S., Sáez E., Vilas-Zornoza A., San Martín-Uriz P., Valcárcel L.V., Barrena N., Alignani D., Tamariz-Amador L.E., Pérez-Ruiz A., Hilscher S., Schutkowski M., Alfonso-Pierola A., Martinez-Calle N., Larrayoz M.J., Paiva B., Calasanz M.J., Muñoz J., Isasa M., Martin-Subero J.I., Pineda-Lucena A., Oyarzabal J., Agirre X., Prósper F.. Epigenetic-based differentiation therapy for Acute Myeloid Leukemia. Nature Communications. December 2024. DOI: 10.1038/s41467-024-49784-y.

Impacto: 14.7. Cuartil: Q1 (1er decil)

Serrano G., Berastegui N., Díaz-Mazkiaran A., García-Olloqui P., Rodriguez-Res C., Huerga-Dominguez S., Ainciburu M., Vilas-Zornoza A., Martin-Uriz P.S., Aguirre-Ruiz P., Ullate-Agote A., Ariceta B., Lamo-Espinosa J.M., Acha P., Calvete O., Jimenez T., Molero A., Montoro M.J., Díez-Campelo M., Valcarcel D., Solé F., Alfonso-Pierola A., Ochoa I., Prósper F., Ezponda T., Hernaez M.. Single-cell transcriptional profile of CD34+ hematopoietic progenitor cells from del(5q) myelodysplastic syndromes and impact of lenalidomide. Nature Communications. December 2024. DOI: 10.1038/s41467-024-49529-x.

Impacto: 14.7. Cuartil: Q1 (1er decil)

Giles E., Heifets A., Artía Z., Inde Z., Liu Z., Zhang Z., Wang Z., Su Z., Chung Z., Frangos Z.J., Li Y., Yen Y., Sidorova Y.A., Tse-Dinh Y.C., He Y., Tang Y., Li Y., Pérez-Pertejo Y., Gupta Y.K., Zhu Y., Sun Y., Li Y., Chen Y., Aldhamen Y.A., Hu Y., Zhang Y.J., Zhang X., Yuan X., Wang X., Qin X., Yu X., Xu X., Qi X., Lu X., Wu X., Blanchet X., Foong W.E., Bradshaw W.J., Gerwick W.H., Kerr W.G., Hahn W.C., Donaldson W.A., Van Voorhis W.C., Zhang W., Tang W., Li W., Houry W.A., Lowther W.T., Clayton W.B., Van Hung Le V., Ronchi V.P., Woods V.A., Scoffone V.C., Maltarollo V.G., Dolce V., Maranda V., Segers V.F.M., Namasivayam V., Gunasekharan V., Robinson V.L., Banerji V., Tandon V., Thai V.C., Pai V.P., Desai U.R., Baumann U., Chou T.F., Chou T., O’Mara T.A., Banjo T., Su T., Lan T., Ogunwa T.H., Hermle T., Corson T.W., O’Meara T.R., Kotzé T.J., Herdendorf T.J., Richardson T.I., Kampourakis T., Gillingwater T.H., Jayasinghe T.D., Teixeira T.R., Ikegami T., Moreda T.L., Haikarainen T., Akopian T., Abaffy T., Swart T., Mehlman T., Teramoto T., Azeem S.M., Dallman S., Brady-Kalnay S.M., Sarilla S., Van Doren S.R., Marx S.O., Olson S.H., Poirier S., Waggoner S.N.. Correction to: AI is a viable alternative to high throughput screening: a 318-target study (Scientific Reports, (2024), 14, 1, (7526), 10.1038/s41598-024-54655-z). Scientific Reports. December 2024. DOI: 10.1038/s41598-024-70321-w.

Impacto: 3.8. Cuartil: Q1

Vicente P., Almeida J.I., Crespo I.E., Virgolini N., Isidro I.A., Calleja-Cervantes M.E., Rodriguez-Madoz J.R., Prosper F., Alves P.M., Serra M.. Oxygen control in bioreactor drives high yield production of functional hiPSC-like hepatocytes for advanced liver disease modelling. Scientific Reports. December 2024. DOI: 10.1038/s41598-024-75582-z.

Impacto: 3.8. Cuartil: Q1

Nunes S.P., Morales L., Rubio C., Munera-Maravilla E., Lodewijk I., Suárez-Cabrera C., Martínez V.G., Pérez-Escavy M., Pérez-Crespo M., Alonso Sánchez M., Montesinos E., San José-Enériz E., Agirre X., Prósper F., Pineda-Lucena A., Henrique R., Dueñas M., Correia M.P., Jerónimo C., Paramio J.M.. Modulation of tumor microenvironment by targeting histone acetylation in bladder cancer. Cell Death Discovery. December 2024. DOI: 10.1038/s41420-023-01786-3.

Impacto: 6.1. Cuartil: Q1

Wallach I., Bernard D., Nguyen K., Ho G., Morrison A., Stecula A., Rosnik A., O’Sullivan A.M., Davtyan A., Samudio B., Thomas B., Worley B., Butler B., Laggner C., Thayer D., Moharreri E., Friedland G., Truong H., van den Bedem H., Ng H.L., Stafford K., Sarangapani K., Giesler K., Ngo L., Mysinger M., Ahmed M., Anthis N.J., Henriksen N., Gniewek P., Eckert S., de Oliveira S., Suterwala S., PrasadPrasad S.V.K., Shek S., Contreras S., Hare S., Palazzo T., O’Brien T.E., Van Grack T., Williams T., Chern T.R., Kenyon V., Lee A.H., Cann A.B., Bergman B., Anderson B.M., Cox B.D., Warrington J.M., Sorenson J.M., Goldenberg J.M., Young M.A., DeHaan N., Pemberton R.P., Schroedl S., Abramyan T.M., Gupta T., Mysore V., Presser A.G., Ferrando A.A., Andricopulo A.D., Ghosh A., Ayachi A.G., Mushtaq A., Shaqra A.M., Toh A.K.L., Smrcka A.V., Ciccia A., de Oliveira A.S., Sverzhinsky A., de Sousa A.M., Agoulnik A.I., Kushnir A., Freiberg A.N., Statsyuk A.V., Gingras A.R., Degterev A., Tomilov A., Vrielink A., Garaeva A.A., Bryant-Friedrich A., Caflisch A., Patel A.K., Rangarajan A.V., Matheeussen A., Battistoni A., Caporali A., Chini A., Ilari A., Mattevi A., Foote A.T., Trabocchi A., Stahl A., Herr A.B., Berti A., Freywald A., Reidenbach A.G., Lam A., Cuddihy A.R., White A., Taglialatela A.. AI is a viable alternative to high throughput screening: a 318-target study. Scientific Reports. December 2024. DOI: 10.1038/s41598-024-54655-z.

Impacto: 3.8. Cuartil: Q1

Valcárcel L.V., San José-Enériz E., Ordoñez R., Apaolaza I., Olaverri-Mendizabal D., Barrena N., Valcárcel A., Garate L., San Miguel J., Pineda-Lucena A., Agirre X., Prósper F., Planes F.J.. An automated network-based tool to search for metabolic vulnerabilities in cancer. Nature Communications. December 2024. DOI: 10.1038/s41467-024-52725-4.

Impacto: 14.7. Cuartil: Q1 (1er decil)

Martinez-Verbo L., Veselinova Y., Llinàs-Arias P., García-Prieto C.A., Noguera-Castells A., Pato M.L., Bueno-Costa A., Campillo-Marcos I., Villanueva L., Oliver-Caldes A., Cardus O., Salsench S.V., García-Ortiz A., Valeri A., Rojas E.A., Barrena N., Gutiérrez N.C., Prósper F., Agirre X., Fernández de Larrea C., Martínez-López J., Ferrer G., Esteller M.. PVR (CD155) epigenetic status mediates immunotherapy response in multiple myeloma. Leukemia. December 2024. DOI: 10.1038/s41375-024-02419-z.

Impacto: 12.8. Cuartil: Q1 (1er decil)

Martín-Sánchez E., Tamariz-Amador L.E., Guerrero C., Zherniakova A., Zabaleta A., Maia C., Blanco L., Alignani D., Fortuño M.A., Grande C., Manubens A., Arguiñano J.M., Gomez C., Perez-Persona E., Olazabal I., Oiartzabal I., Panizo C., Prosper F., San-Miguel J.F., Rodriguez-Otero P., Paiva B.. Immune dysfunction prior to and during vaccination in multiple myeloma: a case study based on COVID-19. Blood Cancer Journal. December 2024. DOI: 10.1038/s41408-024-01089-5.

Impacto: 12.9. Cuartil: Q1 (1er decil)

Palacios-Berraquero M.L., Rodriguez-Marquez P., Calleja-Cervantes M.E., Berastegui N., Zabaleta A., Burgos L., Alignani D., Martin-Uriz P.S., Vilas-Zornoza A., Rodriguez-Diaz S., Inoges S., Lopez-Diaz de Cerio A., Huerga S., Tamariz E., Rifon J., Alfonso-Pierola A., Lasarte J.J., Paiva B., Hernaez M., Rodriguez-Otero P., San-Miguel J., Ezponda T., Rodriguez-Madoz J.R., Prosper F.. Molecular mechanisms promoting long-term cytopenia after BCMA CAR-T therapy in multiple myeloma. Blood Advances. 12 November 2024. DOI: 10.1182/bloodadvances.2023012522.

Impacto: 7.4. Cuartil: Q1

Garbayo E., El Moukhtari S.H., Rodríguez-Nogales C., Agirre X., Rodriguez-Madoz J.R., Rodriguez-Marquez P., Prósper F., Couvreur P., Blanco-Prieto M.J.. Rna-loaded nanoparticles for the treatment of hematological cancers. Advanced Drug Delivery Reviews. November 2024. DOI: 10.1016/j.addr.2024.115448.

Impacto: 15.2. Cuartil: Q1 (1er decil)

Exposito F., Redrado M., Serrano D., Calabuig-Fariñas S., Bao-Caamano A., Gallach S., Jantus-Lewintre E., Diaz-Lagares A., Rodriguez-Casanova A., Sandoval J., San Jose-Eneriz E., Garcia J., Redin E., Senent Y., Leon S., Pio R., Lopez R., Oyarzabal J., Pineda-Lucena A., Agirre X., Montuenga L.M., Prosper F., Calvo A.. G9a/DNMT1 co-targeting inhibits non-small cell lung cancer growth and reprograms tumor cells to respond to cancer-drugs through SCARA5 and AOX1. Cell Death and Disease. November 2024. DOI: 10.1038/s41419-024-07156-w.

Impacto: 8.1. Cuartil: Q1

Serrano A., Zalba S., Lasarte J.J., Troconiz I.F., Riva N., Garrido M.J.. Quantitative Approach to Explore Regulatory T Cell Activity in Immuno-Oncology. Pharmaceutics. November 2024. DOI: 10.3390/pharmaceutics16111461.

Impacto: 4.9. Cuartil: Q1

Ortiz de Landazuri I., Oliver-Caldés A., Español-Rego M., Agulló C., Contreras M.T., Zabaleta A., Puig N., Cabañas V., González-Calle V., Zugasti I., Inogés S., Rodríguez Otero P., Martin-Antonio B., Reguera J.L., López-Diaz de Cerio A., Aróstegui J.I., Uribe-Herranz M., Benítez-Ribas D., Rodríguez-Lobato L.G., González E.A., Tovar N., Charry P., Navarro S., Rosiñol L., Tréboles K., Mora G., Yagüe J., Moraleda J.M., Urbano-Ispizua Á., Mateos M.V., Pascal M., Paiva B., Juan M., Fernández de Larrea C.. Serum mass spectrometry for treatment monitoring in patients with multiple myeloma receiving ARI0002h CAR T-cells. British Journal of Haematology. October 2024. DOI: 10.1111/bjh.19589.

Impacto: 5.1. Cuartil: Q1

Pérez-Araluce M., Cianciosi A., Iglesias-García O., Jüngst T., Sanmartín C., Navarro-Blasco Í., Prósper F., Plano D., Mazo M.M.. Pristine Photopolymerizable Gelatin Hydrogels: A Low-Cost and Easily Modifiable Platform for Biomedical Applications †. Antioxidants. October 2024. DOI: 10.3390/antiox13101238.

Impacto: 6.0. Cuartil: Q1

Garreta E., Moya-Rull D., Marco A., Amato G., Ullate-Agote A., Tarantino C., Gallo M., Esporrín-Ubieto D., Centeno A., Vilas-Zornoza A., Mestre R., Kalil M., Gorroñogoitia I., Zaldua A.M., Sanchez S., Izquierdo Reyes L., Fernández-Santos M.E., Prosper F., Montserrat N.. Natural Hydrogels Support Kidney Organoid Generation and Promote In Vitro Angiogenesis. Advanced Materials. 22 August 2024. DOI: 10.1002/adma.202400306.

Impacto: 27.4. Cuartil: Q1 (1er decil)

Martín-Sánchez E., Blanco L., Kim P.S., Bisht K., Wang H., Van de Velde H., Jelinek T., Simoes C., Prosper F., San Miguel J.F., Alfonso A., Bergua J., Rodríguez-Veiga R., Vives S., Martínez-Cuadrón D., Montesinos P., Paiva B., Zabaleta A.. Targeting CD38 with isatuximab and a novel CD38/CD3×CD28 trispecific T-cell engager in older patients with acute myeloid leukemia. Blood Advances. 13 August 2024. DOI: 10.1182/bloodadvances.2024013212.

Impacto: 7.4. Cuartil: Q1

Gereka A., Urtaza U., Larreategi P., Prosper F., Andreu E.J., Zaldua A.M.. A Bioreactor for Celullarised Membrane Culture and Delivery under Sterile Conditions. Bioengineering. August 2024. DOI: 10.3390/bioengineering11080785.

Impacto: 3.8. Cuartil: Q2

Zawiślak A., Woźniak K., Tartaglia G., Agirre X., Gupta S., Kawala B., Znamirowska-Bajowska A., Grocholewicz K., Prosper F., Lubiński J., Jakubowska A.. Single-Nucleotide Polymorphisms in WNT Genes in Patients with Non-Syndromic Orofacial Clefts in a Polish Population. Diagnostics. July 2024. DOI: 10.3390/diagnostics14141537.

Impacto: 3.0. Cuartil: Q1

Sánchez-Moreno I., Lasarte-Cia A., Martín-Otal C., Casares N., Navarro F., Gorraiz M., Sarrión P., Hervas-Stubbs S., Jordana L., Rodriguez-Madoz J.R., San Miguel J., Prosper F., Lasarte J.J., Lozano T.. Tethered IL15-IL15Rα augments antitumor activity of CD19 CAR-T cells but displays long-term toxicity in an immunocompetent lymphoma mouse model. Journal for ImmunoTherapy of Cancer. 1 July 2024. DOI: 10.1136/jitc-2023-008572.

Impacto: 10.3. Cuartil: Q1 (1er decil)

Lamo-Espinosa J.M., Gómez-Álvarez J., Pascual Roquet-Jalmar E., Iribarren A., Recke A., Roa M.C., Valentí-Azcárate A., Granero-Moltó F., San-Julián M.. Femoroacetabular Impingement and the Effect of Osteochondroplasty on Hip Osteoarthritis Prevention: The Pandora’s Box Opening Process. Cartilage. June 2024. DOI: 10.1177/19476035231191202.

Impacto: 2.7. Cuartil: Q1

Casares N., Cuadrado-Tejedor M., García-Osta A., Lasarte J.J.. The immune system: uncharted pathways between senses and the brain. Neural Regeneration Research. June 2024. DOI: 10.4103/1673-5374.385874.

Impacto: 5.9. Cuartil: Q1

Oliver-Caldes A., Español-Rego M., Zabaleta A., González-Calle V., Navarro-Velázquez S., Inogés S., López-Díaz de Cerio A., Cabañas V., López-Muñoz N., Rodríguez-Otero P., Reguera J.L., Moreno D.F., Martínez-Cibrian N., López-Corral L., Pérez-Amill L., Martin-Antonio B., Rosiñol L., Cid J., Tovar N., Sáez-Peñataro J., López-Parra M., Olesti E., Guillén E., Varea S., Rodríguez-Lobato L.G., Battram A.M., González M.S., Sánchez-Salinas A., González-Navarro A., Ortiz-Maldonado V., Delgado J., Prósper F., Juan M., Martínez-López J., Moraleda J.M., Mateos M.V., Urbano-Ispizua Á., Paiva B., Pascal M., de Larrea C.F.. Biomarkers of Efficacy and Safety of the Academic BCMA-CART ARI0002h for the Treatment of Refractory Multiple Myeloma. Clinical Cancer Research. 15 May 2024. DOI: 10.1158/1078-0432.CCR-23-3759.

Impacto: 10.0. Cuartil: Q1

Ghobrial I.M., Gormley N., Kumar S.K., Mateos M.V., Bergsagel P.L., Chesi M., Dhodapkar M.V., Dispenzieri A., Fonseca R., Getz G., Kastritis E., Kristinsson S.Y., Martinez-Climent J.A., Manier S., Marinac C.R., Maura F., Morgan G.J., Davies F.E., Nadeem O., Nuvolone M., Paiva B., O’Donnell E., Prosper F., Shah U.A., Sklavenitis-Pistofidis R., Sperling A.S., Vassiliou G.S., Munshi N.C., Castle P.E., Anderson K.C., San Miguel J.F.. Round Table Discussion on Optimal Clinical Trial Design in Precursor Multiple Myeloma. Blood Cancer Discovery. 1 May 2024. DOI: 10.1158/2643-3230.BCD-24-0022.

Silva-Pilipich N., Lasarte-Cía A., Lasarte J.J., Smerdou C.. DNA electroporation in a vacuum: A “shocking” innovation for vaccines. Molecular Therapy Nucleic Acids. 12 March 2024. DOI: 10.1016/j.omtn.2023.102110.

Impacto: 6.5. Cuartil: Q1

Hato L., Vizcay A., Eguren I., Pérez-Gracia J.L., Rodríguez J., Gállego Pérez-Larraya J., Sarobe P., Inogés S., Díaz de Cerio A.L., Santisteban M.. Dendritic Cells in Cancer Immunology and Immunotherapy. Cancers. March 2024. DOI: 10.3390/cancers16050981.

Impacto: 4.5. Cuartil: Q1

Rosales R.M., Mountris K.A., Oliván-Viguera A., Pérez-Zabalza M., Cedillo-Servin G., Iglesias-García O., Hrynevich A., Castilho M., Malda J., Prósper F., Doblaré M., Mazo M.M., Pueyo E.. Experimentally-guided in silico design of engineered heart tissues to improve cardiac electrical function after myocardial infarction. Computers in Biology and Medicine. March 2024. DOI: 10.1016/j.compbiomed.2024.108044.

Impacto: 7.0. Cuartil: Q1 (1er decil)

Massoni-Badosa R., Aguilar-Fernández S., Nieto J.C., Soler-Vila P., Elosua-Bayes M., Marchese D., Kulis M., Vilas-Zornoza A., Bühler M.M., Rashmi S., Alsinet C., Caratù G., Moutinho C., Ruiz S., Lorden P., Lunazzi G., Colomer D., Frigola G., Blevins W., Romero-Rivero L., Jiménez-Martínez V., Vidal A., Mateos-Jaimez J., Maiques-Diaz A., Ovejero S., Moreaux J., Palomino S., Gomez-Cabrero D., Agirre X., Weniger M.A., King H.W., Garner L.C., Marini F., Cervera-Paz F.J., Baptista P.M., Vilaseca I., Rosales C., Ruiz-Gaspà S., Talks B., Sidhpura K., Pascual-Reguant A., Hauser A.E., Haniffa M., Prosper F., Küppers R., Gut I.G., Campo E., Martin-Subero J.I., Heyn H.. An atlas of cells in the human tonsil. Immunity. 13 February 2024. DOI: 10.1016/j.immuni.2024.01.006.

Impacto: 25.5. Cuartil: Q1 (1er decil)

Paz-Artigas L., González-Lana S., Polo N., Vicente P., Montero-Calle P., Martínez M.A., Rábago G., Serra M., Prósper F., Mazo M.M., González A., Ochoa I., Ciriza J.. Generation of Self-Induced Myocardial Ischemia in Large-Sized Cardiac Spheroids without Alteration of Environmental Conditions Recreates Fibrotic Remodeling and Tissue Stiffening Revealed by Constriction Assays. ACS Biomaterials Science and Engineering. 12 February 2024. DOI: 10.1021/acsbiomaterials.3c01302.

Impacto: 5.4. Cuartil: Q2

Vercher E., Covo-Vergara Á., Conde E., Hernández-Rueda M., Elizalde E., Mancheño U., Glez-Vaz J., Tamayo-Uria I., García-García M.R., Ferrer-Roig M., Marañón-Lopez J., Repáraz D., Ruiz M., López-Díaz De Cerio A., Inogés S., Iñarrairaegui M., Lasarte J.J., Sangro B., Sarobe P., Hervas-Stubbs S.. Human T cells engineered with an HLA-A2-restricted murine T-cell receptor targeting Glypican 3 effectively control human hepatocellular carcinoma in mice. Hepatology. 2024. DOI: 10.1097/HEP.0000000000001175.

Impacto: 12.9. Cuartil: Q1 (1er decil)

Gil-Melgosa L., Llombart-Blanco R., Extramiana L., Lacave I., Abizanda G., Miranda E., Agirre X., Prósper F., Pineda-Lucena A., Pons-Villanueva J., Pérez-Ruiz A.. HDACi vorinostat protects muscle from degeneration after acute rotator cuff injury in mice. Bone and Joint Research. 2024. DOI: 10.1302/2046-3758.134.BJR-2023-0292.R1.

Impacto: 4.7. Cuartil: Q1 (1er decil)

Perez-Araluce M., Jüngst T., Sanmartin C., Prosper F., Plano D., Mazo M.M.. Biomaterials-Based Antioxidant Strategies for the Treatment of Oxidative Stress Diseases. Biomimetics. January 2024. DOI: 10.3390/biomimetics9010023.

Impacto: 3.4. Cuartil: Q1

Botella-Asunción P., Rivero-Buceta E.M., Vidaurre-Agut C., Lama R., Rey-Campos M., Moreno A., Mendoza L., Mingo-Casas P., Escribano-Romero E., Gutierrez-Adan A., Saiz J.C., Smerdou C., Gonzalez G., Prosper F., Argemí J., Miguel J.S., Sanchez-Cordón P.J., Figueras A., Quesada-Gomez J.M., Novoa B., Montoya M., Martín-Acebes M.A., Pineda-Lucena A., Benlloch J.M.. AG5 is a potent non-steroidal anti-inflammatory and immune regulator that preserves innate immunity. Biomedicine and Pharmacotherapy. 31 December 2023. DOI: 10.1016/j.biopha.2023.115882.

Impacto: 6.9. Cuartil: Q1 (1er decil)

Coppiello G., Barlabé P., Moya-Jódar M., Abizanda G., Pogontke C., Barreda C., Iglesias E., Linares J., Arellano-Viera E., Larequi E., San Martín-Úriz P., Carvajal-Vergara X., Pelacho B., Mazo M.M., Pérez-Pomares J.M., Ruiz-Villalba A., Ullate-Agote A., Prósper F., Aranguren X.L.. Generation of heart and vascular system in rodents by blastocyst complementation. Developmental Cell. 18 December 2023. DOI: 10.1016/j.devcel.2023.10.008.

Impacto: 10.7. Cuartil: Q1 (1er decil)

Cavazza A., Hendel A., Bak R.O., Rio P., Güell M., Lainšček D., Arechavala-Gomeza V., Peng L., Hapil F.Z., Harvey J., Ortega F.G., Gonzalez-Martinez C., Lederer C.W., Mikkelsen K., Gasiunas G., Kalter N., Gonçalves M.A.F.V., Petersen J., Garanto A., Montoliu L., Maresca M., Seemann S.E., Gorodkin J., Mazini L., Sanchez R., Rodriguez-Madoz J.R., Maldonado-Pérez N., Laura T., Schmueck-Henneresse M., Maccalli C., Grünewald J., Carmona G., Kachamakova-Trojanowska N., Miccio A., Martin F., Turchiano G., Cathomen T., Luo Y., Tsai S.Q., Benabdellah K.. Progress and harmonization of gene editing to treat human diseases: Proceeding of COST Action CA21113 GenE-HumDi. Molecular Therapy Nucleic Acids. 12 December 2023. DOI: 10.1016/j.omtn.2023.102066.

Impacto: 6.5. Cuartil: Q1

Aparicio B., Lasarte J.J., Sarobe P.. Mutated trimeric RBD vaccines: a platform against variants of concern. Signal Transduction and Targeted Therapy. December 2023. DOI: 10.1038/s41392-023-01426-3.

Impacto: 40.8. Cuartil: Q1 (1er decil)

Romero-Torrecilla J.A., Lamo-Espinosa J.M., Ripalda-Cemboráin P., López-Martínez T., Abizanda G., Riera-Álvarez L., de Galarreta-Moriones S.R., López-Barberena A., Rodríguez-Flórez N., Elizalde R., Jayawarna V., Valdés-Fernández J., de Anleo M.E.G., Childs P., de Juan-Pardo E., Salmeron-Sanchez M., Prósper F., Muiños-López E., Granero-Moltó F.. An engineered periosteum for efficient delivery of rhBMP-2 and mesenchymal progenitor cells during bone regeneration. npj Regenerative Medicine. December 2023. DOI: 10.1038/s41536-023-00330-2.

Impacto: 6.4. Cuartil: Q1

Pitchaimani A., Ferreira M., Palange A., Pannuzzo M., De Mei C., Spano R., Marotta R., Pelacho B., Prosper F., Decuzzi P.. Compartmentalized drug localization studies in extracellular vesicles for anticancer therapy. Nanoscale Advances. 8 November 2023. DOI: 10.1039/d3na00207a.

Impacto: 4.6. Cuartil: Q2

Perez-Estenaga I., Chevalier M.T., Peña E., Abizanda G., Alsharabasy A.M., Larequi E., Cilla M., Perez M.M., Gurtubay J., Garcia-Yebenes Castro M., Prosper F., Pandit A., Pelacho B.. A Multimodal Scaffold for SDF1 Delivery Improves Cardiac Function in a Rat Subacute Myocardial Infarct Model. ACS Applied Materials and Interfaces. 8 November 2023. DOI: 10.1021/acsami.3c04245.

Impacto: 8.3. Cuartil: Q1

Cortés A., Marqués J., Pejenaute Á., Ainzúa E., Ansorena E., Abizanda G., Prósper F., de Miguel C., Zalba G.. Endothelial NOX5 overexpression induces changes in the cardiac gene profile: potential impact in myocardial infarction?. Journal of Physiology and Biochemistry. November 2023. DOI: 10.1007/s13105-023-00975-z.

Impacto: 3.7. Cuartil: Q1

Lasaga M., Río P., Vilas-Zornoza A., Planell N., Navarro S., Alignani D., Fernández-Varas B., Mouzo D., Zubicaray J., Pujol R.M., Nicoletti E., Schwartz J.D., Sevilla J., Ainciburi M., Ullate- Agote A., Surrallés J., Perona R., Sastre L., Prosper F., Gomez-Cabrero D., Bueren J.A.. Gene therapy restores the transcriptional program of hematopoietic stem cells in Fanconi anemia. Haematologica. October 2023. DOI: 10.3324/haematol.2022.282418.

Impacto: 8.2. Cuartil: Q1

Shiroud Heidari B., Lopez E.M., Chen P., Ruan R., Vahabli E., Davachi S.M., Granero-Moltó F., De-Juan-Pardo E.M., Zheng M., Doyle B.. Silane-modified hydroxyapatite nanoparticles incorporated into polydioxanone/poly(lactide-co-caprolactone) creates a novel toughened nanocomposite with improved material properties and in vivo inflammatory responses. Materials Today Bio. October 2023. DOI: 10.1016/j.mtbio.2023.100778.

Impacto: 8.7. Cuartil: Q1 (1er decil)

Clavería-Cabello A., Herranz J.M., Latasa M.U., Arechederra M., Uriarte I., Pineda-Lucena A., Prosper F., Berraondo P., Alonso C., Sangro B., García Marin J.J., Martinez-Chantar M.L., Ciordia S., Corrales F.J., Francalanci P., Alaggio R., Zucman-Rossi J., Indersie E., Cairo S., Domingo-Sàbat M., Zanatto L., Sancho-Bru P., Armengol C., Berasain C., Fernandez-Barrena M.G., Avila M.A.. Identification and experimental validation of druggable epigenetic targets in hepatoblastoma. Journal of Hepatology. October 2023. DOI: 10.1016/j.jhep.2023.05.031.

Impacto: 26.8. Cuartil: Q1 (1er decil)

Aguilar S., García-Olloqui P., Amigo-Morán L., Torán J.L., López J.A., Albericio G., Abizanda G., Herrero D., Vales Á., Rodríguez-Diaz S., Higuera M., García-Martín R., Vázquez J., Mora C., González-Aseguinolaza G., Prosper F., Pelacho B., Bernad A.. Cardiac Progenitor Cell Exosomal miR-935 Protects against Oxidative Stress. Cells. September 2023. DOI: 10.3390/cells12182300.

Impacto: 5.1. Cuartil: Q2

Marin-Bejar O., Romero-Moya D., Rodriguez-Ubreva J., Distefano M., Lessi F., Aretini P., Liquori A., Castaño J., Kozyra E., Kotmayer L., Bueno C., Cervera J., Rodriguez-Gallego J.C., Nomdedeu J.F., Murillo- Sanjuán L., de Heredia C.D., Pérez-Martinez A., López-Cadenas F., Martínez-Laperche C., Dorado-Herrero N., Marco F.M., Prósper F., Menendez P., Valcárcel D., Ballestar E., Bödör C., Bigas A., Catalá A., Wlodarski M.W., Giorgetti A.. Epigenome profiling reveals aberrant DNA methylation signature in GATA2 deficiency. Haematologica. September 2023. DOI: 10.3324/haematol.2022.282305.

Impacto: 8.2. Cuartil: Q1

Montero-Calle P., Flandes-Iparraguirre M., Kuebler B., Arán B., Larequi E., Anaut I., Coppiello G., Aranguren X.L., Veiga A., Elorz M.T.B., de Yébenes M.G., Gavira J.J., Prósper F., Iglesias-García O., Vega M.M.M.. Generation of an induced pluripotent stem cell line (ESi107-A) from a transthyretin amyloid cardiomyopathy (ATTR-CM) patient carrying a p.Ser43Asn mutation in the TTR gene. Stem Cell Research. September 2023. DOI: 10.1016/j.scr.2023.103189.

Impacto: 0.8. Cuartil: Q4

Nicola Candia A.J., Garcia Fallit M., Peña Agudelo J.A., Pérez Küper M., Gonzalez N., Moreno Ayala M.A., De Simone E., Giampaoli C., Casares N., Seilicovich A., Lasarte J.J., Zanetti F.A., Candolfi M.. Targeting FOXP3 Tumor-Intrinsic Effects Using Adenoviral Vectors in Experimental Breast Cancer. Viruses. September 2023. DOI: 10.3390/v15091813.

Impacto: 3.8. Cuartil: Q2

Lara-Astiaso D., Goñi-Salaverri A., Mendieta-Esteban J., Narayan N., Del Valle C., Gross T., Giotopoulos G., Beinortas T., Navarro-Alonso M., Aguado-Alvaro L.P., Zazpe J., Marchese F., Torrea N., Calvo I.A., Lopez C.K., Alignani D., Lopez A., Saez B., Taylor-King J.P., Prosper F., Fortelny N., Huntly B.J.P.. In vivo screening characterizes chromatin factor functions during normal and malignant hematopoiesis. Nature Genetics. September 2023. DOI: 10.1038/s41588-023-01471-2.

Impacto: 31.7. Cuartil: Q1 (1er decil)

El Moukhtari S.H., Garbayo E., Amundarain A., Pascual-Gil S., Carrasco-León A., Prosper F., Agirre X., Blanco-Prieto M.J.. Lipid nanoparticles for siRNA delivery in cancer treatment. Journal of Controlled Release. September 2023. DOI: 10.1016/j.jconrel.2023.07.054.

Impacto: 10.5. Cuartil: Q1 (1er decil)

Costa M.H.G., Costa M.S., Painho B., Sousa C.D., Carrondo I., Oltra E., Pelacho B., Prosper F., Isidro I.A., Alves P., Serra M.. Enhanced bioprocess control to advance the manufacture of mesenchymal stromal cell-derived extracellular vesicles in stirred-tank bioreactors. Biotechnology and Bioengineering. September 2023. DOI: 10.1002/bit.28378.

Impacto: 3.5. Cuartil: Q2

Martinez-De-morentin X., Khan S.A., Lehmann R., Qu S., Maillo A., Kiani N.A., Prosper F., Tegner J., Gomez-Cabrero D.. LIBRA: an adaptative integrative tool for paired single-cell multi-omics data. Quantitative Biology. September 2023. DOI: 10.15302/J-QB-022-0318.

Bocanegra A., Fernández-Hinojal G., Ajona D., Blanco E., Zuazo M., Garnica M., Chocarro L., Alfaro-Arnedo E., Piñeiro-Hermida S., Morente P., Fernández L., Remirez A., Echaide M., Martinez-Aguillo M., Morilla I., Tavira B., Roncero A., Gotera C., Ventura A., Recalde N., Pichel J.G., Lasarte J.J., Montuenga L., Vera R., Pio R., Escors D., Kochan G.. Plasma fractalkine contributes to systemic myeloid diversity and PD-L1/PD-1 blockade in lung cancer. EMBO Reports. 3 August 2023. DOI: 10.15252/embr.202255884.

Impacto: 6.5. Cuartil: Q1

Exposito F., Redrado M., Houry M., Hastings K., Molero-Abraham M., Lozano T., Solorzano J.L., Sanz-Ortega J., Adradas V., Amat R., Redin E., Leon S., Legarra N., Garcia J., Serrano D., Valencia K., Robles-Oteiza C., Foggetti G., Otegui N., Felip E., Lasarte J.J., Paz-Ares L., Zugazagoitia J., Politi K., Montuenga L., Calvo A.. PTEN Loss Confers Resistance to Anti–PD-1 Therapy in Non–Small Cell Lung Cancer by Increasing Tumor Infiltration of Regulatory T Cells. Cancer Research. 1 August 2023. DOI: 10.1158/0008-5472.CAN-22-3023.

Impacto: 12.5. Cuartil: Q1 (1er decil)

Oliver-Caldés A., González-Calle V., Cabañas V., Español-Rego M., Rodríguez-Otero P., Reguera J.L., López-Corral L., Martin-Antonio B., Zabaleta A., Inogés S., Varea S., Rosiñol L., López-Díaz de Cerio A., Tovar N., Jiménez R., López-Parra M., Rodríguez-Lobato L.G., Sánchez-Salinas A., Olesti E., Calvo-Orteu M., Delgado J., Pérez-Simón J.A., Paiva B., Prósper F., Sáez-Peñataro J., Juan M., Moraleda J.M., Mateos M.V., Pascal M., Urbano-Ispizua A., Fernández de Larrea C.. Fractionated initial infusion and booster dose of ARI0002h, a humanised, BCMA-directed CAR T-cell therapy, for patients with relapsed or refractory multiple myeloma (CARTBCMA-HCB-01): a single-arm, multicentre, academic pilot study. The Lancet Oncology. August 2023. DOI: 10.1016/S1470-2045(23)00222-X.

Impacto: 41.6. Cuartil: Q1 (1er decil)

Shiroud Heidari B., Muiños Lopez E., Harrington E., Ruan R., Chen P., Davachi S.M., Allardyce B., Rajkhowa R., Dilley R., Granero-Moltó F., De-Juan-Pardo E.M., Zheng M., Doyle B.. Novel hybrid biocomposites for tendon grafts: The addition of silk to polydioxanone and poly(lactide-co-caprolactone) enhances material properties, in vitro and in vivo biocompatibility. Bioactive Materials. July 2023. DOI: 10.1016/j.bioactmat.2023.02.003.

Impacto: 18.0. Cuartil: Q1 (1er decil)

Willcockson H., Ozkan H., Valdés-Fernández J., Arbeeva L., Mucahit E., Musawwir L., Hooper L.B., Granero-Moltó F., Prósper F., Longobardi L.. CC-Chemokine Receptor-2 Expression in Osteoblasts Contributes to Cartilage and Bone Damage during Post-Traumatic Osteoarthritis. Biomolecules. June 2023. DOI: 10.3390/biom13060891.

Impacto: 4.8. Cuartil: Q1

Simoes C., Villar S., Ariceta B., Garcés J.J., Burgos L., Alignani D., Sarvide S., Martínez-Cuadrón D., Bergua J.M., Vives S., Algarra L., Tormo M., Martinez P., Serrano J., Herrera P., Ramos F., Salamero O., Lavilla E., Gil C., Lopez-Lorenzo J.L., Vidriales M.B., Chillon C., Labrador J., Falantes J.F., Sayas M.J., Ayala R., Martinez-Lopez J., Pierola A.A., Calasanz M.J., Prosper F., San-Miguel J.F., Sanz M., Paiva B., Montesinos P.. Transcriptional and genomic characterization of measurable residual disease in acute myeloid leukaemia. British Journal of Haematology. June 2023. DOI: 10.1111/bjh.18815.

Impacto: 5.1. Cuartil: Q1

Sánchez-Guijo F., Avendaño-Solá C., Badimón L., Bueren J.A., Canals J.M., Delgadillo J., Delgado J., Eguizábal C., Fernández-Santos M.E., García-Olmo D., González-Aseguinolaza G., Juan M., Martín F., Mata R., Montserrat N., Pérez-Martínez A., Pérez-Simón J.A., Prósper F., Urbano-Ispizua Á., Zapata A.G., Sureda A., Moraleda J.M.. Role of Hospital Exemption in Europe: position paper from the Spanish Advanced Therapy Network (TERAV). Bone Marrow Transplantation. June 2023. DOI: 10.1038/s41409-023-01962-0.

Impacto: 4.5. Cuartil: Q1

Ihejirika-Lomedico R., Patel K., Buchalter D.B., Kirby D.J., Mehta D., Dankert J.F., Muiños-López E., Ihejirika Y., Leucht P.. Non-psychoactive Cannabidiol Prevents Osteoporosis in an Animal Model and Increases Cell Viability, Proliferation, and Osteogenic Gene Expression in Human Skeletal Stem and Progenitor Cells. Calcified Tissue International. June 2023. DOI: 10.1007/s00223-023-01083-2.

Impacto: 3.3. Cuartil: Q2

Grilli F., Albanesi E., Pelacho B., Prosper F., Decuzzi P., Di Mascolo D.. Microstructured Polymeric Fabrics Modulating the Paracrine Activity of Adipose-Derived Stem Cells. International Journal of Molecular Sciences. June 2023. DOI: 10.3390/ijms241210123.

Impacto: 4.9. Cuartil: Q1

Perucho L., Icardi L., Di Simone E., Basso V., Agresti A., Vilas Zornoza A., Lozano T., Prosper F., Lasarte J.J., Mondino A.. The transcriptional regulator Sin3A balances IL-17A and Foxp3 expression in primary CD4 T cells. EMBO Reports. 4 May 2023. DOI: 10.15252/embr.202255326.

Impacto: 6.5. Cuartil: Q1

Silva-Pilipich N., Blanco E., Lozano T., Martisova E., Igea A., Herrador-Cañete G., Ballesteros-Briones M.C., Gorraiz M., Sarrión P., González-Sapienza G., Lasarte J.J., Vanrell L., Smerdou C.. Local delivery of optimized nanobodies targeting the PD-1/PD-L1 axis with a self-amplifying RNA viral vector induces potent antitumor responses. Cancer Letters. 1 May 2023. DOI: 10.1016/j.canlet.2023.216139.

Impacto: 9.1. Cuartil: Q1

Larrayoz M., Garcia-Barchino M.J., Celay J., Etxebeste A., Jimenez M., Perez C., Ordoñez R., Cobaleda C., Botta C., Fresquet V., Roa S., Goicoechea I., Maia C., Lasaga M., Chesi M., Bergsagel P.L., Larrayoz M.J., Calasanz M.J., Campos-Sanchez E., Martinez-Cano J., Panizo C., Rodriguez-Otero P., Vicent S., Roncador G., Gonzalez P., Takahashi S., Katz S.G., Walensky L.D., Ruppert S.M., Lasater E.A., Amann M., Lozano T., Llopiz D., Sarobe P., Lasarte J.J., Planell N., Gomez-Cabrero D., Kudryashova O., Kurilovich A., Revuelta M.V., Cerchietti L., Agirre X., San Miguel J., Paiva B., Prosper F., Martinez-Climent J.A.. Preclinical models for prediction of immunotherapy outcomes and immune evasion mechanisms in genetically heterogeneous multiple myeloma. Nature Medicine. March 2023. DOI: 10.1038/s41591-022-02178-3.

Impacto: 58.7. Cuartil: Q1 (1er decil)

Wu M., Pelacho B., Claus P., De Buck S., Veltman D., Gillijns H., Holemans P., Pokreisz P., Caluwé E., Iglesias Colino E., Cohen S., Prosper F., Janssens S.. Alginate sulfate-nanoparticles loaded with hepatocyte growth factor and insulin-like growth factor-1 improve left ventricular repair in a porcine model of myocardial ischemia reperfusion injury. European Journal of Pharmaceutics and Biopharmaceutics. March 2023. DOI: 10.1016/j.ejpb.2023.01.012.

Impacto: 4.4. Cuartil: Q1

Ozkan H., Di Francesco M., Willcockson H., Valdés-Fernández J., Di Francesco V., Granero-Moltó F., Prósper F., Decuzzi P., Longobardi L.. Sustained inhibition of CC-chemokine receptor-2 via intraarticular deposition of polymeric microplates in post-traumatic osteoarthritis. Drug Delivery and Translational Research. February 2023. DOI: 10.1007/s13346-022-01235-1.

Impacto: 5.7. Cuartil: Q1

Mejías Sosa L., López-Janeiro Á., Córdoba Iturriagagoitia A., Sala P., Solans B.P., Hato L., Inogés S., López-Díaz de Cerio A., Guillén-Grima F., Espinós J., De La Cruz S., Lozano M.D., Idoate M.A., Santisteban M.. Modification of Breast Cancer Milieu with Chemotherapy plus Dendritic Cell Vaccine: An Approach to Select Best Therapeutic Strategies. Biomedicines. February 2023. DOI: 10.3390/biomedicines11020238.

Impacto: 3.9. Cuartil: Q1

Mateos M.V., Prosper F., Martin Sánchez J., Ocio E.M., Oriol A., Motlló C., Michot J.M., Jarque I., Iglesias R., Solé M., Martínez S., Kahatt C., Fudio S., Corral G., Zeaiter A., Montilla L., Ribrag V.. Phase I study of plitidepsin in combination with bortezomib and dexamethasone in patients with relapsed/refractory multiple myeloma. Cancer Medicine. February 2023. DOI: 10.1002/cam4.5250.

Impacto: 2.9. Cuartil: Q2

Aparicio B., Ruiz M., Casares N., Silva L., Egea J., Pérez P., Albericio G., Esteban M., García-Arriaza J., Lasarte J.J., Sarobe P.. Enhanced cross-recognition of SARS-CoV-2 Omicron variant by peptide vaccine-induced antibodies. Frontiers in Immunology. 24 January 2023. DOI: 10.3389/fimmu.2022.1044025.

Impacto: 5.7. Cuartil: Q1

Stölzel F., Fordham S.E., Nandana D., Lin W.Y., Blair H., Elstob C., Bell H.L., Mohr B., Ruhnke L., Kunadt D., Dill C., Allsop D., Piddock R., Soura E.N., Park C., Fadly M., Rahman T., Alharbi A., Wobus M., Altmann H., Röllig C., Wagenführ L., Jones G.L., Menne T., Jackson G.H., Marr H.J., Fitzgibbon J., Onel K., Meggendorfer M., Robinson A., Bziuk Z., Bowes E., Heidenreich O., Haferlach T., Villar S., Ariceta B., Diaz R.A., Altschuler S.J., Wu L.F., Prosper F., Montesinos P., Martinez-Lopez J., Bornhäuser M., Allan J.M.. Biallelic TET2 mutations confer sensitivity to 5′-azacitidine in acute myeloid leukemia. JCI Insight. 24 January 2023. DOI: 10.1172/jci.insight.150368.

Impacto: 6.3. Cuartil: Q1

Ainciburu M., Ezponda T., Berastegui N., Alfonso-Pierola A., Vilas-Zornoza A., San Martin-Uriz P., Alignani D., Lamo-Espinosa J., San-Julian M., Jiménez-Solas T., Lopez F., Muntion S., Sanchez-Guijo F., Molero A., Montoro J., Serrano G., Diaz-Mazkiaran A., Lasaga M., Gomez-Cabrero D., Diez-Campelo M., Valcarcel D., Hernaez M., Romero J.P., Prosper F.. Uncovering perturbations in human hematopoiesis associated with healthy aging and myeloid malignancies at single-cell resolution. eLife. 11 January 2023. DOI: 10.7554/eLife.79363.

Impacto: 6.4. Cuartil: Q1 (1er decil)

Moya-Jódar M., Ullate-Agote A., Barlabé P., Rodríguez-Madoz J.R., Abizanda G., Barreda C., Carvajal-Vergara X., Vilas-Zornoza A., Romero J.P., Garate L., Agirre X., Coppiello G., Prósper F., Aranguren X.L.. Revealing cell populations catching the early stages of human embryo development in naive pluripotent stem cell cultures. Stem Cell Reports. 10 January 2023. DOI: 10.1016/j.stemcr.2022.11.015.

Impacto: 5.9. Cuartil: Q1

Simoes C., Chillon M.C., Martínez-Cuadrón D., Calasanz M.J., Vridiales M.B., Vazquez I., Hernández-Ruano M., Ariceta B., Aguirre-Ruiz P., Burgos L., Alignani D., Sarvide S., Villar S., Pierola A.A., Prosper F., Ayala R., Martínez-López J., Bergua Burgues J.M., Vives S., Perez-Simon J.A., Garcia-Fortes M., del Castillo T.B., Colorado M., Olave M., Rodríguez-Gutiérrez J.I., Labrador J., González M., San-Miguel J.F., Sanz M.Á., Montesinos P., Paiva B.. Integrated flow cytometry and sequencing to reconstruct evolutionary patterns from dysplasia to acute myeloid leukemia. Blood Advances. 10 January 2023. DOI: 10.1182/bloodadvances.2022008141.

Impacto: 7.4. Cuartil: Q1

Conde E., Casares N., Mancheño U., Elizalde E., Vercher E., Capozzi R., Santamaria E., Rodriguez-Madoz J.R., Prosper F., Lasarte J.J., Lozano T., Hervas-Stubbs S.. FOXP3 expression diversifies the metabolic capacity and enhances the efficacy of CD8 T cells in adoptive immunotherapy of melanoma. Molecular Therapy. 4 January 2023. DOI: 10.1016/j.ymthe.2022.08.017.

Impacto: 12.1. Cuartil: Q1 (1er decil)

Sadeghlar F., Seelemann J., Vogt A., Möhring C., Zhou T., Mahn R., Kornek M., Lukacs-Kornek V., Casares N., Lasarte J.J., Sarobe P., van Beekum C., Matthaei H., Manekeller S., Kalff J., Schmidt-Wolf I.G.H., Strassburg C.P., Gonzalez-Carmona M.A.. Regulatory T Cell Inhibition by P60 Combined with Adenoviral AFP Transduced Dendritic Cells for Immunotherapy of Hepatocellular Carcinoma. Immunological Investigations. 2023. DOI: 10.1080/08820139.2023.2261980.

Impacto: 2.9. Cuartil: Q3

Calviño C., Ceballos C., Alfonso A., Jauregui P., Calleja-Cervantes M.E., San Martin-Uriz P., Rodriguez-Marquez P., Martin-Mallo A., Iglesias E., Abizanda G., Rodriguez-Diaz S., Martinez-Turrillas R., Illarramendi J., Viguria M.C., Redondo M., Rifon J., Villar S., Lasarte J.J., Inoges S., Lopez-Diaz de Cerio A., Hernaez M., Prosper F., Rodriguez-Madoz J.R.. Optimization of universal allogeneic CAR-T cells combining CRISPR and transposon-based technologies for treatment of acute myeloid leukemia. Frontiers in Immunology. 2023. DOI: 10.3389/fimmu.2023.1270843.

Impacto: 5.7. Cuartil: Q1

Casares N., Alfaro M., Cuadrado-Tejedor M., Lasarte-Cia A., Navarro F., Vivas I., Espelosin M., Cartas-Cejudo P., Fernández-Irigoyen J., Santamaría E., García-Osta A., Lasarte J.J.. Improvement of cognitive function in wild-type and Alzheimer´s disease mouse models by the immunomodulatory properties of menthol inhalation or by depletion of T regulatory cells. Frontiers in Immunology. 2023. DOI: 10.3389/fimmu.2023.1130044.

Impacto: 5.7. Cuartil: Q1

Aparicio B., Ruiz M., Casares N., Silva L., Egea J., Pérez P., Albericio G., Esteban M., García-Arriaza J., Lasarte J.J., Sarobe P.. Erratum: Enhanced cross-recognition of SARS-CoV-2 Omicron variant by peptide vaccine-induced antibodies(Front. Immunol., (2023), 13, (1044025), 10.3389/fimmu.2022.1044025). Frontiers in Immunology. 2023. DOI: 10.3389/fimmu.2023.1172427.

Impacto: 5.7. Cuartil: Q1

Bobadilla Muñoz M., Orbe J., Abizanda G., Machado F.J.D., Vilas A., Ullate-Agote A., Extramiana L., Baraibar Churio A., Aranguren X.L., Cantero G., Sáinz Amillo N., Rodríguez J.A., Ramos García L., Romero Riojas J.P., Vallejo-Illarramendi A., Paradas C., López de Munain A., Páramo J.A., Prósper F., Pérez-Ruiz A.. Loss of the matrix metalloproteinase-10 causes premature features of aging in satellite cells. Frontiers in Cell and Developmental Biology. 2023. DOI: 10.3389/fcell.2023.1128534.

Impacto: 4.6. Cuartil: Q1

Gil-Cabrerizo P., Saludas L., Prósper F., Abizanda G., Echanove-González de Anleo M., Ruiz-Villalba A., Garbayo E., Blanco-Prieto M.J.. Development of an injectable alginate-collagen hydrogel for cardiac delivery of extracellular vesicles. International Journal of Pharmaceutics. 15 December 2022. DOI: 10.1016/j.ijpharm.2022.122356.

Impacto: 5.8. Cuartil: Q1

Berastegui N., Ainciburu M., Romero J.P., Garcia-Olloqui P., Alfonso-Pierola A., Philippe C., Vilas-Zornoza A., San Martin-Uriz P., Ruiz-Hernández R., Abarrategi A., Ordoñez R., Alignani D., Sarvide S., Castro-Labrador L., Lamo-Espinosa J.M., San-Julian M., Jimenez T., López-Cadenas F., Muntion S., Sanchez-Guijo F., Molero A., Montoro M.J., Tazón B., Serrano G., Diaz-Mazkiaran A., Hernaez M., Huerga S., Bewicke-Copley F., Rio-Machin A., Maurano M.T., Díez-Campelo M., Valcarcel D., Rouault-Pierre K., Lara-Astiaso D., Ezponda T., Prosper F.. The transcription factor DDIT3 is a potential driver of dyserythropoiesis in myelodysplastic syndromes. Nature Communications. December 2022. DOI: 10.1038/s41467-022-35192-7.

Impacto: 16.6. Cuartil: Q1 (1er decil)

Armes H., Bewicke-Copley F., Rio-Machin A., Di Bella D., Philippe C., Wozniak A., Tummala H., Wang J., Ezponda T., Prosper F., Dokal I., Vulliamy T., Kilpivaara O., Wartiovaara-Kautto U., Fitzgibbon J., Rouault-Pierre K.. Germline ERCC excision repair 6 like 2 (ERCC6L2) mutations lead to impaired erythropoiesis and reshaping of the bone marrow microenvironment. British Journal of Haematology. December 2022. DOI: 10.1111/bjh.18466.

Impacto: 6.5. Cuartil: Q1

Colyn L., Alvarez-Sola G., Latasa M.U., Uriarte I., Herranz J.M., Arechederra M., Vlachogiannis G., Rae C., Pineda-Lucena A., Casadei-Gardini A., Pedica F., Aldrighetti L., López-López A., López-Gonzálvez A., Barbas C., Ciordia S., Van Liempd S.M., Falcón-Pérez J.M., Urman J., Sangro B., Vicent S., Iraburu M.J., Prosper F., Nelson L.J., Banales J.M., Martinez-Chantar M.L., Marin J.J.G., Braconi C., Trautwein C., Corrales F.J., Cubero F.J., Berasain C., Fernandez-Barrena M.G., Avila M.A.. New molecular mechanisms in cholangiocarcinoma: signals triggering interleukin-6 production in tumor cells and KRAS co-opted epigenetic mediators driving metabolic reprogramming. Journal of Experimental and Clinical Cancer Research. December 2022. DOI: 10.1186/s13046-022-02386-2.

Impacto: 11.3. Cuartil: Q1

Peng J., Serrano G., Traniello I.M., Calleja-Cervantes M.E., Chembazhi U.V., Bangru S., Ezponda T., Rodriguez-Madoz J.R., Kalsotra A., Prosper F., Ochoa I., Hernaez M.. SimiC enables the inference of complex gene regulatory dynamics across cell phenotypes. Communications Biology. December 2022. DOI: 10.1038/s42003-022-03319-7.

Villar S., Ariceta B., Agirre X., Urribarri A.D., Ayala R., Martínez-Cuadrón D., Bergua J.M., Vives S., Algarra L., Tormo M., Martínez P., Serrano J., Simoes C., Herrera P., Calasanz M.J., Alfonso-Piérola A., Paiva B., Martínez-López J., San Miguel J.F., Prósper F., Montesinos P.. The transcriptomic landscape of elderly acute myeloid leukemia identifies B7H3 and BANP as a favorable signature in high-risk patients. Frontiers in Oncology. 24 November 2022. DOI: 10.3389/fonc.2022.1054458.

Impacto: 4.7. Cuartil: Q2

Aparicio B., Repáraz D., Ruiz M., Llopiz D., Silva L., Vercher E., Theunissen P., Tamayo I., Smerdou C., Igea A., Santisteban M., Gónzalez-Deza C., Lasarte J.J., Hervás-Stubbs S., Sarobe P.. Identification of HLA class I-restricted immunogenic neoantigens in triple negative breast cancer. Frontiers in Immunology. 2 November 2022. DOI: 10.3389/fimmu.2022.985886.

Impacto: 7.3. Cuartil: Q1

Amundarain A., Pastor F., Prósper F., Agirre X.. Aptamers, a New Therapeutic Opportunity for the Treatment of Multiple Myeloma. Cancers. November 2022. DOI: 10.3390/cancers14215471.

Impacto: 5.2. Cuartil: Q2