Investigadores
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Investigadores
Hospital Niño Jesús (HUNJM). Madrid.
Terapia Génica
Manuel Ramírez Orellana
Investigador principal
Grupo de Investigación: Hospital Niño Jesús (HUNJM). Madrid.
África González Murillo
Investigador colaborador
Grupo de Investigación: Hospital Niño Jesús (HUNJM). Madrid.
ALBA RUBIO SAN SIMÓN
Investigador colaborador
Grupo de Investigación: Hospital Niño Jesús (HUNJM). Madrid.
Elena Sebastián Pérez
Investigador colaborador
Grupo de Investigación: Hospital Niño Jesús (HUNJM). Madrid.
Gonzalo García Aguilera
Investigador colaborador
Grupo de Investigación: Hospital Niño Jesús (HUNJM). Madrid.
Javier García Castro
Investigador colaborador
Grupo de Investigación: Hospital Niño Jesús (HUNJM). Madrid.
Jesús González de Pablo
Investigador colaborador
Grupo de Investigación: Hospital Niño Jesús (HUNJM). Madrid.
Josune Zubicaray Salegui
Investigador colaborador
Grupo de Investigación: Hospital Niño Jesús (HUNJM). Madrid.
Julián Sevilla Navarro
Investigador colaborador
Grupo de Investigación: Hospital Niño Jesús (HUNJM). Madrid.
June Iriondo Alzola
Investigador colaborador
Grupo de Investigación: Hospital Niño Jesús (HUNJM). Madrid.
Lorena García García
Investigador colaborador
Grupo de Investigación: Hospital Niño Jesús (HUNJM). Madrid.
Mora J., Chan G.C.F., Morgenstern D.A., Amoroso L., Nysom K., Faber J., Wingerter A., Bear M.K., Rubio-San-Simon A., de Las Heras B.M., Tornøe K., Düring M., Kushner B.H.. The anti-GD2 monoclonal antibody naxitamab plus GM-CSF for relapsed or refractory high-risk neuroblastoma: a phase 2 clinical trial. Nature Communications. December 2025. DOI: 10.1038/s41467-025-56619-x.
Impacto: 14.7. Cuartil: Q1
(1er decil)
Plaza-Florido A., Santos-Lozano A., Yanguas-Casás N., Pinós T., Fiuza-Luces C., Lucia A.. Can exercise kill tumors?. Journal of Sport and Health Science. December 2025. DOI: 10.1016/j.jshs.2024.101001.
Impacto: 9.7. Cuartil: Q1
(1er decil)
Ramírez M.J., Pujol R., Minguillón J., Bogliolo M., Persico I., Cavero D., de la Cal A., Río P., Navarro S., Casado J.A., Bailador A., de la Fuente A.S., de Heredia M.L., Almazán F., Antelo M.L., Argilés B., Badell I., Baragaño M., Beléndez C., Bermúdez M., Bernués M., Buedo M.I., Carrasco E., Català A., Costa D., Cuesta I., Fernandez-Delgado R., Fernández-Teijeiro A., Figuera Á., García M., Gondra A., González M., Muñiz S.G., Hernández-Rodríguez I., Ibañez F., Kelleher N.J., Lendínez F., López M., López-Almaraz R., Marchante I., Mendoza C., Nieto J., Ojeda E., Payán-Pernía S., Peláez I., de Soto I.P., Portugal R., Ramos-Arroyo M.A., Regueiro A., Rodríguez A., Rosell J., Saez R., Sánchez J., Sánchez M., Senent M., Tapia M., Trujillo-Quintero J.P., Vagace J.M., Verdú-Amorós J., Verdugo V., Vidales I., Villarreal J., Díaz-de-Heredia C., Sevilla J., Bueren J.A., Surrallés J.. Prognostic significance of mutation type and chromosome fragility in Fanconi anemia. American Journal of Hematology. February 2025. DOI: 10.1002/ajh.27520.
Impacto: 10.1. Cuartil: Q1
(1er decil)
Casanova M., Albert C.M., Bautista F., Borinstein S.C., Bradfield S., Bukowinski A., Campbell-Hewson Q., Hawkins D.S., Kim A., Milano G.M., Marshall L.V., Pinto N., Pratilas C.A., Rubio-San-Simón A., Windsor R., Majid O., Scott R., Jia Y., Paoletti C., Kontny U.. Efficacy, safety, and pharmacokinetics of eribulin as monotherapy or in combination with irinotecan for patients with pediatric rhabdomyosarcoma, non-rhabdomyosarcoma soft tissue sarcoma, or Ewing sarcoma. ESMO Open. February 2025. DOI: 10.1016/j.esmoop.2024.104129.
Impacto: 7.1. Cuartil: Q1
González-Novo R., Armesto M., González-Murillo Á., Dreger M., Hurlstone A.F.L., Benito A., Samaniego R., Ramírez M., Redondo-Muñoz J.. Dual effect of targeting LSD1 on the invasiveness and the mechanical response of acute lymphoblastic leukemia cells. Biomedicine and Pharmacotherapy. February 2025. DOI: 10.1016/j.biopha.2025.117830.
Impacto: 6.9. Cuartil: Q1
(1er decil)
Arroyo-Nogales A., Jimenez-Falcao S., Megias D., Ramirez M., Baeza A.. Nano-Sized Liposomes for Click-Chemistry-Based Selective Guiding of Immune Cells to Neuroblastoma. ACS Applied Nano Materials. 2025. DOI: 10.1021/acsanm.5c00475.
Impacto: 5.3. Cuartil: Q2
Ortiz-Sánchez P., González-Soto S., Villamizar L.H., Valencia J., Jiménez E., Sacedón R., Ramírez M., Fariñas I., Varas A., Fernández-Sevilla L.M., Vicente Á.. Meningeal leukaemic aggregates as foci of cell expansion and chemoresistance in acute lymphoblastic leukaemia metastasis. Cellular Oncology. 2025. DOI: 10.1007/s13402-025-01043-y.
Impacto: 4.9. Cuartil: Q1
Parra-Nieto J., Hidalgo L., Márquez-Cantudo M., García-Castro J., Megias D., Ramirez M., Baeza A.. Liposomal-Based Nanoarchitectonics as Bispecific T Cell Engagers in Neuroblastoma Therapy. ACS Applied Materials and Interfaces. 2025. DOI: 10.1021/acsami.5c00633.
Impacto: 8.3. Cuartil: Q1
Río P., Zubicaray J., Navarro S., Gálvez E., Sánchez-Domínguez R., Nicoletti E., Sebastián E., Rothe M., Pujol R., Bogliolo M., John-Neek P., Bastone A.L., Schambach A., Wang W., Schmidt M., Larcher L., Segovia J.C., Yáñez R.M., Alberquilla O., Díez B., Fernández-García M., García-García L., Ramírez M., Galy A., Lefrere F., Cavazzana M., Leblanc T., García de Andoin N., López-Almaraz R., Catalá A., Barquinero J., Rodríguez-Perales S., Rao G., Surrallés J., Soulier J., Díaz-de-Heredia C., Schwartz J.D., Sevilla J., Bueren J.A.. Haematopoietic gene therapy of non-conditioned patients with Fanconi anaemia-A: results from open-label phase 1/2 (FANCOLEN-1) and long-term clinical trials. The Lancet. 21 December 2024. DOI: 10.1016/S0140-6736(24)01880-4.
Impacto: 98.4. Cuartil: Q1
(1er decil)
Plaza-Florido A., Gálvez B.G., Lopez J.A., Santos-Lozano A., Zazo S., Rincon-Castanedo C., Martín-Ruiz A., Lumbreras J., Terron-Camero L.C., Lopez-Soto A., Andres-Leon E., González-Murillo Á., Rojo F., Ramírez M., Lucia A., Fiuza-Luces C.. Exercise and tumor proteome: insights from a neuroblastoma model. Physiological Genomics. Dec 2024. DOI: 10.1152/physiolgenomics.00064.2024.
Impacto: 2.5. Cuartil: Q2
Sánchez R., Dorado S., Ruíz-Heredia Y., Martín-Muñoz A., Rosa-Rosa J.M., Ribera J., García O., Jimenez-Ubieto A., Carreño-Tarragona G., Linares M., Rufián L., Juárez A., Carrillo J., Espino M.J., Cáceres M., Expósito S., Cuevas B., Vanegas R., Casado L.F., Torrent A., Zamora L., Mercadal S., Coll R., Cervera M., Morgades M., Hernández-Rivas J.Á., Bravo P., Serí C., Anguita E., Barragán E., Sargas C., Ferrer-Marín F., Sánchez-Calero J., Sevilla J., Ruíz E., Villalón L., del Mar Herráez M., Riaza R., Magro E., Steegman J.L., Wang C., de Toledo P., García-Gutiérrez V., Ayala R., Ribera J.M., Barrio S., Martínez-López J.. Correction to: Detection of kinase domain mutations in BCR::ABL1 leukemia by ultra-deep sequencing of genomic DNA (Scientific Reports, (2022), 12, 1, (13057), 10.1038/s41598-022-17271-3). Scientific Reports. December 2024. DOI: 10.1038/s41598-024-57570-5.
Impacto: 3.8. Cuartil: Q1
Bhatla T., Hogan L.E., Teachey D.T., Bautista F., Moppett J., Velasco Puyó P., Micalizzi C., Rossig C., Shukla N., Gilad G., Locatelli F., Baruchel A., Zwaan C.M., Bezler N.S., Rubio-San-Simón A., Taussig D.C., Raetz E.A., Mao Z.J., Wood B.L., Alvarez Arias D., Krevvata M., Nnane I., Bandyopadhyay N., Lopez Solano L., Dennis R.M., Carson R., Vora A.. Daratumumab in pediatric relapsed/refractory acute lymphoblastic leukemia or lymphoblastic lymphoma: the DELPHINUS study. Blood. 21 November 2024. DOI: 10.1182/blood.2024024493.
Impacto: 21.0. Cuartil: Q1
(1er decil)
García-Aguilera G., Castillo-Robleda A., Sanz A., Ramírez M.. Validation of a Spectral Flow Cytometry Single-Tube Panel for the Clinical Diagnosis and Follow-Up of Children and Adolescents with B-Cell Acute Lymphoblastic Leukemia. Cells. November 2024. DOI: 10.3390/cells13221891.
Impacto: 5.1. Cuartil: Q2
Pennesi E., Brivio E., Ammerlaan A.C.J., Jiang Y., van der Velden V.H.J., Beverloo H.B., Sleight B., Locatelli F., Brethon B., Rossig C., Engstler G., Nilsson A., Bruno B., Petit A., Bielorai B., Rizzari C., Rialland F., Rubio-San-Simón A., Bautista Sirvent F.J., Diaz-De-Heredia C., Rives S., Zwaan C.M.. Inotuzumab ozogamicin combined with chemotherapy in pediatric B-cell precursor CD22<sup>+</sup> acute lymphoblastic leukemia: results of the phase IB ITCC-059 trial. Haematologica. October 2024. DOI: 10.3324/haematol.2023.284409.
Impacto: 8.2. Cuartil: Q1
Morales-Molina A., Rodriguez-Milla M.A., Garcia-Rodriguez P., Hidalgo L., Alemany R., Garcia-Castro J.. Deletion of the RGD motif from the penton base in oncolytic adenoviruses enhances antitumor efficacy of combined CAR T cell therapy. Molecular Therapy Oncology. 19 September 2024. DOI: 10.1016/j.omton.2024.200863.
Geoerger B., Bautista F., André N., Berlanga P., Gatz S.A., Marshall L.V., Rubino J., Archambaud B., Marchais A., Rubio-San-Simón A., Ducassou S., Zwaan C.M., Casanova M., Nysom K., Pellegrino S., Hoog-Labouret N., Buzyn A., Blanc P., Paoletti X., Vassal G.. Precision cancer medicine platform trials: Concepts and design of AcSé-ESMART. European Journal of Cancer. September 2024. DOI: 10.1016/j.ejca.2024.114201.
Impacto: 7.6. Cuartil: Q1
Juan-Ribelles A., Bautista F., Cañete A., Rubio-San-Simón A., Alonso-Saladrigues A., Hladun R., Rives S., Dapena J.L., Fernández J.M., Lassaletta Á., Cruz O., Ramírez-Villar G., Fuster J.L., de Heredia C.D., García-Ariza M., Quiroga E., del Mar Andrés M., Verdú-Amorós J., Molinés A., Herrero B., López M., Márquez C., Toboso M., Lendínez F., Sirvent J.G., Tallón M., Rodríguez G., Acha T., Moreno L., Fernández-Teijeiro A.. ECLIM-SEHOP: how to develop a platform to conduct academic trials for childhood cancer. Clinical and Translational Oncology. September 2024. DOI: 10.1007/s12094-024-03445-0.
Impacto: 2.8. Cuartil: Q2
Parra-Nieto J., Arroyo-Nogales A., Marcos-Fernández D., Jimenez-Falcao S., Arribas C., Megias D., Gonzalez-Murillo Á., Ramirez M., Baeza A.. Dual-pore protocells with multitasking capacities for simultaneous delivery of therapeutic enzymes and drugs in macrophage depletion therapy. Biomaterials Science. 30 August 2024. DOI: 10.1039/d4bm00780h.
Impacto: 5.8. Cuartil: Q1
Marco Sánchez J.M., Bardón Cancho E.J., Benéitez D., Payán-Pernía S., Collado Gimbert A., Ruiz-Llobet A., Salinas J.A., Sebastián E., Argilés B., Bermúdez M., Vázquez M.Á., Ortega M.J., López Rubio M., Gondra A., Uriz J.J., Morado M., Coll M.T., López Duarte M., Baro M., Cervera Á., Recasens V., García Blanes C., del Carcavilla M.P., Tallon M., González Espín A., Olteanu Olteanu F.C., González P., del Mañú Pereira M.M., Cela E.. Haemoglobinopathies and other rare anemias in Spain: ten years of a nationwide registry (REHem-AR). Annals of Hematology. August 2024. DOI: 10.1007/s00277-024-05788-8.
Impacto: 3.0. Cuartil: Q2
de Pablo J.G., Zubicaray J., Iriondo J., Pérez Maroto F., Azorín D., de la Cruz Benito A., Sanz A., Madero L., González-Vicent M., Sevilla J., Sebastián E.. Diagnostic yield of bone marrow aspiration in paediatric primary immune thrombocytopenia: impact of evolution and adherence to medical guidelines over the last 25 years. European Journal of Pediatrics. August 2024. DOI: 10.1007/s00431-024-05583-7.
Impacto: 3.0. Cuartil: Q1
Bautista F., Verdú-Amorós J., Geoerger B., Rubio-San-Simón A., Paoletti X., Zwaan C.M., Casanova M., Marshall L.V., Carceller F., Doz F., Lecinse C., Vassal G., Pearson A.D.J., Kearns P., Moreno L.. Evolution of the Innovative Therapies for Children with Cancer Consortium Trial Portfolio for Drug Development for Children with Cancer. Journal of Clinical Oncology. 20 July 2024. DOI: 10.1200/JCO.23.01237.
Impacto: 42.1. Cuartil: Q1
(1er decil)
Wu J.H., Pennesi E., Bautista F., Garrett M., Fukuhara K., Brivio E., Ammerlaan A.C.J., Locatelli F., van der Sluis I.M., Rossig C., Chen-Santel C., Bielorai B., Petit A., Starý J., Díaz-de-Heredia C., Rives S., O’Marcaigh A., Rizzari C., Engstler G., Nysom K., Rubio-San-Simón A., Bruno B., Bertrand Y., Brethon B., Rialland F., Plat G., Dirksen U., Sramkova L., Zwaan C.M., Huitema A.D.R.. Population Pharmacokinetics of Inotuzumab Ozogamicin in Pediatric Relapsed/Refractory B-Cell Precursor Acute Lymphoblastic Leukemia: Results of Study ITCC-059. Clinical Pharmacokinetics. July 2024. DOI: 10.1007/s40262-024-01386-z.
Impacto: 4.6. Cuartil: Q1
Yoshimi A., Noellke P., Starý J., Kállay K., Smith O., Locatelli F., Buechner J., Bodova I., Sevilla J., Schmugge M., Bierings M., Masmas T., Dworzak M., Labarque V., Pawelec K., Jahnukainen K., Polychronopoulou S., Kjollerstrom P., Kavcic M., Erlacher M., Niemeyer C.M., Strahm B.. Comparison of outcomes of immunosuppressive therapy with rabbit versus horse antithymocyte globulin and cyclosporine a in children with acquired severe aplastic anemia. American Journal of Hematology. July 2024. DOI: 10.1002/ajh.27334.
Impacto: 10.1. Cuartil: Q1
(1er decil)
Fernández-Miranda I., Pedrosa L., González-Rincón J., Espinet B., de la Cruz Vicente F., Climent F., Gómez S., Royuela A., Camacho F.I., Martín-Acosta P., Yanguas-Casás N., Domínguez M., Méndez M., Colomo L., Salar A., Horcajo B., Navarro M., García-Cosío M., Piris-Villaespesa M., Llanos M., García J.F., Sequero S., Mercadal S., García-Hernández S., Navarro B., Mollejo M., Provencio M., Sánchez-Beato M.. Generation and External Validation of a Histologic Transformation Risk Model for Patients with Follicular Lymphoma. Modern Pathology. July 2024. DOI: 10.1016/j.modpat.2024.100516.
Impacto: 7.1. Cuartil: Q1
(1er decil)
Giménez Y., Palacios M., Sánchez-Domínguez R., Zorbas C., Peral J., Puzik A., Ugalde L., Alberquilla O., Villanueva M., Río P., Gálvez E., Da Costa L., Strullu M., Catala A., Ruiz-Llobet A., Segovia J.C., Sevilla J., Strahm B., Niemeyer C.M., Beléndez C., Leblanc T., Lafontaine D.L.J., Bueren J., Navarro S.. Lentivirus-mediated gene therapy corrects ribosomal biogenesis and shows promise for Diamond Blackfan anemia. JCI Insight. 22 May 2024. DOI: 10.1172/jci.insight.171650.
Impacto: 6.3. Cuartil: Q1
Mingot-Castellano M.E., García-Candel F., Martínez-Nieto J., García-Arroba J., de la Rubia-Comos J., Gómez-Seguí I., Paciello-Coronel M.L., Valcárcel-Ferreiras D., Jiménez M., Cid J., Lozano M., García-Gala J.M., Angós-Vazquez S., Vara-Pampliega M., Guerra-Domínguez L., Ávila-Idrobo L.F., Oliva-Hernandez A., Zalba-Marcos S., Tallón-Ruiz I., Ortega-Sánchez S., Goterris-Viciedo R., Moreno-Jiménez G., Domínguez-Acosta L., Araiz-Ramírez M., Hernández-Mateos L., Flores-Ballesteros E., del Río-Garma J., Pascual-Izquierdo C., Abio Calvete M., Albert A., Alberto López García A., Alegre A., Alkorta Eizagirre A., Alonso Escobar M.N., Alonso Madrigal C., Amunarriz C., Antelo Caamaño M.L., Arbona Castaño C., Ballester Ruiz M.C., Ballina Martín B., Berberana Fernández de Murias M., Berrueco Moreno R., Bueno J.L., Calderón López M.T., Chica Gullón E., Cid Vidal J., Contreras Barbeta E., Cuéllar Pérez-Ávila C., Del Orbe Barreto R.A., Díaz Valdés J.R., Diaz-Ricart M., Diez Gallarreta Z., Dueñas Hernando V., Eguia B., Escoda L., Fernández Docampo M., Fernandez Fuertes F., Fernández Muñoz H., Fernández Sánchez de Mora M.C., Fernandez Zarzoso M., Fidalgo T., Flores Ballester E., Fonte Feal C., Galvez F.J., Garcia Arroba Peinado J., Garcia Erce J.A., Gimeno J.J., Gómez D., Gomez Vazquez M.J., Gonzalez C., González Fernández F.A., Gonzalez Porras J.R., Gonzalez Rodriguez V.P., Guillén García H., Hernandez A., Hernández Castellet J.C., Hernandez Mohedo F., Hernandez Vazquez L., Hidalgo Soto M., Hong Tam A.H., Kerguelen Fuentes A.L., Leal Bento M., Lopes R., López O., López Chuliá F., Maria Jose Busto M.J., Martín Hernández M.P., Martinez Estefano E., Martinez Redondo C., Martinez Revuelta E., Medina Marrero L.. ADAMTS13 recovery in acute thrombotic thrombocytopenic purpura after caplacizumab therapy. Blood. 2 May 2024. DOI: 10.1182/blood.2023022725.
Impacto: 21.0. Cuartil: Q1
(1er decil)
Sánchez-Beato M., Méndez M., Guirado M., Pedrosa L., Sequero S., Yanguas-Casás N., de la Cruz-Merino L., Gálvez L., Llanos M., García J.F., Provencio M.. A genetic profiling guideline to support diagnosis and clinical management of lymphomas. Clinical and Translational Oncology. May 2024. DOI: 10.1007/s12094-023-03307-1.
Impacto: 2.8. Cuartil: Q2
Locatelli F., Strålin K.B., Schmid I., Sevilla J., Smith O.P., van den Heuvel-Eibrink M.M., Zecca M., Zwaan C.M., Gaudy A., Patturajan M., Poon J., Simcock M., Niemeyer C.M.. Efficacy and safety of azacitidine in pediatric patients with newly diagnosed advanced myelodysplastic syndromes before hematopoietic stem cell transplantation in the AZA-JMML-001 trial. Pediatric Blood and Cancer. May 2024. DOI: 10.1002/pbc.30931.
Impacto: 2.4. Cuartil: Q1
Iriondo J., Gómez A., Zubicaray J., Garcia-Martinez J., Abad L., Matesanz C., Giménez R., Galán A., Sanz A., Sebastián E., González de Pablo J., de la Cruz A., Ramírez M., Sevilla J.. Optical Genome Mapping as a New Tool to Overcome Conventional Cytogenetics Limitations in Patients with Bone Marrow Failure. Genes. May 2024. DOI: 10.3390/genes15050559.
Impacto: 2.8. Cuartil: Q2
Fiuza-Luces C., Valenzuela P.L., Gálvez B.G., Ramírez M., López-Soto A., Simpson R.J., Lucia A.. The effect of physical exercise on anticancer immunity. Nature Reviews Immunology. April 2024. DOI: 10.1038/s41577-023-00943-0.
Impacto: 67.7. Cuartil: Q1
(1er decil)
Fiuza-Luces C., Valenzuela P.L., Gálvez B.G., Ramírez M., López-Soto A., Simpson R.J., Lucia A.. Correction to: The effect of physical exercise on anticancer immunity (Nature Reviews Immunology, (2023), 10.1038/s41577-023-00943-0). Nature Reviews Immunology. March 2024. DOI: 10.1038/s41577-024-00999-6.
Impacto: 67.7. Cuartil: Q1
(1er decil)
García-Morin M., Bardón-Cancho E.J., Beléndez C., Dulín E., Blanco-Soto P., Puertas-López C., Prieto-Medina M., Cervera-Bravo Á., Llorente-Otones L., Pérez-Alonso V., San-Román S., Vecilla-Rivelles C., López-Rubio M., Sebastián E., Bellón J.M., Cela E.. Madrid Newborn Sickle Cell Disease Cohort: clinical outcomes, stroke prevention and survival. Annals of Hematology. February 2024. DOI: 10.1007/s00277-023-05539-1.
Impacto: 3.0. Cuartil: Q2
Pujol Manresa A., Buendía López S., Andión M., Herrero B., Lassaletta Á., Ramirez M., Ruano D., Hernández-Marqués C., Varo A., de Rojas T., Cortés Hernández M., Verdú-Amorós J., Martín Prado S., Artigas A., Redondo E., Ruiz Pato J., Herreros López P., Sevilla J., Madero L., Moreno L., Bautista Sirvent F., Rubio-San-Simón A.. Safety and outcome of children, adolescents and young adults participating in phase I/II clinical oncology trials: a 9-year center experience. Frontiers in Pediatrics. 2024. DOI: 10.3389/fped.2024.1423484.
Impacto: 2.1. Cuartil: Q2
López de Hontanar Torres G., Zubicaray J., Sebastián E., Hernández-Martín A., Iriondo J., Sevilla J.. Baricitinib in pediatric chronic immune thrombocytopenia and associated autoimmune conditions: a case report. Frontiers in Pediatrics. 2024. DOI: 10.3389/fped.2024.1516039.
Impacto: 2.1. Cuartil: Q2
Zubicaray J., Ivanova M., Iriondo J., García Martínez J., Muñoz-Viana R., Abad L., García-García L., González de Pablo J., Gálvez E., Sebastián E., Ramírez M., Madero L., Díaz M.Á., González-Murillo Á., Sevilla J.. Role of the mesenchymal stromal cells in bone marrow failure of Fanconi Anemia patients. Frontiers in Cell and Developmental Biology. 2024. DOI: 10.3389/fcell.2024.1286815.
Impacto: 4.6. Cuartil: Q1
Corredor B., Solís I., Zubicaray J., Sevilla J., Argente J.. Small pituitary volume and central nervous system anomalies in Fanconi Anemia. Frontiers in Endocrinology. 2024. DOI: 10.3389/fendo.2024.1385650.
Impacto: 3.9. Cuartil: Q2
García-García L., G. Sánchez E., Ivanova M., Pastora K., Alcántara-Sánchez C., García-Martínez J., Martín-Antonio B., Ramírez M., González-Murillo Á.. Choosing T-cell sources determines CAR-T cell activity in neuroblastoma. Frontiers in Immunology. 2024. DOI: 10.3389/fimmu.2024.1375833.
Impacto: 5.7. Cuartil: Q1
Molina Y.L., Blasco-Santana L., Sanz A., Blázquez Gómez C.J., Zubicaray J., Iriondo J., González de Pablo J., Sevilla J., Sebastián E.. Myelofibrosis associated with immune cytopenia in an infant: a diagnostic and therapeutic challenge. Pediatric Hematology and Oncology. 2024. DOI: 10.1080/08880018.2024.2350424.
Impacto: 1.2. Cuartil: Q3
Miera-Maluenda M., Pérez-Torres M., Mañas A., Rubio-San-Simón A., Butjosa-Espín M., Ruiz-Duran P., Seoane J.A., Moreno L., Segura M.F.. Advances in the approaches used to repurpose drugs for neuroblastoma. Expert Opinion on Drug Discovery. 2024. DOI: 10.1080/17460441.2024.2402413.
Impacto: 6.0. Cuartil: Q1
Long-Boyle J.R., Kohn D.B., Shah A.J., Spencer S.M., Sevilla J., Booth C., López Lorenzo J.L., Nicoletti E., Shah A., Reatz M., Matos J., Schwartz J.D.. Busulfan and subsequent malignancy: An evidence-based risk assessment. Pediatric Blood and Cancer. January 2024. DOI: 10.1002/pbc.30738.
Impacto: 2.4. Cuartil: Q1
Garcia-Rodriguez P., Hidalgo L., Rodriguez-Milla M.A., Somovilla-Crespo B., Garcia-Castro J.. LIN28 upregulation in primary human T cells impaired CAR T antitumoral activity. Frontiers in Immunology. 2024. DOI: 10.3389/fimmu.2024.1462796.
Impacto: 5.7. Cuartil: Q1
Jiménez-Reinoso A., Molero-Abraham M., Cirauqui C., Blanco B., Garrido-Martin E.M., Nehme-Álvarez D., Domínguez-Alonso C., Ramírez-Fernández Á., Díez-Alonso L., Nuñez-Buiza Á., González-Murillo Á., Tobes R., Pareja E., Ramírez-Orellana M., Rodriguez-Peralto J.L., Ferrer I., Zugazagoitia J., Paz-Ares L., Álvarez-Vallina L.. CD4<sup>+</sup> tumor-infiltrating lymphocytes secreting T cell-engagers induce regression of autologous patient-derived non-small cell lung cancer xenografts. OncoImmunology. 2024. DOI: 10.1080/2162402X.2024.2392897.
Impacto: 6.5. Cuartil: Q1
Martín-Antonio B., Blanco B., González-Murillo Á., Hidalgo L., Minguillón J., Pérez-Chacón G., Fernández L., Bareke H., París-Muñoz A., Mañas A., Aguirre-Portolés C., Navarro-Zapata A., Mestre-Durán C., Ibáñez-Navarro M., Clares-Villa L., Naharro S., Perez-Martinez A., Aldea M., Gaibar M., Ruiz-Navarro J., Izquierdo M., Zapata J.M., Tarifa E.E., Serrano-López J., Llamas-Sillero P., Murillo Á.G., Sánchez E.G., Martínez J.G., Simón A.R.S., Herrero B., Aguilera G.G., Morera B.H., Orellana M.R., Blanco-Durango B., Jiménez-Reinoso A., Lázaro-Gorines R., Zagorac I., Galisteo A.T., Ramirez-Fernández Á., Díez-Alonso L., Dominguez-Alonso C., Erce-Llamazares A., Hangiu O., Pérez L.R., Rosel M.G., Tudela A.S., Arroyo-Ródena J., Álvarez-Vallina L., Milla M.Á.R., Rodríguez P.G., Crespo B.S., García-Castro J.. Newer generations of multi-target CAR and STAb-T immunotherapeutics: NEXT CART Consortium as a cooperative effort to overcome current limitations. Frontiers in Immunology. 2024. DOI: 10.3389/fimmu.2024.1386856.
Impacto: 5.7. Cuartil: Q1
Isidro-Hernández M., Casado-García A., Oak N., Alemán-Arteaga S., Ruiz-Corzo B., Martínez-Cano J., Mayado A., Sánchez E.G., Blanco O., Gaspar M.L., Orfao A., Alonso-López D., De Las Rivas J., Riesco S., Prieto-Matos P., González-Murillo Á., Criado F.J.G., Cenador M.B.G., Ramírez-Orellana M., de Andrés B., Vicente-Dueñas C., Cobaleda C., Nichols K.E., Sánchez-García I.. Immune stress suppresses innate immune signaling in preleukemic precursor B-cells to provoke leukemia in predisposed mice. Nature Communications. December 2023. DOI: 10.1038/s41467-023-40961-z.
Impacto: 14.7. Cuartil: Q1
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Sebastián E., Andrés-Zallo L., González-Vicent M., Jara M., Molina B., Zubicaray J., Gálvez E., Orfao A., Sevilla J.. Lymphocytic variant hypereosinophilic syndrome successfully treated with hematopoietic stem cell transplantation: A treatment challenge. Pediatric Blood and Cancer. December 2023. DOI: 10.1002/pbc.30698.
Impacto: 2.4. Cuartil: Q1
Rubio-San-Simón A., van Eijkelenburg N.K.A., Hoogendijk R., Hasle H., Niemeyer C.M., Dworzak M.N., Zecca M., Lopez-Yurda M., Janssen J.M., Huitema A.D.R., van den Heuvel-Eibrink M.M., Laille E.J., van Tinteren H., Zwaan C.M.. Azacitidine (Vidaza<sup>®</sup>) in Pediatric Patients with Relapsed Advanced MDS and JMML: Results of a Phase I/II Study by the ITCC Consortium and the EWOG-MDS Group (Study ITCC-015). Pediatric Drugs. November 2023. DOI: 10.1007/s40272-023-00588-5.
Impacto: 3.4. Cuartil: Q1
Lasaga M., Río P., Vilas-Zornoza A., Planell N., Navarro S., Alignani D., Fernández-Varas B., Mouzo D., Zubicaray J., Pujol R.M., Nicoletti E., Schwartz J.D., Sevilla J., Ainciburi M., Ullate- Agote A., Surrallés J., Perona R., Sastre L., Prosper F., Gomez-Cabrero D., Bueren J.A.. Gene therapy restores the transcriptional program of hematopoietic stem cells in Fanconi anemia. Haematologica. October 2023. DOI: 10.3324/haematol.2022.282418.
Impacto: 8.2. Cuartil: Q1
González-Novo R., de Lope-Planelles A., Cruz Rodríguez M.P., González-Murillo Á., Madrazo E., Acitores D., García de Lacoba M., Ramírez M., Redondo-Muñoz J.. 3D environment controls H3K4 methylation and the mechanical response of the nucleus in acute lymphoblastic leukemia cells. European Journal of Cell Biology. September 2023. DOI: 10.1016/j.ejcb.2023.151343.
Impacto: 4.5. Cuartil: Q2
Velasco P., Bautista F., Rubio A., Aguilar Y., Rives S., Dapena J.L., Pérez A., Ramirez M., Saiz-Ladera C., Izquierdo E., Escudero A., Camós M., Vega-García N., Ortega M., Hidalgo-Gómez G., Palacio C., Menéndez P., Bueno C., Montero J., Romecín P.A., Zazo S., Alvarez F., Parras J., Ortega-Sabater C., Chulián S., Rosa M., Cirillo D., García E., García J., Manzano-Muñoz A., Minguela A., Fuster J.L.. The relapsed acute lymphoblastic leukemia network (ReALLNet): a multidisciplinary project from the spanish society of pediatric hematology and oncology (SEHOP). Frontiers in Pediatrics. 22 August 2023. DOI: 10.3389/fped.2023.1269560.
Impacto: 2.1. Cuartil: Q2
Hidalgo L., Somovilla-Crespo B., Garcia-Rodriguez P., Morales-Molina A., Rodriguez-Milla M.A., Garcia-Castro J.. Switchable CAR T cell strategy against osteosarcoma. Cancer Immunology, Immunotherapy. August 2023. DOI: 10.1007/s00262-023-03437-z.
Impacto: 4.6. Cuartil: Q1
López-Nevado M., Sevilla J., Almendro-Vázquez P., Gil-Etayo F.J., Garcinuño S., Serrano-Hernández A., Paz-Artal E., González-Granado L.I., Allende L.M.. Inborn Error of STAT2-Dependent IFN-I Immunity in a Patient Presented with Hemophagocytic Lymphohistiocytosis and Multisystem Inflammatory Syndrome in Children. Journal of Clinical Immunology. August 2023. DOI: 10.1007/s10875-023-01488-6.
Impacto: 7.2. Cuartil: Q1
Català-Senent J.F., Andreu Z., Hidalgo M.R., Soler-Sáez I., Roig F.J., Yanguas-Casás N., Neva-Alejo A., López-Cerdán A., de la Iglesia-Vayá M., Stranger B.E., García-García F.. A deep transcriptome meta-analysis reveals sex differences in multiple sclerosis. Neurobiology of Disease. 1 June 2023. DOI: 10.1016/j.nbd.2023.106113.
Impacto: 5.1. Cuartil: Q1
Zubicaray J., Martin-Consuegra S., Nieto M., Albi G., Iriondo J., Sebastian E., Gálvez E., Molina B., González-Vicent M., de Pablo J.G., Castillo A., Ramírez M., Madero L., Díaz M.A., Sevilla J.. Adverse events related to central venous catheters (CVC) and the influence of CVC characteristics on peripheral blood hematopoietic progenitor cell collection in children. Frontiers in Pediatrics. 19 April 2023. DOI: 10.3389/fped.2023.1131905.
Impacto: 2.1. Cuartil: Q2
Martínez-Álvarez S., Galán-Olleros M., Azorín-Cuadrillero D., Palazón-Quevedo Á., González-Murillo Á., Melen-Frajlich G.J., Ramírez-Orellana M., Epeldegui-Torre T., Forriol F.. Intraosseous injection of mesenchymal stem cells for the treatment of osteonecrosis of the immature femoral head and prevention of head deformity: A study in a pig model. Science Progress. April-June 2023. DOI: 10.1177/00368504231179790.
Impacto: 2.6. Cuartil: Q2
García-Salido A., Flores-Pérez P., González-Murillo Á., Sánchez-Marcos E., Leoz-Gordillo I., Cano-Fernández J., Castillo-Robleda A., Nieto-Moro M., Jiménez-García R.. IgG antispike persistence and immunophenotype in children infected by SARS-CoV-2. Acta Paediatrica, International Journal of Paediatrics. April 2023. DOI: 10.1111/apa.16705.
Impacto: 2.4. Cuartil: Q1
Fox T., Bueren J., Candotti F., Fischer A., Aiuti A., Lankester A., Albert M., Bernardo M.E., Cavazzana M., Ehl S., Neven B., Prevot J., Schambach A., Sevilla J., Thrasher A., Wynn R., Booth C.. Access to gene therapy for rare diseases when commercialization is not fit for purpose. Nature Medicine. March 2023. DOI: 10.1038/s41591-023-02208-8.
Impacto: 58.7. Cuartil: Q1
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Morales-Molina A., Rodriguez-Milla M.Á., Gambera S., Cejalvo T., de Andrés B., Gaspar M.L., García-Castro J.. Toll-like Receptor Signaling–deficient Cells Enhance Antitumor Activity of Cell-based Immunotherapy by Increasing Tumor Homing. Cancer Research Communications. March 2023. DOI: 10.1158/2767-9764.CRC-22-0365.
Parra-Nieto J., García del Cid M.A., Galeano C., de Carcer I.A., García-García L., Gonzalez-Murillo Á., Megias D., Ramirez M., Baeza A.. Multifunctional Nanoassemblies for Cytotoxic Drug and Therapeutic Enzymes Delivery in Neuroblastoma Therapy. Advanced Materials Interfaces. 5 January 2023. DOI: 10.1002/admi.202201356.
Impacto: 4.3. Cuartil: Q2
Rincón-Castanedo C., Martín-Ruiz A., Zazo S., Luis Huertas A.L., Valenzuela P.L., Morán M., Fleck S.J., Santos-Lozano A., Ramírez M., Rojo F., Lucia A., González-Murillo Á., Fiuza-Luces C.. Combined exercise intervention in a mouse model of high-risk neuroblastoma: effects on physical, immune, tumor and clinical outcomes. Exercise immunology review. 2023. DOI: .
Impacto: 3.5. Cuartil: Q1
Fernández-Miranda I., Pedrosa L., Llanos M., Franco F.F., Gómez S., Martín-Acosta P., García-Arroyo F.R., Gumá J., Horcajo B., Ballesteros A.K., Gálvez L., Martínez N., Marín M., Sequero S., Navarro M., Yanguas-Casás N., Calvo V., Rueda-Domínguez A., Provencio M., Sánchez-Beato M.. Monitoring of Circulating Tumor DNA Predicts Response to Treatment and Early Progression in Follicular Lymphoma: Results of a Prospective Pilot Study. Clinical Cancer Research. 1 January 2023. DOI: 10.1158/1078-0432.CCR-22-1654.
Impacto: 10.0. Cuartil: Q1
Ruiz-Llobet A., Gassiot S., Sarrate E., Zubicaray J., Rives S., Suleman W., Berrueco R.. Thrombin generation profile using ST-Genesia after PEG-asparaginase in pediatric patients with acute lymphoblastic leukemia. Thrombosis and Haemostasis. 2023. DOI: 10.1055/a-2316-4547.
Impacto: 5.0. Cuartil: Q1
Cloquell A., Mateo I., Gambera S., Pumarola M., Alemany R., García-Castro J., Perisé-Barrios A.J.. Systemic cellular viroimmunotherapy for canine high-grade gliomas. Journal for ImmunoTherapy of Cancer. 20 December 2022. DOI: 10.1136/jitc-2022-005669.
Sánchez R., Dorado S., Ruíz-Heredia Y., Martín-Muñoz A., Rosa-Rosa J.M., Ribera J., García O., Jimenez-Ubieto A., Carreño-Tarragona G., Linares M., Rufián L., Juárez A., Carrillo J., Espino M.J., Cáceres M., Expósito S., Cuevas B., Vanegas R., Casado L.F., Torrent A., Zamora L., Mercadal S., Coll R., Cervera M., Morgades M., Hernández-Rivas J.Á., Bravo P., Serí C., Anguita E., Barragán E., Sargas C., Ferrer-Marín F., Sánchez-Calero J., Sevilla J., Ruíz E., Villalón L., del Mar Herráez M., Riaza R., Magro E., Steegman J.L., Wang C., de Toledo P., García-Gutiérrez V., Ayala R., Ribera J.M., Barrio S., Martínez-López J.. Detection of kinase domain mutations in BCR::ABL1 leukemia by ultra-deep sequencing of genomic DNA. Scientific Reports. December 2022. DOI: 10.1038/s41598-022-17271-3.
Impacto: 4.6. Cuartil: Q2
Mata Fernández C., Gutierrez Carrasco N., Juan Ribelles A., Hindi Muñiz N., Estival González A., Rubio San Simón A., Portellano L.C., Medina S.R., Morales C.V.. Results of a survey on the treatment of adolescents and young adult (AYA) sarcoma patients in Spain at present time. Clinical and Translational Oncology. December 2022. DOI: 10.1007/s12094-022-02912-w.
Impacto: 3.4. Cuartil: Q3
Sebastián E., Andrés Esteban E.M., González-Vicent M., González de Pablo J., Zubicaray J., Gálvez E., Guillén M., Ruiz Pato J., Molina B., Albi G., Ramírez M., Castillo A., Pérez Maroto F., Madero L., Díaz M.Á., Sevilla J.. Extracorporeal photopheresis in paediatric patients: A retrospective comparison between different ‘off-line’ protocols. Vox Sanguinis. October 2022. DOI: 10.1111/vox.13346.
Impacto: 2.7. Cuartil: Q3
Iriondo J., Zubicaray J., Sebastián E., González de Pablo J., González-Vicent M., Molina B., López-Torija I., Castillo A., Ramírez M., Madero L., Díaz M.Á., Sevilla J.. Mobilization with high-dose granulocyte colony-stimulating factor alone at 12 μg/kg twice a day in high-risk pediatric patients: A retrospective analysis of the experience in a single center. Journal of Clinical Apheresis. October 2022. DOI: 10.1002/jca.21994.
Impacto: 1.5. Cuartil: Q4
González de Pablo J., Jiménez Cobo C., Azorín Cuadrillero D., González-Vicent M., Sevilla J.. Treatment for acquired aplasia and refractory cytopenia. Review of a historical cohort. Anales de Pediatria. October 2022. DOI: 10.1016/j.anpedi.2022.04.016.
Impacto: 2.1. Cuartil: Q3
Grasa Lozano C.D., Baro-Fernández M., Rubio-San-Simón A., Blázquez-Gamero D., López-Roa P., Liébana C., Guerra-García P., Moraleda C., Epalza C.. Tuberculosis screening after detection of a case in a paediatric haemato-oncology unit in a low prevalence country. Enfermedades Infecciosas y Microbiologia Clinica. October 2022. DOI: 10.1016/j.eimc.2020.12.017.
Impacto: 2.5. Cuartil: Q4
Mesa-Núñez C., Damián C., Fernández-García M., Díez B., Rao G., Schwartz J.D., Law K.M., Sevilla J., Río P., Yáñez R., Bueren J.A., Almarza E.. Preclinical safety and efficacy of lentiviral-mediated gene therapy for leukocyte adhesion deficiency type I. Molecular Therapy Methods and Clinical Development. 8 September 2022. DOI: 10.1016/j.omtm.2022.07.015.
Solsona M., Berrueco R., Sebastián E., Cervera Á., Sastre A., Astigarraga I., Argilés B., Dasí M.Á., Dapena J.L., Monteagudo E.. Tapering of the thrombopoietin receptor agonist in paediatric patients with chronic immune thrombocytopenia: Is it possible?. British Journal of Clinical Pharmacology. September 2022. DOI: 10.1111/bcp.15378.
Impacto: 3.4. Cuartil: Q2
Molina B., González-Vicent M., Lopez I., Pereto A., Ruiz J., Ramirez M., Díaz M.A.. Long-term transplant outcomes after allogeneic hematopoietic transplant in pediatric patients with hematological malignancies are influenced by severe chronic graft vs. host disease and immune reconstitution. Frontiers in Pediatrics. 12 August 2022. DOI: 10.3389/fped.2022.947531.
Impacto: 2.6. Cuartil: Q2
Cortes M., Carceller F., Rubio-San-Simón A., Vaidya S.J., Bautista F., Moreno L.. Access to early-phase clinical trials for children with relapsed and refractory neuroblastoma: A multicentre international study. Pediatric Blood and Cancer. August 2022. DOI: 10.1002/pbc.29551.
Impacto: 3.2. Cuartil: Q2
Casado J.A., Valeri A., Sanchez-Dominguez R., Vela P., Lopez A., Navarro S., Alberquilla O., Hanenberg H., Pujol R., Segovia J.C., Minguillon J., Surralles J., De Heredia C.D., Sevilla J., Rio P., Bueren J.A.. Upregulation of NKG2D ligands impairs hematopoietic stem cell function in Fanconi anemia. Journal of Clinical Investigation. 1 August 2022. DOI: 10.1172/JCI142842.
Impacto: 15.9. Cuartil: Q1
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Martín-Carrasco C., Delgado-Bonet P., Tomeo-Martín B.D., Pastor J., de la Riva C., Palau-Concejo P., Del Castillo N., García-Castro J., Perisé-Barrios A.J.. Safety and Efficacy of an Oncolytic Adenovirus as an Immunotherapy for Canine Cancer Patients. Veterinary Sciences. July 2022. DOI: 10.3390/vetsci9070327.
Mingot Castellano M.E., Pascual Izquierdo C., González A., Viejo Llorente A., Valcarcel Ferreiras D., Sebastián E., García Candel F., Sarmiento Palao H., Gómez Seguí I., de la Rubia J., Cid J., Martínez Nieto J., Hernández Mateo L., Goterris Viciedo R., Fidalgo T., Salinas R., del Rio-Garma J.. Recommendations for the diagnosis and treatment of patients with thrombotic thrombocytopenic purpura. Medicina Clinica. 24 June 2022. DOI: 10.1016/j.medcli.2021.03.040.
Impacto: 3.9. Cuartil: Q2
Gonzalez-Vicent M., Molina B., Lopez I., Zubicaray J., Ruiz J., Vicario J.L., Sebastián E., Iriondo J., Castillo A., Abad L., Ramirez M., Sevilla J., Diaz M.A.. T-Cell Depleted Haploidentical Transplantation in Children With Hematological Malignancies: A Comparison Between CD3+/CD19+ and TCRαβ+/CD19+ Depletion Platforms. Frontiers in Oncology. 20 June 2022. DOI: 10.3389/fonc.2022.884397.
Impacto: 4.7. Cuartil: Q2
Fernández-Sevilla L.M., Valencia J., Ortiz-Sánchez P., Fraile-Ramos A., Zuluaga P., Jiménez E., Sacedón R., Martínez-Sánchez M.V., Jazbec J., Debeljak M., Fedders B., Stanulla M., Schewe D., Cario G., Minguela A., Ramírez M., Varas A., Vicente Á.. High BMP4 expression in low/intermediate risk BCP-ALL identifies children with poor outcomes. Blood. 2 June 2022. DOI: 10.1182/blood.2021013506.
Impacto: 20.3. Cuartil: Q1
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Ruiz-Llobet A., Gassiot S., Sarrate E., Zubicaray J., Dapena J.L., Rives S., Sevilla J., Menárguez López Á., Panesso Romero M., Montoya C., Vagace J.M., Molina Hurtado J.R., García-Morín M., García Abós M., Mendoza Sánchez M.C., Lendínez F., Palomo Moraleda P., Tallón M., González B., Urrutia E., Serna J.V., Peláez Pleguezuelos I., Martínez Merino M., Ramos Elbal E., Orellana E., Benítez Muñoz H., Berrueco R.. Venous thromboembolism in pediatric patients with acute lymphoblastic leukemia under chemotherapy treatment. Risk factors and usefulness of thromboprophylaxis. Results of LAL-SEHOP-PETHEMA-2013. Journal of Thrombosis and Haemostasis. June 2022. DOI: 10.1111/jth.15699.
Impacto: 10.4. Cuartil: Q1
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Nieto J.M., Rochas-López S., González-Fernández F.A., Villegas-Martínez A., Bolaños-Calderón E., Salido-Fiérrez E., Cela E., Huerta-Aragoneses J., Ordoñez-García M., Muruzábal-Sitges M.J., Abio-Calvete M., Sevilla Navarro J., de la Iglesia S., Morado M., San Román-Pacheco S., Martín-Mateos M.L., Recasens-Flores M.V., Benavente-Cuesta C., Ropero-Gradilla P., Members of the erithropatology working group . Next generation sequencing for diagnosis of hereditary anemia: Experience in a Spanish reference center. Clinica Chimica Acta. 1 June 2022. DOI: 10.1016/j.cca.2022.03.024.
Impacto: 5.0. Cuartil: Q1
Rabé M., Fonteneau L., Oliver L., Morales-Molina A., Jubelin C., Garcia-Castro J., Heymann D., Gratas C., Vallette F.M.. Cellular Heterogeneity and Cooperativity in Glioma Persister Cells Under Temozolomide Treatment. Frontiers in Cell and Developmental Biology. 25 May 2022. DOI: 10.3389/fcell.2022.835273.
Impacto: 5.5. Cuartil: Q1
Brown G.J., Cañete P.F., Wang H., Medhavy A., Bones J., Roco J.A., He Y., Qin Y., Cappello J., Ellyard J.I., Bassett K., Shen Q., Burgio G., Zhang Y., Turnbull C., Meng X., Wu P., Cho E., Miosge L.A., Andrews T.D., Field M.A., Tvorogov D., Lopez A.F., Babon J.J., López C.A., Gónzalez-Murillo Á., Garulo D.C., Pascual V., Levy T., Mallack E.J., Calame D.G., Lotze T., Lupski J.R., Ding H., Ullah T.R., Walters G.D., Koina M.E., Cook M.C., Shen N., de Lucas Collantes C., Corry B., Gantier M.P., Athanasopoulos V., Vinuesa C.G.. TLR7 gain-of-function genetic variation causes human lupus. Nature. 12 May 2022. DOI: 10.1038/s41586-022-04642-z.
Impacto: 64.8. Cuartil: Q1
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Gargallo P., Bautista F., Juan-Ribelles A., Izquierdo E., Soriano A., de Rojas T., Escudero A., Lavarino C., Solano P., Hladun R., Rubio-San-Simón A., Martínez-Romera I., Calabria I., Olaciregui N.G., Castañeda-Heredia A., de Álava E., Pérez-Martínez A., Astigarraga I., Patiño-García A., Alonso J., Fernández-Teijeiro A., Cañete A., Moreno L.. Current status of precision medicine in pediatric oncology in Spain: a consensus report by the Spanish Society of Paediatric Haematology and Oncology (SEHOP). Clinical and Translational Oncology. May 2022. DOI: 10.1007/s12094-021-02759-7.
Impacto: 3.4. Cuartil: Q3
Blanco M., Collazo-Lorduy A., Yanguas-Casás N., Calvo V., Provencio M.. Unveiling the Role of the Tumor Microenvironment in the Treatment of Follicular Lymphoma. Cancers. May-1 2022. DOI: 10.3390/cancers14092158.
Impacto: 5.2. Cuartil: Q2
Fernández-Sevilla L.M., Belenguer G., Martí-Prado B., Ortiz-Sánchez P., Ramírez M., Varas A., Fariñas I., Vicente Á.. Acute lymphoblastic leukemia cells are able to infiltrate the brain subventricular zone stem cell niche and impair neurogenesis. Haematologica. April 2022. DOI: 10.3324/haematol.2021.279383.
Impacto: 10.1. Cuartil: Q1
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Casado-García A., Isidro-Hernández M., Oak N., Mayado A., Mann-Ran C., Raboso-Gallego J., Alemán-Arteaga S., Buhles A., Sterker D., Sánchez E.G., Martínez-Cano J., Blanco O., Orfao A., Alonso-López D., De Las Rivas J., Riesco S., Prieto-Matos P., González-Murillo Á., Criado F.J.G., Cenador M.B.G., Radimerski T., Ramírez-Orellana M., Cobaleda C., Yang J.J., Vicente-Dueñas C., Weiss A., Nichols K.E., Sánchez-García I.. Transient Inhibition of the JAK/STAT Pathway Prevents B-ALL Development in Genetically Predisposed Mice. Cancer Research. 15 March 2022. DOI: 10.1158/0008-5472.CAN-21-3386.
Impacto: 11.2. Cuartil: Q1
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Moya-Martínez C., Sebastián E., Allende L.M., Gonzalez-Granado L.I., González-Vicent M., Torrelo A.. Eczematous dermatitis and thrombocytopenia in a 10-month-old boy. JEADV Clinical Practice. March 2022. DOI: 10.1002/jvc2.12.
Schwartz J.D., Barcellini W., Grace R.F., Bianchi P., Zanella A., López Lorenzo J.L., Sevilla J., Shah A.J., Glader B., Nicoletti E., Navarro Ordoñez S., Segovia J.C.. Who should be eligible for gene therapy clinical trials in red blood cell pyruvate kinase deficiency (PKD)?: Toward an expanded definition of severe PKD. American Journal of Hematology. 1 March 2022. DOI: 10.1002/ajh.26458.
Impacto: 12.8. Cuartil: Q1
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Madrazo E., González-Novo R., Ortiz-Placín C., García de Lacoba M., González-Murillo Á., Ramírez M., Redondo-Muñoz J.. Fast H3K9 methylation promoted by CXCL12 contributes to nuclear changes and invasiveness of T-acute lymphoblastic leukemia cells. Oncogene. 25 February 2022. DOI: 10.1038/s41388-021-02168-8.
Impacto: 8.0. Cuartil: Q1
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Sevilla J., Iriondo J., Sebastian E., Gonzalez-Vicent M., Schwartz J.D., Zubicaray J.. Letter to the Editor: Hematopoietic Stem and Progenitor Cell Mobilization and Collection for Patients Diagnosed with Osteopetrosis and Hurler Syndrome. Human Gene Therapy. February 2022. DOI: 10.1089/hum.2022.29197.jse.
Impacto: 4.2. Cuartil: Q1
Furundarena J.R., Uranga A., González C., Martínez B., Iriondo J., Ondarra L., Arambarri A., San Vicente R., Sarasqueta C., Lombardi C., Altuna A., Rois N.. Initial study of anaemia profile for primary care centres with automated laboratory algorithms reduces the demand for ferritin, iron, transferrin, vitamin B 12 and folate tests. Journal of Clinical Pathology. 1 February 2022. DOI: 10.1136/jclinpath-2020-207130.
Impacto: 3.4. Cuartil: Q2
Rubio-San-Simón A., Hladun Alvaro R., Juan Ribelles A., Castañeda Heredia A., Guerra-García P., Verdú-Amorós J., Andrés M., Cañete A., Rives S., Pérez-Martínez A., Mora J., Patiño-García A., Lassaleta A., Llort A., Ramírez M., Mata C., Gallego S., Martín-Broto J., Cruz O., Morales La Madrid A., Solano P., Martínez Romera I., Fernández‑Teijeiro A., Bautista F., Moreno L.. The paediatric cancer clinical research landscape in Spain: a 13-year multicentre experience of the new agents group of the Spanish Society of Paediatric Haematology and Oncology (SEHOP). Clinical and Translational Oncology. December 2021. DOI: 10.1007/s12094-021-02649-y.
Impacto: 3.34. Cuartil: Q3
Pedrosa L., Fernández-Miranda I., Pérez-Callejo D., Quero C., Rodríguez M., Martín-Acosta P., Gómez S., González-Rincón J., Santos A., Tarin C., García J.F., García-Arroyo F.R., Rueda A., Camacho F.I., García-Cosío M., Heredero A., Llanos M., Mollejo M., Piris-Villaespesa M., Gómez-Codina J., Yanguas-Casás N., Sánchez A., Piris M.A., Provencio M., Sánchez-Beato M.. Proposal and validation of a method to classify genetic subtypes of diffuse large B cell lymphoma. Scientific Reports. December 2021. DOI: 10.1038/s41598-020-80376-0.
Impacto: 4.996. Cuartil: Q2
Hermida-Prieto M., García-Castro J., Mariñas-Pardo L.. Systemic treatment of immune-mediated keratoconjunctivitis sicca with allogeneic stem cells improves the schirmer tear test score in a canine spontaneous model of disease. Journal of Clinical Medicine. December-2 2021. DOI: 10.3390/jcm10245981.
Impacto: 4.964. Cuartil: Q2
Perisé-Barrios A.J., Tomeo-Martín B.D., Gómez-Ochoa P., Delgado-Bonet P., Plaza P., Palau-Concejo P., González J., Ortiz-Díez G., Meléndez-Lazo A., Gentil M., García-Castro J., Barbero-Fernández A.. Humoral responses to SARS-CoV-2 by healthy and sick dogs during the COVID-19 pandemic in Spain. Veterinary Research. December 2021. DOI: 10.1186/s13567-021-00897-y.
Impacto: 3.829. Cuartil: Q1
(1er decil)
Carreño-Tarragona G., Varghese L.N., Sebastián E., Gálvez E., Marín-Sánchez A., López-Muñoz N., Nam-Cha S., Martínez-López J., Constantinescu S.N., Sevilla J., Ayala R.. A typical acute lymphoblastic leukemia JAK2 variant, R683G, causes an aggressive form of familial thrombocytosis when germline. Leukemia. November 2021. DOI: 10.1038/s41375-021-01239-9.
Impacto: 12.883. Cuartil: Q1
(1er decil)
Yanguas-Casás N., Torres C., Crespo-Castrillo A., Diaz-Pacheco S., Healy K., Stanton C., Chowen J.A., Garcia-Segura L.M., Arevalo M.A., Cryan J.F., de Ceballos M.L.. High-fat diet alters stress behavior, inflammatory parameters and gut microbiota in Tg APP mice in a sex-specific manner. Neurobiology of Disease. November 2021. DOI: 10.1016/j.nbd.2021.105495.
Impacto: 7.046. Cuartil: Q1
Rubio San Simón A., de Rojas de Pablo T.. Advances in the treatment of childhood cancer. Pediatria Integral. Oct-Nov 2021. DOI: .
Sevilla J., Navarro S., Rio P., Sánchez-Domínguez R., Zubicaray J., Gálvez E., Merino E., Sebastián E., Azqueta C., Casado J.A., Segovia J.C., Alberquilla O., Bogliolo M., Román-Rodríguez F.J., Giménez Y., Larcher L., Salgado R., Pujol R.M., Hladun R., Castillo A., Soulier J., Querol S., Fernández J., Schwartz J., García de Andoín N., López R., Catalá A., Surralles J., Díaz-de-Heredia C., Bueren J.A.. Improved collection of hematopoietic stem cells and progenitors from Fanconi anemia patients for gene therapy purposes. Molecular Therapy Methods and Clinical Development. 10 September 2021. DOI: 10.1016/j.omtm.2021.06.001.
Impacto: 5.849. Cuartil: Q2
Manzano-Muñoz A., Alcon C., Menéndez P., Ramírez M., Seyfried F., Debatin K.M., Meyer L.H., Samitier J., Montero J.. MCL-1 Inhibition Overcomes Anti-apoptotic Adaptation to Targeted Therapies in B-Cell Precursor Acute Lymphoblastic Leukemia. Frontiers in Cell and Developmental Biology. 9 September 2021. DOI: 10.3389/fcell.2021.695225.
Impacto: 6.081. Cuartil: Q1
López-Nevado M., González-Granado L.I., Ruiz-García R., Pleguezuelo D., Cabrera-Marante O., Salmón N., Blanco-Lobo P., Domínguez-Pinilla N., Rodríguez-Pena R., Sebastián E., Cruz-Rojo J., Olbrich P., Ruiz-Contreras J., Paz-Artal E., Neth O., Allende L.M.. Primary Immune Regulatory Disorders With an Autoimmune Lymphoproliferative Syndrome-Like Phenotype: Immunologic Evaluation, Early Diagnosis and Management. Frontiers in Immunology. 10 August 2021. DOI: 10.3389/fimmu.2021.671755.
Impacto: 8.786. Cuartil: Q1